Results 11 to 20 of about 14,174 (200)
The Antinociceptive Activity of Geraniol [PDF]
Comment on: Geraniol Induces Antinociceptive Effect in Mice Evaluated in Behavioural and Electrophysiological Models. [Basic Clin Pharmacol Toxicol. 2017]
Chirumbolo, Salvatore, Bjørklund, Geir
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Antinociceptive Properties of Bergenin [PDF]
Bergenin (1) is a C-glucoside of 4-O-methylgallic acid with known antiarthritic activity attributed to modulation of cytokine production. The present study was undertaken to evaluate whether 1 has antinociceptive properties in models of inflammatory pain and to investigate its possible mechanisms of action.
Cristiane Metzker, de Oliveira +7 more
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Neurotensin-induced antinociception in mice: antagonism by thyrotropin-releasing hormone
Neurotensin (NT), administered intracisternally to mice, produced significant dose-dependent antinociception in three analgesic tests: tail immersion, hot-plate and acetic acid writhing. Naloxone (1-5 mg/kg), an opiate antagonist administered i.p. 20 min
Nemeroff, C B +4 more
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Investigation into atropine‐induced antinociception [PDF]
The effect of atropine on the nociceptive system was examined in mice and rats by use of the hot‐plate, writhing and tail‐flick tests.Atropine dose‐dependently produced analgesia, no effect and hyperalgesia. Analgesia was observed in both species with doses ranging from 1 to 100 μg kg−1while hyperalgesia was obtained with 5 mg kg−1.Atropine ...
GHELARDINI, CARLA +4 more
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Background: Diverse studies suggest that non-steroidal anti-inflammatory drugs (NSAIDs) induce antinociception through the inhibition of cyclooxygenases.
Viviana Noriega +6 more
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Additive interaction of intrathecal ginsenosides and neostigmine in the rat formalin test [PDF]
BackgroundThe authors evaluated the effect of intrathecal mixture of ginsenosides with neostigmine on formalin-induced nociception and made further clear the role of the spinal muscarinic (M) receptors on the activity of ginsenosides.MethodsA catheter ...
Cheon-Hee Park +3 more
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The antinociceptive effect of esmolol [PDF]
Esmolol is the first intravenous, short-acting, titratable β-blocker available for use in critical care and surgical settings [1]. Esmolol is thought to be a "jack of all trades" among drugs used in anesthesia because it prevents and treats cardiovascular responses due to perioperative stimuli.
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(1) Background: The diagnostic and therapeutic procedures performed under sedation or general anesthesia in bovines are numerous. The analgesic drugs that can be legally used are few, making perioperative analgesia challenging.
Ekaterina Gámez Maidanskaia +4 more
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Antinociceptive Effect of Hydroxydihydrocarvone
Hydroxydihydrocarvone (HC) is a synthetic intermediate obtained from R-(-)-carvone hydration. Due to the chemical and structural similarity between HC and other monoterpenes with psychopharmacological activity, this study was carried out to investigate the possible central antinociceptive effect of intraperitoneally administered HC, and to evaluate its
Oliveira, Fernando de Sousa +2 more
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.: Oxaliplatin is a chemotherapeutic agent that induces chronic refractory neuropathy. To determine whether opioids effectively relieve this chronic neuropathy, we investigated the efficacies of morphine, oxycodone, and fentanyl, and the mechanisms ...
Tomoe Kanbara +9 more
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