Results 11 to 20 of about 14,174 (200)

The Antinociceptive Activity of Geraniol [PDF]

open access: yesBasic & Clinical Pharmacology & Toxicology, 2016
Comment on: Geraniol Induces Antinociceptive Effect in Mice Evaluated in Behavioural and Electrophysiological Models. [Basic Clin Pharmacol Toxicol. 2017]
Chirumbolo, Salvatore, Bjørklund, Geir
openaire   +3 more sources

Antinociceptive Properties of Bergenin [PDF]

open access: yesJournal of Natural Products, 2011
Bergenin (1) is a C-glucoside of 4-O-methylgallic acid with known antiarthritic activity attributed to modulation of cytokine production. The present study was undertaken to evaluate whether 1 has antinociceptive properties in models of inflammatory pain and to investigate its possible mechanisms of action.
Cristiane Metzker, de Oliveira   +7 more
openaire   +2 more sources

Neurotensin-induced antinociception in mice: antagonism by thyrotropin-releasing hormone

open access: yes, 1981
Neurotensin (NT), administered intracisternally to mice, produced significant dose-dependent antinociception in three analgesic tests: tail immersion, hot-plate and acetic acid writhing. Naloxone (1-5 mg/kg), an opiate antagonist administered i.p. 20 min
Nemeroff, C B   +4 more
core   +3 more sources

Investigation into atropine‐induced antinociception [PDF]

open access: yesBritish Journal of Pharmacology, 1990
The effect of atropine on the nociceptive system was examined in mice and rats by use of the hot‐plate, writhing and tail‐flick tests.Atropine dose‐dependently produced analgesia, no effect and hyperalgesia. Analgesia was observed in both species with doses ranging from 1 to 100 μg kg−1while hyperalgesia was obtained with 5 mg kg−1.Atropine ...
GHELARDINI, CARLA   +4 more
openaire   +3 more sources

Isobolographic Antinociception of Nonsteroidal Anti-inflammatory Drugs in Rodent Formalin Orofacial Pain

open access: yesPharmaceutical and Biomedical Research, 2020
Background: Diverse studies suggest that non-steroidal anti-inflammatory drugs (NSAIDs) induce antinociception through the inhibition of cyclooxygenases.
Viviana Noriega   +6 more
doaj   +1 more source

Additive interaction of intrathecal ginsenosides and neostigmine in the rat formalin test [PDF]

open access: yesKorean Journal of Anesthesiology, 2013
BackgroundThe authors evaluated the effect of intrathecal mixture of ginsenosides with neostigmine on formalin-induced nociception and made further clear the role of the spinal muscarinic (M) receptors on the activity of ginsenosides.MethodsA catheter ...
Cheon-Hee Park   +3 more
doaj   +1 more source

The antinociceptive effect of esmolol [PDF]

open access: yesKorean Journal of Anesthesiology, 2010
Esmolol is the first intravenous, short-acting, titratable β-blocker available for use in critical care and surgical settings [1]. Esmolol is thought to be a "jack of all trades" among drugs used in anesthesia because it prevents and treats cardiovascular responses due to perioperative stimuli.
openaire   +3 more sources

Antinociceptive, Sedative and Excitatory Effects of Intravenous Butorphanol Administered Alone or in Combination with Detomidine in Calves: A Prospective, Randomized, Blinded Cross-Over Study

open access: yesAnimals, 2023
(1) Background: The diagnostic and therapeutic procedures performed under sedation or general anesthesia in bovines are numerous. The analgesic drugs that can be legally used are few, making perioperative analgesia challenging.
Ekaterina Gámez Maidanskaia   +4 more
doaj   +1 more source

Antinociceptive Effect of Hydroxydihydrocarvone

open access: yesBiological and Pharmaceutical Bulletin, 2008
Hydroxydihydrocarvone (HC) is a synthetic intermediate obtained from R-(-)-carvone hydration. Due to the chemical and structural similarity between HC and other monoterpenes with psychopharmacological activity, this study was carried out to investigate the possible central antinociceptive effect of intraperitoneally administered HC, and to evaluate its
Oliveira, Fernando de Sousa   +2 more
openaire   +2 more sources

The Contribution of Gi/o Protein to Opioid Antinociception in an Oxaliplatin-Induced Neuropathy Rat Model

open access: yesJournal of Pharmacological Sciences, 2014
.: Oxaliplatin is a chemotherapeutic agent that induces chronic refractory neuropathy. To determine whether opioids effectively relieve this chronic neuropathy, we investigated the efficacies of morphine, oxycodone, and fentanyl, and the mechanisms ...
Tomoe Kanbara   +9 more
doaj   +1 more source

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