Results 51 to 60 of about 25,608 (226)

Identification of a 3-Alkylpyridinium Compound from the Red Sea Sponge Amphimedon chloros with In Vitro Inhibitory Activity against the West Nile Virus NS3 Protease. [PDF]

, 2018
Viruses are underrepresented as targets in pharmacological screening efforts, given the difficulties of devising suitable cell-based and biochemical assays.
Duggan, Brendan M, Emwas, Abdul-Hamid, Gerwick, William H, Kharbatia, Najeh, Kremb, Stephan, O'Rourke, Aubrie, Raji, Misjudeen, Sioud, Salim, Voolstra, Christian R   +8 more
core   +3 more sources

Bibliometric Analysis of Cubebenes and Related Sesquiterpenes: Natural Occurrence, Biosynthesis, Pharmacological Activities, and In‐Silico‐Based Future Therapeutic Potential

eFood, Volume 7, Issue 3, June 2026.
Cubebene‐related sesquiterpenes, found across diverse biological sources, exhibit promising pharmacological activities, including anti‐inflammatory, neuroprotective, and anticancer effects. This review highlights their molecular diversity, ADME profiles, and predicted multitarget interactions, underscoring their therapeutic relevance and potential in ...
Khadija Boualam, Ahmet B. Ortaakarsu, Sohaib Khatib, Mohamed A. Farag, Mansour Sobeh   +4 more
wiley   +1 more source

Synthesis of non-purine analogs of 6-aryl-9-benzylpurines, and their antimycobacterial activities : compounds modified in the imidazole ring [PDF]

, 2010
Purine analogs modified in the five-membered ring have been synthesized and examined for antibacterial activity against Mycobacterium tuberculosis H37Rv in vitro employing the microplate alamar blue assay (MABA). The 9-deaza analogs were only found to be
Charnock, Colin, Franzblau, Scott, Gundersen, Lise-Lotte, Khoje, Abhijit Datta, Kulendrn, Aisvareya, Wan, Baojie   +5 more
core   +2 more sources

Antimycobacterial Activity of Allium Cepa and Allium sativum Hydroethanolic Crude Extracts against Pathogenic and Nonpathogenic Mycobacterial Strains

International Journal of Mycobacteriology
Background: Tuberculosis (TB) caused by Mycobacterium tuberculosis complex remains a leading cause of morbidity and mortality worldwide. The zoonotic infectious condition represents a never-ending challenge toward which drug discovery efforts are needed.
Joseph Mwanzia Nguta
doaj   +1 more source

In vitro Antimycobacterial, Apoptosis-Inducing Potential, and Immunomodulatory Activity of Some Rubiaceae Species

Frontiers in Pharmacology, 2019
Tuberculosis (TB), a disease caused by microorganisms of the Mycobacterium tuberculosis complex, infects almost one-third of the world’s population. The TB epidemic has been further exacerbated by the emergence of multi, extensively, and totally-drug ...
Abimbola O. Aro, Abimbola O. Aro, Jean Paul Dzoyem, Jean Paul Dzoyem, Amelia Goddard, Pascaline Fonteh, Prudence N. Kayoka-Kabongo, Lyndy J. McGaw   +7 more
doaj   +1 more source

HPLC-DAD and UHPLC/QTOF-MS Analysis of Polyphenols in Extracts of the African Species Combretum padoides, C. zeyheri and C. psidioides Related to Their Antimycobacterial Activity

Antibiotics, 2020
Combretum padoides Engl. & Diels, C. psidioides Welv. and C. zeyheri Sond. are used for the treatment of infections and tuberculosis related symptoms in African traditional medicine.
Pia Fyhrquist, Enass Y. A. Salih, Satu Helenius, Into Laakso, Riitta Julkunen-Tiitto   +4 more
doaj   +1 more source

The Potential Effect of Elevated Root Zone Temperature on the Concentration of Chlorogenic, Caffeic, and Ferulic acids and the Biological Activity of Some Pigmented Solanum tuberosum L. Cultivar Extracts

Applied Sciences, 2021
Without a doubt, potatoes play a vital food and nutrition security role in the world as more than a billion people consume this vegetable. Furthermore, the polyphenolic constituents of pigmented potato cultivars and their associated health benefits have ...
Hildegard Witbooi, Callistus Bvenura, Anna-Mari Reid, Namrita Lall, Oluwafemi Omoniyi Oguntibeju, Learnmore Kambizi   +5 more
doaj   +1 more source

Antibiotic Exposure in Early Life and Risk of Type 1 Diabetes: A Meta‐Analysis

Diabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 4653-4670, June 2026.
ABSTRACT Background Early‐life antibiotic use may increase the risk of childhood type 1 diabetes (T1D), potentially through gut microbiota dysbiosis and associated effects on immune development. This meta‐analysis evaluated associations between early‐life antibiotic use and T1D.
Sharan Ram, Marine Corbin, Andrea ’t Mannetje, Jeroen Douwes, Amanda Kvalsvig, Amanda Eng   +5 more
wiley   +1 more source

Isolation and identification of Bacillus strains with antimycobacterial activity [PDF]

, 2011
Tuberculosis is the principal cause of death worldwide due to an infectious disease. The resurgence of tuberculosis, followed by the increase in prevalence of infections caused by nontuberculous mycobacteria (NTM), as well as the multi-drug resistance ...
Abdellah, Houari, Abdellatif, Haggoud, David, Susana, El Guendouzi, Souraya, Mohammed, Hassi, Mohammed, Iraqui, Saad Ibn, Souda   +6 more
core   +1 more source

UHPLC-HRMS/MS Chemical Fingerprinting of the Bioactive Partition from Cultivated Piper aduncum L.

Molecules
Piper aduncum L. is widely distributed in tropical regions and the ethnobotanical uses of this species encompass medicinal applications for the treatment of respiratory, antimicrobial, and gynecological diseases.
Adélia Viviane de Luna, Thayssa da Silva Ferreira Fagundes, Ygor Jessé Ramos, Marlon Heggdorne de Araújo, Michelle Frazão Muzitano, Sanderson Dias Calixto, Thatiana Lopes Biá Ventura Simão, George Azevedo de Queiroz, Elsie Franklin Guimarães, André Mesquita Marques, Davyson de Lima Moreira   +10 more
doaj   +1 more source