Results 161 to 170 of about 13,218,886 (306)

Mitochondrial SLC25A46 Rewires Fatty Acid Oxidation to Promote Cell Proliferation and Ferroptosis Evasion in Ovarian Cancer by Stabilizing CACT

open access: yesAdvanced Science, EarlyView.
Mitochondrial SLC25A46 is upregulated in ovarian cancer (OC) and correlates with poor prognosis. SLC25A46 stabilizes CACT to activate fatty acid oxidation, increasing ATP and NADPH production to drive cell proliferation and ferroptosis evasion. SLC25A46 silencing sensitizes OC cells to ferroptosis and carboplatin, offering a promising therapeutic ...
Yunge Gao   +9 more
wiley   +1 more source

Effects of different levels of composite probiotic preparations on growth performance, immune function, antioxidant function, and rumen flora of fattening Hu sheep

open access: yesSiliao yanjiu
The experiment aimed to investigate the effects of different levels of compound probiotic preparations on the growth performance, immune function, antioxidant function, and rumen flora of fattening Hu sheep.
ZHU Yixiao   +4 more
doaj  

Optimized Ex Vivo Human Liver Slice Culture Maintains Extended Viability and Function for Hepatotoxicity Testing

open access: yesAdvanced Science, EarlyView.
An optimized ex vivo human liver slice culture system preserves tissue architecture, hepatocyte function, and immune‐stromal complexity for at least five days. By refining slice thickness, oxygenation, air‐liquid interface, and extracellular matrix support, the platform enables human‐relevant hepatotoxicity testing and mechanistic studies, offering a ...
Huiche Feng   +17 more
wiley   +1 more source

Celastrol‐Loaded Conductive Hydrogel Mitigates Myocardial Ischemia‐Reperfusion Injury and Restores Electrophysiological Function

open access: yesAdvanced Science, EarlyView.
Schematic illustration of the Pluronic F127 diacrylate/gelatin methacryloyl/poly(3,4‐ethylenedioxythiophene):poly(styrenesulfonate)/celastrol hydrogel (FGPC) for localized myocardial ischemia–reperfusion injury treatment. FGPC combines sustained celastrol delivery with PEDOT:PSS‐mediated conductive support to attenuate acute oxidative/inflammatory ...
Shixin Wang   +10 more
wiley   +1 more source

Thioredoxin reductase from Toxoplasma gondii: an essential virulence effector with antioxidant function

open access: yesThe FASEB Journal, 2017
Junxin Xue   +8 more
semanticscholar   +1 more source

Study on effects of COS and RPAA on rumen fermentation, nutrient degradation, and antioxidant function of dairy cows under a low-protein diet by in vitro three-step method

open access: yesSiliao yanjiu
The experiment aimed to explore the effects of chitosan (COS) and rumen-protected amino acids (RPAA) on in vitro rumen fermentation, nutrient degradation rates, and antioxidant function of dairy cows under low-protein diets by the in vitro three-step ...
GUO Yongmei   +7 more
doaj  

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