Results 1 to 10 of about 60,641 (297)

Can Antinuclear Antibodies (ANA) be Monoclonal? [PDF]

Case Reports in Nephrology, 2021
Background. Nuclear staining by immunofluorescence in a kidney biopsy is often seen in patients with positive antinuclear antibodies (ANA) in the serum. These ANA are usually polyclonal, but herein we report 9 cases with an unusual finding of monoclonal ...
Laura Biederman, Anjali A. Satoskar, Mohankumar Doraiswamy, Samir Parikh, Brad Rovin, Brian Mussio, Galina Mikhalina, Sergey V. Brodsky   +7 more
doaj   +2 more sources

A study of clinical manifestations and their association with antinuclear antibodies in various autoimmune connective tissue disorders

Indian Journal of Dermatology, 2023
Background: Autoimmune connective tissue diseases (AICTD) present with a myriad of clinical manifestations, including cutaneous. These disorders occur because of immune dysregulation that produces autoantibodies targeting connective tissue and internal ...
Rupa D Kondeti, K Venkatesh, D. V S. B Rama Murthy, Swapna Kameti, K Sri Devi, K V Chandrika   +5 more
doaj   +2 more sources

Association Between SARS-CoV-2 Vaccination and Development of Antinuclear Antibodies Among Students [PDF]

Journal of Primary Care & Community Health
Introduction: Antinuclear antibodies (ANA) are the hallmark of many connective tissue disorders (including lupus), which comprise roughly 5% to 10% of chronic debilitating diseases causing morbidity and mortality.
Karol Laskowski, Justyna Paszkiewicz, Dorota Plewik, Adam Szepeluk, Kamil K. Hozyasz   +4 more
doaj   +2 more sources

Significance of antinuclear antibodies in patients with COVID-19 [PDF]

The Korean Journal of Internal Medicine, 2023
Oh-Hyun Cho
doaj   +2 more sources

Diagnostic and Clinical Value of Specific Autoantibodies against Kelch-like 12 Peptide and Nuclear Envelope Proteins in Patients with Primary Biliary Cholangitis

Biomedicines, 2022
Primary biliary cholangitis (PBC) is a chronic autoimmune liver disease characterized by the presence of antimitochondrial and antinuclear antibodies in patients’ serum.
Alicja Bauer, Andrzej Habior, Damian Gawel   +2 more
doaj   +1 more source

Antimitochindrial and antinuclear antibodies in primary biliary cholangitis [PDF]

Ķazaķstannyṇ Klinikalyķ Medicinasy, 2019
In this work we reviewed the key antimitochondrial and antinuclear antibodies in primary biliary cholangitis – an autoimmune cholestatic disorder with destruction of intralobular biliary ductules.
Dana Saipiyeva, Manarbek Askarov, Turlybek Tuganbekov, Kulsara Rustemova, Vladimir Grigorevsky, Gulmira Dossatayeva, Nina Tostanovskaya   +6 more
doaj   +1 more source

Complement Activation in Patients With Probable Systemic Lupus Erythematosus and Ability to Predict Progression to American College of Rheumatology-Classified Systemic Lupus Erythematosus. [PDF]

, 2020
ObjectiveTo evaluate the frequency of cell-bound complement activation products (CB-CAPs) as a marker of complement activation in patients with suspected systemic lupus erythematosus (SLE) and the usefulness of this biomarker as a predictor of the ...
Alexander, Roberta Vezza, Arriens, Cristina, Collins, Christopher E, Dervieux, Thierry, Kalunian, Kenneth C, Massarotti, Elena M, Narain, Sonali, O'Malley, Tyler, Putterman, Chaim, Ramsey-Goldman, Rosalind, Saxena, Amit, Wallace, Daniel J, Weinstein, Arthur   +12 more
core   +2 more sources

Antimelanocyte antibodies: A possible role in patients with vitiligo

Indian Journal of Dermatology, 2020
Background: Vitiligo is an acquired depigmenting skin disorder with multifactorial pathogenesis including genetic, autoimmune, and neuronal factors. Both humoral- and cell-mediated immunities are supposed to have a role in the pathogenesis of vitiligo ...
Maha A El-Gayyar, Manal E Helmy, Eman R Amer, Moustafa A Elsaied, Mohammad A Gaballah   +4 more
doaj   +1 more source

Do we need broad immunological work-up in all patients with CIS? [PDF]

, 2012
BACKGROUND: The aim of this study was to determine the prevalence of altered immunological tests and their clinical significance in patients with clinically isolated syndrome (CIS) suggestive of multiple sclerosis (MS). ----- PATIENTS AND METHODS:
Adamec, Ivan, Bošković, Mateja, Gabelić, Tereza, Habek, Mario, Posavec, Vanja, Radmilović, Marin, Škvorc, Ana   +6 more
core   +1 more source

Belimumab : a technological advance for systemic lupus erythematosus patients? Report of a systematic review and meta-analysis [PDF]

, 2013
Objectives: To undertake a systematic review and meta-analysis to investigate clinical effectiveness of belimumab for patients with systemic lupus erythematosus (SLE) and antinuclear and/or anti-double-stranded DNA (dsDNA) autoantibodies.
Clarke, Aileen, Connock, M., Court, Rachel A., Cummins, E., Gordon, Caroline, Grove, Amy L., Hartley, Louise, Kandala, Ngianga-Bakwin, Mohiuddin, Syed, Sutcliffe, P. (Paul)   +9 more
core   +1 more source