Results 71 to 80 of about 25,608 (226)

Antimicrobial Activity of Solanum torvum Crude Extracts against Important Mycobacterial Strains

International Journal of Mycobacteriology
Background: Tuberculosis (TB) caused by Mycobacterium tuberculosis (M. tb) complex remains a leading cause of morbidity and mortality worldwide. The zoonotic infectious condition represents a never-ending challenge for which drug discovery efforts are ...
Joseph Mwanzia Nguta
doaj   +1 more source

Synthesis and Antibacterial Evaluation of a New Series of <em>N</em>-Alkyl-2-alkynyl/(<em>E</em>)-alkenyl-4-(1<em>H</em>)-quinolones

Molecules, 2012
To gain further insight into the structural requirements of the aliphatic group at position 2 for their antimycobacterial activity, some <em>N</em>-alkyl-4-(1<em>H</em>)-quinolones bearing position 2 alkynyls with various chain ...
Abraham Wube, Juan-David Guzman, Antje Hüfner, Christina Hochfellner, Martina Blunder, Rudolf Bauer, Simon Gibbons, Sanjib Bhakta, Franz Bucar   +8 more
doaj   +1 more source

Design, Synthesis, and Biological Evaluation of Novel Thiazolidinone-Containing Quinoxaline-1,4-di-N-oxides as Antimycobacterial and Antifungal Agents

Frontiers in Chemistry, 2020
Tuberculosis and fungal infections can pose serious threats to human health. In order to find novel antimicrobial agents, 26 novel quinoxaline-1,4-di-N-oxides containing a thiazolidinone moiety were designed and synthesized, and their antimycobacterial ...
Heying Zhang, Heying Zhang, Jie Zhang, Jie Zhang, Wei Qu, Shuyu Xie, Lingli Huang, Lingli Huang, Dongmei Chen, Yanfei Tao, Zhenli Liu, Zhenli Liu, Yuanhu Pan, Yuanhu Pan, Zonghui Yuan, Zonghui Yuan   +15 more
doaj   +1 more source

Antimycobacterial Activity of Salicylanilide Benzenesulfonates [PDF]

Molecules, 2012
A series of eighteen novel esters of salicylanilides with benzenesulfonic acid were designed, synthesized and characterized by IR, 1H-NMR and 13C-NMR. They were evaluated in vitro as potential antimycobacterial agents towards Mycobacterium tuberculosis, Mycobacterium avium and two strains of Mycobacterium kansasii.
Jiřina Stolaříková, Jarmila Vinšová, Martin Krátký, Nabila Guisado Rodriguez   +3 more
openaire   +3 more sources

Diffuse Large B‐Cell Lymphoma With Pulmonary and Gastric Involvement Mimicking Nontuberculous Mycobacterial Lung Disease

Respirology Case Reports, Volume 14, Issue 5, May 2026.
An 81‐year‐old man presented with multiple bilateral pulmonary nodules and detection of Mycobacterium intracellulare, initially suggesting nontuberculous mycobacterial lung disease. However, heterogeneous radiological changes and progressive enlargement of selected nodules led to surgical lung biopsy, which revealed diffuse large B‐cell lymphoma with ...
Kosuke Masuda, Kazuhiro Asada, Yuu Saitoh, Makoto Suzuki, Emi Fukasawa, Yumi Fujita, Kosuke Suzuki, Sho Murai, Daisuke Akahori, Mika Saigusa, Taisuke Akamatsu, Akito Yamamoto, Satoru Morita, Toshihiro Shirai   +13 more
wiley   +1 more source

Structure based de novo design of IspD inhibitors as anti-tubercular agents [PDF]

, 2012
Tuberculosis is one of the leading contagious diseases, caused by Mycobacterium tuberculosis. Despite improvements in anti-tubercular agents, it remains one of the most prevalent infectious diseases worldwide, responsible for a total of 1.6 million ...
Abhay T. Sangamwar, Gaurao V. Dhoke, Rahul P. Gangwal, Rohith Anand Varikoti, Venkata Krishnan Ramaswamy   +4 more
core   +2 more sources

Clinical Images: A thorn injury, a sea‐borne culprit, and a tenosynovitis dilemma

Arthritis &Rheumatology, EarlyView.
Jacopo Ciaffi, Francesco Mori, Paolo Sassu, Marco Gambarotti, Alberto Righi, Eleonora Zamparini, Marco Innocenti, Marina Tadolini, Francesco Ursini   +8 more
wiley   +1 more source

Cutaneous non‐tuberculous mycobacterial infections: A retrospective study of 94 cases from Germany

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 5, Page 608-617, May 2026.
Summary Background Cutaneous non‐tuberculous mycobacterial infections (NTM) remain a diagnostic and therapeutic challenge. The aim of this study was to characterize cutaneous NTM infections in Germany over a 24‐year‐period. Patients and Methods 73 patients with cutaneous NTM infections diagnosed at 17 different German University Hospitals from 2000 ...
Luisa Bopp, Nicolai Deresz, Henning Klapproth, Isabelle Suárez, Jonathan Jantsch, Mario Fabri, Esther von Stebut   +6 more
wiley   +1 more source

Antimycobacterial Activities of Endolysins Derived From a Mycobacteriophage, BTCU-1

Molecules, 2015
The high incidence of Mycobacterium infection, notably multidrug-resistant M. tuberculosis infection, has become a significant public health concern worldwide.
Meng-Jiun Lai, Chih-Chin Liu, Shinn-Jong Jiang, Po-Chi Soo, Meng-Hsuan Tu, Jen-Jyh Lee, Ying-Huei Chen, Kai-Chih Chang   +7 more
doaj   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, Volume 15, Issue 14, 10 April 2026.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source