Failure to achieve lupus low disease activity state (LLDAS) six months after diagnosis is associated with early damage accrual in Caucasian patients with systemic lupus erythematosus [PDF]
, 2017 Background: The aim was to assess the attainability and outcome of the lupus low disease activity state (LLDAS) in the early stages of systemic lupus erythematosus (SLE).
CAPPELLAZZO, GIULIA +6 more
core +1 more source
Rheumatology, 2018 The presence of antinuclear antibodies (ANA) is mainly associated with connective tissue diseases (CTD). In addition, their presence is found in healthy people. These antibodies are more common in women and the elderly.
B. Grygiel-Górniak +2 more
semanticscholar +1 more source
Drug-like analogues of the parasitic worm-derived immunomodulator ES-62 are therapeutic in the MRL/Lpr model of systemic lupus erythematosus [PDF]
, 2015 Introduction ES-62, a phosphorylcholine (PC)-containing immunomodulator secreted by the parasitic worm Acanthocheilonema viteae, protects against nephritis in the MRL/Lpr mouse model of systemic lupus erythematosus (SLE).
Harnett, M. M. +4 more
core +1 more source
Autoimmune diseases and their manifestations on oral cavity: diagnosis and clinical management [PDF]
, 2018 Oral signs are frequently the first manifestation of autoimmune diseases. For this reason, dentists play an important role in the detection of emerging autoimmune pathologies.
Bossù, Maurizio +5 more
core +2 more sources
Diagnostic Pathology, 2009 It has been more than 50 years since antinuclear antibodies were first discovered and found to be associated with connective tissue diseases. Since then different methods have been described and used for their detection or confirmation.
Minz Ranjana +2 more
doaj +1 more source
Negative association of the chemokine receptor CCR5 d32 polymorphism with systemic inflammatory response, extra-articular symptoms and joint erosion in rheumatoid arthritis [PDF]
, 2009 Introduction Chemokines and their receptors control immune cell migration during infections as well as in autoimmune responses. A 32 bp deletion in the gene of the chemokine receptor CCR5 confers protection against HIV infection, but has also been ...
Arnold, Sybille +6 more
core +2 more sources
Antinuclear antibodies in systemic sclerosis associated with increased risk of malignancy
Przegląd Dermatologiczny, 2018 Patients with systemic sclerosis are at 1.5–5-fold increased risk of developing malignant diseases. It has been shown that some types of antinuclear antibodies associated with systemic sclerosis may have predictive value for development of malignant ...
Anna Stochmal +3 more
doaj +1 more source
Immunology markers that can be predictive for the diagnosis of juvenile idiopathic arthritis
Journal of Laboratory Medicine, 2020 This study aimed to investigate the implications of antinuclear antibodies (ANAs) in juvenile idiopathic arthritis (JIA), the association with uveitis and the favorable evolution of the disease.
Sur Lucia M. +9 more
doaj +1 more source
Antinuclear antibody profiling in uveitis [PDF]
Acta Ophthalmologica, 2018 _Editor,_ Antinuclear antibodies (ANA) are antibodies directed against a variety of nuclear antigens and are detected in patients with autoimmune diseases. Antinuclear antibodies (ANA) profiling is relevant for diagnostic purposes in various diseases, including systemic lupus erythematosus (SLE), Sj€ogren syndrome and systemic sclerosis (Smeenk et ...
Josianne C. ten Berge +3 more
openaire +4 more sources
Antinuclear antibodies by indirect immunofluorescence and solid phase assays
Annals of the Rheumatic Diseases, 2019 Pisetsky et al recently reported substantial variability between two antinuclear antibodies (ANA) indirect immunofluorescence (IIF) assays as well as one solid-phase assay (SPA) from different manufacturers in a study of a cross-sectional cohort of ...
X. Bossuyt +9 more
semanticscholar +1 more source