Results 41 to 50 of about 11,110 (180)

Cutaneous Mycobacterium haemophilum Infection in an Immunosuppressed Host: A Case Report of Diagnostic Considerations and Microbiologic Confirmation

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Cutaneous Mycobacterium haemophilum infection may be missed due to its requirement for iron supplementation and low‐temperature incubation, making early consideration of NTM infection and use of molecular diagnostics essential, particularly in immunocompromised hosts where IRIS may mimic disease progression.
Angus Lane, Amanda Godbolt, Sarah Morton, Heather Wiseby, Vivek Menon, Chris Coulter, Sushil Pandey, Andrew Burke   +7 more
wiley   +1 more source

MEP Pathway: First-Synthesized IspH-Directed Prodrugs with Potent Antimycobacterial Activity

Microorganisms
We report the first synthesis of IspH-directed prodrugs targeting the terminal enzyme of the 2-C-methyl-D-erythritol 4-phosphate (MEP) pathway, (E)-4-hydroxy-3-methylbut-2-enyl diphosphate reductase (IspH or LytB).
Alizée Allamand, Ludovik Noël-Duchesneau, Cédric Ettelbruck, Edgar De Luna, Didier Lièvremont, Catherine Grosdemange-Billiard   +5 more
doaj   +1 more source

Integrative In Vitro and In Silico Evaluation of the Chemical Profile and Bioactivities of Tetraclinis articulata Essential Oil

ChemistrySelect, Volume 11, Issue 27, 17 July 2026.
Chemistry and bioactivity of Tetraclinis articulata EO: in vitro and in silico investigation. Insights into chemistry and bioactivities of T. articulata EO. ABSTRACT This research focuses on characterizing the chemical composition and evaluate the biological potentials of the Tetraclinis articulata essential oil (TAEO) extracted from aerial parts of ...
Bochra Medjadji, Fatiha Benahmed, Fatima Kerroum, Imededdine Kadi, Khelifa Bouacem, Fairouz El Aichar, Mohamed Abdesselem Dems, Tarek H. Taha, Walid Elfalleh, Stefania Garzoli, Hamdi Bendif   +10 more
wiley   +1 more source

Synthesis of novel triazole hybrids with pyrene, fluorene, and biphenyl groups and evaluation of their antimycobacterial activity

Heterocyclic Communications
The synthesis of 1,2,3-triazoles, which are acting as promising pharmacophores with strong biological activity, is the focus of our work. Three obscure streaks of hybrid molecules with a 1,2,3-triazole nucleus have been synthesized by us.
Goyal Akshi, Bhandari Meena
doaj   +1 more source

Structural insights into multitargeting Mycobacterium tuberculosis Pkn kinases

Microbiology Spectrum
Tuberculosis remains one of the leading major global health challenges, driven by the emergence of multidrug-resistant and extensively drug-resistant bacterial strains.
Angelika Pölläniemi, Ya Miao, Lotta Laitila, Hannaleena Piippo, Milka Hammarén, Mataleena Parikka, Teemu Haikarainen   +6 more
doaj   +1 more source

HPLC-DAD and UHPLC/QTOF-MS Analysis of Polyphenols in Extracts of the African Species Combretum padoides, C. zeyheri and C. psidioides Related to Their Antimycobacterial Activity

Antibiotics, 2020
Combretum padoides Engl. & Diels, C. psidioides Welv. and C. zeyheri Sond. are used for the treatment of infections and tuberculosis related symptoms in African traditional medicine.
Pia Fyhrquist, Enass Y. A. Salih, Satu Helenius, Into Laakso, Riitta Julkunen-Tiitto   +4 more
doaj   +1 more source

Clinical Images: A thorn injury, a sea‐borne culprit, and a tenosynovitis dilemma

Arthritis &Rheumatology, EarlyView.
Jacopo Ciaffi, Francesco Mori, Paolo Sassu, Marco Gambarotti, Alberto Righi, Eleonora Zamparini, Marco Innocenti, Marina Tadolini, Francesco Ursini   +8 more
wiley   +1 more source

Blood Immunopathology of Tuberculosis Patients Disrupts Monocyte‐Dependent T‐Cell Activation and Cytokine Expression

Immunology, Volume 178, Issue 3, Page 494-505, July 2026.
TB serum selectively disrupts monocyte‐dependent PHA T cell activation and cytokines associated with proliferation while preserving SEB T cell and Pam3/PHA monocyte cytokine responses. ABSTRACT Pulmonary tuberculosis in humans is characterised by features of immunopathology, which influence both antimycobacterial therapy and the long‐term prognosis. In
Joseph F. Arthur, Hubert S. Ahor, Monika M. Vivekanandan, Difery Minadzi, Augustine Yeboah, Millicent Lamptey, Victoria A. Ofori, Albert D. Kegya, Rejoice Arthur, Linda A. Amoakoa, Ernest Adankwah, Dorcas O. Owusu, Mohammed K. Abass, Fredrick Gyamfi Apraku, Nana K. Ayisi‐Boateng, Seth Adane, Salisu Zakaria, Ertan Mayatepek, Julia Seyfarth, Richard O. Phillips, Marc Jacobsen   +20 more
wiley   +1 more source

Antitubercular Activity of 7-Methyljuglone-Loaded Poly-(Lactide Co-Glycolide) Nanoparticles

Pharmaceutics
Background/Objectives: Loading of natural products into poly-(lactide-co-glycolic) acid (PLGA) nanoparticles as drug delivery systems for the treatment of diseases, such as tuberculosis (TB), has been widely explored.
Bianca Diedericks, Anna-Mari Kok, Vusani Mandiwana, Bhavna Gowan Gordhan, Bavesh Davandra Kana, Suprakas Sinha Ray, Namrita Lall   +6 more
doaj   +1 more source

In-vitro evaluation of the antibacterial activity of the essential oils of Micromeria barbata, Eucalyptus globulus and Juniperus excelsa against strains of Mycobacterium tuberculosis (including MDR), Mycobacterium kansasii and Mycobacterium gordonae

Journal of Infection and Public Health, 2019
Background: Mycobacterium spp. are responsible for several diseases, particularly in immunocompromised populations. The spreading of the resistance to antimycobacterial drugs is a significant problem to the public health and requires to find out a new ...
Khaled El Omari, Monzer Hamze, Saer Alwan, Marwan Osman, Charafeddine Jama, Nour-Eddine Chihib   +5 more
doaj   +1 more source