Results 131 to 140 of about 13,218,886 (306)

Flexible and Scalable 2D/3D Tin‐Based Perovskite Photodetectors via Inkjet Printing

open access: yesAdvanced Optical Materials, EarlyView.
Lead‐free tin‐based perovskite films are successfully fabricated via scalable inkjet printing on rigid and flexible substrates. Incorporating high‐purity precursors and dual‐layer encapsulation minimizes defects and eliminates oxidation. The resulting photodetectors demonstrate high responsivity, persistent photoconductivity, and excellent 30 day ...
Giovanni Vescio   +13 more
wiley   +1 more source

Effects of glucose oxidase on growth performance, immunity, and antioxidant function of yellow feather broilers

open access: yesSiliao yanjiu
The experiment aimed to investigate the effects of glucose oxidase on the growth performance, immunity, and antioxidant function of yellow feather broilers.
SUN Liuxia   +4 more
doaj  

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

open access: yesAdvanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu   +8 more
wiley   +1 more source

Effects of fermented Chinese herbal medicine on reproductive performance, serum biochemical parameters, immune function, and antioxidant function of pregnant sows

open access: yesSiliao yanjiu
This study aimed to investigate the effects of fermented Chinese herbal medicine on the reproductive performance, serum biochemical parameters, immune function, and antioxidant function of pregnant sows.
LAN Zhibin   +5 more
doaj  

Agnuside Stabilizes the Complex I Assembly Factor NDUFAF6 to Reinforce Mitochondrial Efficiency and Thermogenic Responsiveness

open access: yesAdvanced Science, EarlyView.
ABSTRACT Brown and beige adipocytes dissipate energy as heat, yet effective strategies to enhance their mitochondrial efficiency remain limited. Here, we identify Agnuside (AGN) as a selective stabilizer of the complex I assembly factor NDUFAF6. AGN directly binds cytosolic NDUFAF6, suppresses its ubiquitination, prolongs its half‐life, and facilitates
Qingwen Zhao   +7 more
wiley   +1 more source

Effects of Forsythia suspensa fruit powder on growth performance, inflammatory factor levels, immune indicators, antioxidant function, and muscle metabolomics in meat geese

open access: yesSiliao yanjiu
This experiment aimed to investigate the effects of Forsythia suspensa fruit powder on the growth performance, inflammatory factor levels, immune indicators, antioxidant function, and muscle metabolomics in meat geese. A total of 192 healthy Sanhua geese
LIU Yaoxi   +5 more
doaj  

Phosphorylation‐Facilitated CKB Lactylation At K11 By GCN5 Enhances Creatine Kinase Activity and Mitigates Neuronal Damage After Cerebral Ischemia‐Reperfusion

open access: yesAdvanced Science, EarlyView.
This study uncovers hierarchical coordination between K11 lactylation and S199 phosphorylation of CKB in cerebral ischemia‐reperfusion injury. Such dual modifications potentiate CKB enzymatic function, remodel energy metabolism, alleviate oxidative stress and neuronal damage, and represent a viable therapeutic target for stroke treatment.
Chao Duan   +17 more
wiley   +1 more source

Canagliflozin Alleviates Diabetic Glomerular Endothelial Injury via Melibiose in a Microbiota‐Dependent Manner

open access: yesAdvanced Science, EarlyView.
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang   +32 more
wiley   +1 more source

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

open access: yesAdvanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green   +15 more
wiley   +1 more source

Mitochondrial Dysfunction Unravels the Potential Molecular Link Between Night Shift Work‐Related Circadian Disruption and Elevated Blood Pressure in Human and Mouse Models

open access: yesAdvanced Science, EarlyView.
This diagram illustrates that night shift work disrupts circadian clock genes (like CLOCK, BMAL1) in both humans and mice. This disruption leads to mitochondrial dysfunction (imbalanced fusion/fission proteins) and increased oxidative stress, which is identified as the primary mechanism ultimately causing elevated blood pressure.
Zhaoqiang Jiang   +16 more
wiley   +1 more source

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