Results 91 to 100 of about 3,164,858 (304)

Targeting CD300a Signaling With a Phosphatidylserine‐Presenting Hydrogel Rescues Macrophage Dysfunction and Accelerates Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Schematic illustration of the proposed mechanism: PEG/RGD‐PSLs mimic apoptotic cells to engage PS receptors (notably CD300a), transducing an inhibitory signal that suppresses the MyD88/NF‐κB pathway, leading to global anti‐inflammatory and pro‐reparative effects.
Lele Wu, Xuetong Hao, Yang Zou, Xinglin Chen, Junyan Kong, Chunning Gu, Wenjie Ma, Zhongjun Yang, Huifen Liu, Mengmeng Liu, Xin Tong   +10 more
wiley   +1 more source

Comparative study of total phenolic content and radical scavenging activity of conventionally and organically grown herbs [PDF]

, 2010
The aim of the present study was to measure the relative phenolic content in commonly available conventionally and organically grown herbs and to evaluate their antioxidant capacity.
Todorova, M., Vassileva, Elka, Ivanova, Daniela, Trendafilova, A.   +3 more
core   +1 more source

PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao, Lin Gan, Li Lu, Lizhi Ouyang, Yuan Xiong, Fawwaz Al‐Smadi, Guandong Dai, Mohammad‐Ali Shahbazi, Bobin Mi, Mengfei Liu, Guohui Liu   +10 more
wiley   +1 more source

Correlation between antioxidant capacity and anti-inflammatory capacity: a case study of six standard antioxidants

Open Chemistry
Oxidation is a significant contributor to inflammatory responses. However, the association between antioxidant capacity and anti-inflammatory capacity of antioxidants is unclear.
Chen Chih-Jung, Liao Yi-Jing, Chen Cheng-You, Chen Yu-Chun, Huang Tsung-Tao, He Cheng-Kun, Lin Yung-Sheng   +6 more
doaj   +1 more source

Antioxidant Properties of Peanut Plant Leaves and Roots and Contribution of Specific Phenolic Compounds to Antioxidant Capacity

, 2007
The peanut seeds represent less than 40 % of the total biomass of the peanut plant. Currently, peanut plants are left in the field after harvest or baled for animal feed. The research presented here was the second step in identifying bioactive compounds
Simpson, Joy Anna
core  

An Engineered Biomimetic Nanoreactor With Cascade Functions for Targeted and Combinatorial Therapy of Ischemic Stroke

Advanced Healthcare Materials, EarlyView.
Preparation of RVG‐modified erythrocyte membrane‐coated HMPB nanocarriers loaded with L‐arginine and NBP (RM@HPAN) and its neuroprotective mechanism. After intravenous injection, RM@HPAN achieves prolonged circulation, RVG‐29‐mediated BBB penetration, and ischemic accumulation.
Shaofa Li, Ying Wu, Huimin Wei, Jinyong Teng, Zaizhi Yang, Jufang Chen, Bao Liao, Xiaoqin Huang, Lanqing Meng, Tong Li   +9 more
wiley   +1 more source

Illustrative Quotes, Interview Guide and Information Sheets for: Developing laboratory capacity for Good Laboratory Practice certification: lessons from a Tanzanian insecticide testing facility

Interview guide used across 5 test facilities in 3 African countries to explore enablers, barriers and effects of a research capacity strengthening programme, targeting development of a Quality Management System compliant with Good Laboratory Practice ...
Capacity Research, Centre for
core   +1 more source

Lignin Mimicking Protein Methylation Augments the Efficacy of FOLFOX Chemotherapy by Anchoring Thymidylate Synthase

Advanced Materials, EarlyView.
Lignin‐mimicking protein methylation can enhance the efficacy and mitigate the toxicity of the classic FOLFOX chemotherapy regimen. ABSTRACT FOLFOX has served as the standard chemotherapy regimen for advanced stages, specifically in the treatment of pancreatic, colorectal, and bladder cancers.
Shiyao Song, Yan‐Lai Tang, Xiaoting Liu, Jiayi Zheng, Chong Wu, Tang Li, Junhong Ye, Dianmin Xia, Yong Mei, Jingxuan Ma, Libin Huang, Xuequn Luo, Liheng Chen, Yanlin Qin, Weiling He   +14 more
wiley   +1 more source

Bioactive compounds and antioxidant capacity of fruit on Sechium edule [PDF]

, 2010
Vegetables and fruits contain bioactive compounds with antioxidant activity such as phenols and flavonoids, carotenoids, ascorbate, alimentary fiber, selenium and many substances with antiatherogenics and anticarcinogenics properties. The purpose of this
Albarracin, Graciela, Marchevsky, Eduardo Jorge, Escudero, Nora Lilian, Lucero López, Viviana Romina   +3 more
core   +1 more source

Soy protein with and without isoflavones fails to substantially increase postprandial antioxidant capacity.

, 2012
[[abstract]]Five methods for the assessment of antioxidant capacity [whole plasma conjugated diene formation, low-density lipoprotein oxidation susceptibility, ferric-reducing ability of plasma, oxygen radical absorbance capacity and perchloric-acid ...
張竣維;Hebron, C.Chang
core