Results 61 to 70 of about 45,060 (217)

Multifunctional Manganese Oxide Nanocomposite Hydrogel With Synergistic Reactive Oxygen Species‐Scavenging, Oxygen‐Generating, Immunomodulatory, and Photothermal Antimicrobial Activities for Enhanced Diabetic Wound Healing

Advanced Science, EarlyView.
CFP/PC@MnO2 hydrogel integrates ROS scavenging, oxygen delivery, oxidative stress reduction, immunomodulation, and photothermal antibacterial properties. The incorporation of PC@MnO2 NPs endows the hydrogel with multiple functional advantages tailored to the pathological microenvironment of diabetic wounds, including efficient ROS clearance, mitigation
Zhi Xu, Xiaodong Luo, Jingxian Wu, Chaoyang Huang, Zhuoying Yang, Yixiang HePeng, Bosong Zhou, Xiang Li, Ruiyuan Liu, Xu Wu   +9 more
wiley   +1 more source

Characterization and bioactivities of a novel copper–zinc superoxide dismutase from the marine snail Rapana venosa: antioxidant, antimicrobial, and anticancer effects

Beni-Suef University Journal of Basic and Applied Sciences
Background Marine organisms, particularly snails, are rich sources of bioactive compounds with potential antioxidant, antimicrobial, and anticancer properties, offering promising avenues for drug discovery.
Mai A. Saleh, Mohamed R. Habib, Sherif R. AbdElGhany, Mohamed Fathy Abouel-Nour, Hassan M. M. Masoud   +4 more
doaj   +1 more source

Innovative Test Strip‐Based Colorimetric Sensors Integrated With Affinity Chromatography: Acetylcholinesterase Inhibitor Screening Breakthrough in Lycium Barbarum Leaves

Advanced Science, EarlyView.
Schematic diagrams illustrating the breakthrough in the screening of AChE inhibitors from LBL, and the research process of the pharmacodynamics of the NCP are presented. ABSTRACT Current Alzheimer's drugs exhibit limited effectiveness, highlighting the necessity for multi‐target treatments.
Yuping Sa, Hui Yuan, Jingui Ma, Zhigang Yang, Mei Wang, Weibiao Wang, Lingling Yang, Fen Ma, Weiman Zhang, Gidion Wilson Mening'oo, Guoning Chen, Xueqin Ma   +11 more
wiley   +1 more source

Enzyme inhibitory, antioxidant, antimicrobial activities, and phenolic profiles of the methanol extract of Gelasia sericea an endemic species

Notulae Botanicae Horti Agrobotanici Cluj-Napoca
This study aimed to investigate, for the first time, the phytochemical composition, antioxidant, antimicrobial, and enzyme inhibitory properties of the methanolic extract of Gelasia sericea (Aucher ex DC.) Zaika, Sukhor. & N.Kilian.
İmdat AYGÜL, Osman AKMEŞE, Abdurrahman SEFALI, Cemalettin BALTACI, Mehmet ÖZ, Muhammed Said FIDAN   +5 more
doaj   +1 more source

Pharmacological activities of leaf and bark extracts of a medicinal mangrove plant Avicennia officinalis L.

Clinical Phytoscience, 2018
Background Avicennia officinalis is a medicinally important mangrove plant and used in traditional medicinal practices to treat various ailments like rheumatism, paralysis, asthma, dyspepsia, tumors etc. The objective of the present study was to evaluate
Swagat Kumar Das, Dibyajyoti Samantaray, Archana Mahapatra, Nityasundar Pal, Rudranarayan Munda, Hrudayanath Thatoi   +5 more
doaj   +1 more source

Rhoifolin Alleviates Ulcerative Colitis by Targeting NMNAT1 and Activating SIRT1‐FOXO1 Signaling to Enhance ILC3s Effector Function

Advanced Science, EarlyView.
Rhoifolin directly targets NMNAT1, thereby activating nicotinamide salvage pathway and promoting intracellular NAD+ biosynthesis. Elevated NAD+ levels enhance SIRT1 activity, leading to FOXO1 deacetylation and nuclear translocation. Nuclear FOXO1 subsequently binds to the IL‐22 promoter, upregulating IL‐22 transcription and potentiating ILC3 effector ...
Hongqiong Yang, Yishu Zhang, Sijia Feng, Xiaoqing Ma, Jiayi Feng, Junwei Wang, Jialin Gao, An Pan, Dapeng Wu, Kang Ding, Caijuan Zheng, Qi Lv, Lihong Hu   +12 more
wiley   +1 more source

GC-MS, quantitative phytochemical estimation and biological activities of the leaf and root extracts of Ficus racemosa L․

Pharmacological Research - Modern Chinese Medicine
Introduction: Ficus racemosa L. (Jù guǒ róng) is a traditionally used medicinal plant in the management of various ailments, including diabetes, dysentery, bilious affections, diarrhea, etc.
Shikha Dhiman, Priyanka Sharma, Jyoti Rana, Amit Kumar Sehgal   +3 more
doaj   +1 more source

A pH‐Switchable Cerium Single‐Atom Enzyme for Peri‐Implantitis Therapy via JAK‐STAT Signaling Axis‐Mediated Macrophage Reprogramming

Advanced Science, EarlyView.
A pH‐switchable cerium single‐atom enzyme is developed for stage‐specific peri‐implantitis therapy. Acidic conditions trigger antibacterial peroxidase‐like activity, whereas neutral conditions activate an antioxidant superoxide dismutase ‐ and catalase ‐like enzymatic relay. This microenvironment‐adaptive catalytic strategy suppresses the IL‐6/JAK‐STAT
Xiaomin Xia, Haojie Wu, Xingyun Li, Lining Liu, Kaiqing Song, Jinpei Cui, Jie Liu, Jiaxuan Yin, Emtiaz Ahmed, Yusuke Yamauchi, Xue Li   +10 more
wiley   +1 more source

Programmed Interfacial Phase Separation for Spatiotemporal Fungicide Delivery via Tunable Micro/Nano Architectures

Advanced Science, EarlyView.
ABSTRACT Translating dynamic liquid‐liquid phase separation into robust solid‐state architectures remains a challenge in materials engineering. Here, we report a composition‐driven interfacial assembly strategy that couples supramolecular coacervation with metal‐phenolic coordination to engineer tunable fungicide carriers.
Rui Zhang, Tongfang Jing, Leiming He, Kaidi Cui, Yuying Song, Xuewei Mao, Lidong Cao, Lin Zhou   +7 more
wiley   +1 more source

Exploring phytochemical and biological profile of Adiantum aleuticum (Western maidenhair fern); an indigenous fern with medicinal potential

Results in Chemistry
Introduction: Adiantum aleuticum (A. aleuticum) belongs to a medicinally important genus Adiantum. Different species of genus Adiantum are traditionally used as anti-diabetic, analgesic, anti-inflammatory, and antifungal remedy. A.
Huma Rao, Saeed Ahmad, Muhammad Zeeshan, Maahpara Laiq, Abdul Basit, Sidra Iqbal, Imran Hussain, Syeda Sumayya Tariq, Zaheer Ul-Haq   +8 more
doaj   +1 more source