Results 71 to 80 of about 1,062,799 (328)

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

open access: yesMolecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella   +18 more
wiley   +1 more source

Assay of the antioxidant capacity of foods using an iron(II)-catalysed lipid peroxidation model for greater nutritional relevance [PDF]

open access: yes, 2010
The formation of free radicals by the iron-catalysed Fenton reaction is a major cause of oxidative damage in the body. Here a common assay of antioxidant capacity, inhibition of the β-carotene-linoleic acid model of lipid peroxidation, has been modified ...
Brangoulo, Helene L., Molan, Peter C.
core   +2 more sources

Antioxidant activity of phenolic compounds

open access: yesGrasas y Aceites, 1993
This review deals with the oxidation processes induced by light and atmospheric oxygen, as well as the protective action on antioxidant compounds. The available data on the synthetic antioxidants and the problems associated to their use, together with ...
R. Maestro Durán, R Borja Padilla
doaj   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

A Brief Overview on Antioxidant Activity Determination of Silver Nanoparticles

open access: yesMolecules, 2020
Our objective in this review article is to find out relevant information about methods of determination of antioxidant activity of silver nanoparticles.
Zdenka Bedlovičová   +3 more
doaj   +1 more source

Gut alterations in a chronic kidney disease rat model with diet‐induced vascular calcification

open access: yesFEBS Open Bio, EarlyView.
Chronic kidney disease (CKD) patients often suffer from intestinal and/or mineral and bone disorders. Using a rat model, we showed that uremic vascular calcification is associated with gut barrier alterations (decreased gut mucus production and Nlrp6 gene expression, increased gut inflammation), and plasma retention of gut‐origin uremic toxins (indoxyl
Piotr Bartochowski   +13 more
wiley   +1 more source

Antioxidant activity, photosynthetic rate, and Spectral mass in bean Plants (Phaseolus vulgaris L.) in Response to Stress Defense Activators [PDF]

open access: yes, 2018
An increase in antioxidant activity is a common response in plants as a defense mechanism against biotic and abiotic stress factors, such response is also generated with the exogenous application of "defense activators", which have negative effects on ...
Castillo, F. D. (Francisco)   +6 more
core  

Antioxidant and antihemolytic activities of methanol extract of Hyssopus angustifolius [PDF]

open access: yes, 2012
This study was designed to evaluate antioxidant and antihemolytic activities of Hyssopus angustifolius flower, stem and leaf methanol extracts by employing various in vitro assays.
Alinezhad, H.   +6 more
core   +3 more sources

Antioxidant Activity of Ethanol Extract of Polygonum pulchrum Blume

open access: yesPharmacology and Clinical Pharmacy Research, 2016
The use of antioxidants from natural resources has attracted increasing interest. One of the plant that was empirically used as an antioxidant dietary supplement was Polygonum pulchrum Blume (P. pulchrum Blume).
Asman Sadino   +2 more
doaj   +1 more source

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

open access: yesFEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna   +4 more
wiley   +1 more source

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