Results 151 to 160 of about 13,218,886 (306)

TME/NIR Dual‐Responsive Zinc‐Based Targeted Nanoagonist for Multimodal Amplification of STING‐Mediated Cancer Immunotherapy

Advanced Science, EarlyView.
A multifunctional nanoagonist (cDZ@IP) enables nano‐metabolite–driven multimodal activation of the STING pathway and enhanced immune recognition, achieving potent antitumor immunity and suppressing tumor growth and metastasis. This strategy highlights the rational design of therapeutic metabolites and establishes a new paradigm bridging nanomedicine ...
Kepeng Hu, Jiawei Wang, Wei Zhang, Zhixuan Wu, Jing Chen, Yujing He, Xiyue Duan, Yaoting He, Xin Xin, Haoyi Xiang, Yijing Wang, Chengwei Wu, Yang Yi, Qing Meng, Yuqian Qiao, Kui Cheng, Xiaojun Long, Zhangfa Song   +17 more
wiley   +1 more source

Loss of antioxidant function in donor human milk after holder pasteurization: a pilot study. [PDF]

Front Nutr
Leong A, Mori C, Pillidge C, Gill H.
europepmc   +1 more source

BIN1 and ALDH1B1 Deficiency in Colonic Smooth Muscle Drives Mitochondrial Dysfunction and Fibrosis in Slow‐Transit Constipation

Advanced Science, EarlyView.
Slow‐transit constipation (STC) is a disabling motility disorder with unclear smooth‐muscle mechanisms. Spatial proteomic analysis of STC patient colon reveals both the central pathogenic role of smooth muscle cells (SMCs) in STC and novel regulators of intestinal motility, BIN1 and ALDH1B1.
Jianbo Liu, Hao Zhang, Wenhao Qiao, Ran Liu, Jie Sun, Xiaopei Li, Qin Li, Dongbo Zhao, Dawei Chen, Jingxin Li, Shuxiao Dong   +10 more
wiley   +1 more source

Effects of Supplementation with Dimethylglycine Sodium Salt on Immunity, Intestinal Tissue Morphology, and Antioxidant Function in IUGR Lambs. [PDF]

Animals (Basel)
Wang Y, Li M, Ma L, Lin Y, Zhang C, Cheng Z, Chen Y, Zang C.   +7 more
europepmc   +1 more source

Selenium Nanoparticles Selectively Target KRAS G13D to Inhibit Colorectal Cancer

Advanced Science, EarlyView.
The mechanisms of SeNPs therapy in cancer treatment, encompass three parallel actions: (1) seleno‐amino acids, key metabolites, upregulate GPX2 expression, thereby inhibiting tumor metastasis via the GPX2‐HIF1α‐VEGF signaling pathway; (2) selenite (SeO32−), an inorganic metabolite, forms hydrogen bonds with amino acid residues 13–17 of the KRAS G13D ...
Xiaoting Liu, Chong Wu, Shiyao Song, Li Ma, Shaoqing Huang, Yuting He, Qinghai Li, Yanzhou Chang, Dan Jiang, Yong Mei, Junchao Cai, Zhenshuang Du, Tianfeng Chen, Weiling He   +13 more
wiley   +1 more source

Research progress on preparation of biogenic nano-selenium and its application in aquaculture

Siliao yanjiu
Selenium (Se), as an essential trace element for aquatic animals, enhances immune function and anti-infection capacity. Nano-selenium has emerged as a promising feed additive due to its low toxicity and high bioactivity.
REN Jiayu, WANG Furong, ZHANG Yuwei, WANG Longqi, HU Ruitong, WANG Lianshun, LU Yanan, YANG Guojun   +7 more
doaj  

Alterations of Growth Performance, Blood Parameters, and Antioxidant Function of Brown Adipose Tissue in Mice Exposed to Cold. [PDF]

Antioxidants (Basel)
Zhang X, Jin X, Han Z, Jiang M, Shi B.
europepmc   +1 more source

Oral Motion‐Powered Smart Dental Implant Abutment for In Situ Antibacterial and Cell Adhesion Through Piezoelectric Effect

Advanced Science, EarlyView.
We proposed a method based on the piezoelectric effect and fabricated an implant abutment on the basis of piezoelectric ceramic. Under physiological occlusal pressure, the oral motion‐powered smart dental implant abutments interacted with water and oxygen, promoting the formation of reactive oxygen species and achieving a synergistic and highly ...
Xiyu Shi, Xiaoyu Han, Yanhui Lu, Yuan Chai, Baiyan Xiao, Shuo Liu, Boon Chin Heng, Tingting Wu, Tingjun Li, Qiaomei Ren, Ting Song, Le Chen, Dong Han, Yaru Guo, Xuliang Deng, Xuehui Zhang   +15 more
wiley   +1 more source

Effects of Artemisia argyi powder on production performance， egg quality， antioxidant function， and fecal scores of laying hens

Siliao yanjiu
This experiment aimed to investigate the effects of Artemisia argyi powder on the production performance, egg quality, antioxidant function, and fecal scores of laying hens. A total of 1 008 Hyline brown laying hens at 35 weeks of age with similar laying
CUI Ying-cai, JIANG Meng-yu, LIU Meng-ru, LAI Jin-liang, YAO Xing-wen, WANG Zheng-guo, YAN Lei, LIU Yong-xue   +7 more
doaj  

The antioxidant function of Piper sarmentosum Roxb. alcoholic extract in heat-stressed broilers. [PDF]

Poult Sci
Abouelezz K, Zhou L, Sayed MAM, Hassan AK, Elokil A, Abdelmalek AM, Omar WA, Ali EF, Hou G, Wang D.   +9 more
europepmc   +1 more source