Results 51 to 60 of about 11,110 (180)

What Is the Significance of an Accelerated BCG Reaction in Children Living in Low Tuberculosis Incidence Countries?

Journal of Paediatrics and Child Health, Volume 62, Issue 7, Page 1186-1191, July 2026.
ABSTRACT Aim In high tuberculosis (TB) incidence countries, accelerated Bacille Calmette–Guérin (BCG) reactions are considered markers of prior Mycobacterium tuberculosis exposure and may prompt investigation. Their significance in low‐incidence countries is unclear.
Widad Al Salmi, Niall Johnston, Emma Birrell, Adam W. Bartlett, Pamela Palasanthiran, Brendan J. McMullan, Phoebe C. M. Williams   +6 more
wiley   +1 more source

Antimicrobial Activity of Solanum torvum Crude Extracts against Important Mycobacterial Strains

International Journal of Mycobacteriology
Background: Tuberculosis (TB) caused by Mycobacterium tuberculosis (M. tb) complex remains a leading cause of morbidity and mortality worldwide. The zoonotic infectious condition represents a never-ending challenge for which drug discovery efforts are ...
Joseph Mwanzia Nguta
doaj   +1 more source

Antimycobacterial and cytotoxicity activity of microcystins [PDF]

Journal of Venomous Animals and Toxins including Tropical Diseases, 2015
The present work aimed to evaluate the antimycobacterial activity and cytotoxicity of Microcystis aeruginosa toxins, the MC-LR variant and purified extract of [D-Leu(1)] microcystin-LR.The antimicrobial activity of M. aeruginosa extract and microcystin was evaluated by resazurin microtiter assay against Mycobacterium tuberculosis, M.
Ramos, Daniela Fernandes, Matthiensen, Alexandre, Colvara, Wilson, Votto, Ana Paula Souza de, Trindade, Gilma Santos, Silva, Pedro Eduardo Almeida da, Yunes, João Sarkis   +6 more
openaire   +5 more sources

Should TNF inhibitors be avoided in psoriasis patients with latent tuberculosis?

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Fabià Torres‐Betato, Lluís Puig
wiley   +1 more source

Small molecule and fragment-based phenotypic screening for novel building blocks with antimycobacterial activity [PDF]

Exploration of Drug Science
Aim: To design, synthesize, and test small molecules and fragment-based compounds with putative selective anti-mycobacterial activity. Methods: Standard chemosynthetic processes were used to synthesize 42 compounds.
Monika I. Konaklieva, Kriti Arora, Helena I. M. Boshoff, Balbina J. Plotkin   +3 more
doaj   +1 more source

Synthesis and Antibacterial Evaluation of a New Series of <em>N</em>-Alkyl-2-alkynyl/(<em>E</em>)-alkenyl-4-(1<em>H</em>)-quinolones

Molecules, 2012
To gain further insight into the structural requirements of the aliphatic group at position 2 for their antimycobacterial activity, some <em>N</em>-alkyl-4-(1<em>H</em>)-quinolones bearing position 2 alkynyls with various chain ...
Abraham Wube, Juan-David Guzman, Antje Hüfner, Christina Hochfellner, Martina Blunder, Rudolf Bauer, Simon Gibbons, Sanjib Bhakta, Franz Bucar   +8 more
doaj   +1 more source

Design, Synthesis, and Biological Evaluation of Novel Thiazolidinone-Containing Quinoxaline-1,4-di-N-oxides as Antimycobacterial and Antifungal Agents

Frontiers in Chemistry, 2020
Tuberculosis and fungal infections can pose serious threats to human health. In order to find novel antimicrobial agents, 26 novel quinoxaline-1,4-di-N-oxides containing a thiazolidinone moiety were designed and synthesized, and their antimycobacterial ...
Heying Zhang, Heying Zhang, Jie Zhang, Jie Zhang, Wei Qu, Shuyu Xie, Lingli Huang, Lingli Huang, Dongmei Chen, Yanfei Tao, Zhenli Liu, Zhenli Liu, Yuanhu Pan, Yuanhu Pan, Zonghui Yuan, Zonghui Yuan   +15 more
doaj   +1 more source

Dual‐Peptide Nanoplatform: Mesoporous Silica Nanoparticles Functionalized With a Cell‐Penetrating Peptide and Loaded With Rationally Designed Antimicrobial Peptides for Tuberculosis Therapy

Advanced Healthcare Materials, Volume 15, Issue 21, 5 June 2026.
Machine learning–guided engineering of a plectasin‐derived peptide yields DC05, a potent antimycobacterial candidate. Encapsulation into tuftsin‐functionalized mesoporous silica nanoparticles enhances intracellular delivery, stability, and activity against Mycobacterium tuberculosis while maintaining low cytotoxicity and minimal hemolysis. The combined
Christian S. Carnero Canales, Cesar Augusto Roque‐Borda, Ana Carolina Cerqueira Negri, Oswaldo Ramirez Delgado, Letícia Oliveira Catarin Nunes, Flávia Aparecida Resende, Hernane Barud, Norival Alves Santos‐Filho, Saulo Santesso Garrido, Karen Cristina Oliveira, Alexandra Ivo de Medeiros, Rafael Miguel Sábio, Fernando Rogério Pavan   +12 more
wiley   +1 more source

Traditional Respiratory Remedies From Anatolia: Ethnobotanical Insights and Bioactive Properties

Chemistry &Biodiversity, Volume 23, Issue 6, June 2026.
ABSTRACT Respiratory disorders, ranging from acute viral infections such as influenza and bronchitis to chronic inflammatory conditions including chronic obstructive pulmonary disease, asthma, emphysema, and pneumonia, represent a major global health burden, affecting millions annually. Traditional Anatolian folk medicine has long relied on plant‐based
Golshan Zare, Yağmur Diker, Irem Tatlı Çankaya, Emran Habibi, Satyajit D. Sarker, Lutfun Nahar   +5 more
wiley   +1 more source

Idiopathic Granulomatous Mastitis in a Nulliparous Woman With Autism Spectrum Disorder Receiving Long‐Term Psychotropic Treatment and Normal Serum Prolactin Level: A Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Idiopathic granulomatous mastitis (IGM) is a rare inflammatory breast disorder, primarily attributed to immunological dysregulation, hormonal imbalances, or fertility‐related conditions. We report a 26‐year‐old female with autism spectrum disorder (ASD) under long‐term multidrug psychotropic treatment who developed IGM.
Esmat Davoudi‐Monfared, Fatemeh Shahabi, Asieh Sadat Fattahi, Marzieh Rahimi, Mahsa Akbari Oryani, Azadeh Jabbari Nooghabi   +5 more
wiley   +1 more source