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Antioxidant function of metallothioneins
The Journal of Trace Elements in Experimental Medicine, 1998Since the discovery of metallothionein in 1957, it has been accepted that the primary roles of this protein are: 1) detoxification of heavy metals, and 2) regulation of the metabolism of essential metals. Recently, studies have suggested an additional role for metallothionein as a free radical scavenger.
Kelley Kiningham, Edward Kasarskis
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Functions of Antioxidant Vitamins beyond RDAs
2001Chemicals/CAS: Antioxidants ...
Diplock, A.T., Poppel, G. van
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Phenolic antioxidants-functionalized quaternized chitosan: Synthesis and antioxidant properties
International Journal of Biological Macromolecules, 2013In this work, two kinds of phenolic antioxidants-functionalized quaternized chitosan were synthesized in order to develop aqueous soluble antioxidant-polymer conjugates. Quaternized chitosan conjugated with gallic acid or caffeic acid was carried out and the antioxidant properties of the products (namely gallic acid-quaternized chitosan and caffeic ...
Jianming, Ren +4 more
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The Antioxidant Function of Metallothionein in the Heart
Proceedings of the Society for Experimental Biology and Medicine, 1999Abstract.The antioxidant function of metallothionein (MT) was first suggested in the early 1980s. Studies in vitro have revealed that MT reacts directly with reactive oxygen species, including superoxide and hydroxyl radicals and hydrogen peroxide. These reactions have never been demonstrated in intact animal studies.
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Caroverine, a multifunctional drug with antioxidant functions
BioFactors, 2003AbstractHere we show that lipid peroxidation of liposomal membranes was suppressed in the presence of Caroverine, a spasmolytic drug used in some countries. In order to understand the mechanism of this antioxidant action of Caroverine we studied the interaction of Caroverine with superoxide radicals, hydroxyl radicals and peroxynitrite.
Hans, Nohl +4 more
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Antioxidants in functional foods
Journal of Food Biochemistry, 2022Apollinaire Tsopmo, Farah Hosseinian
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Prion Disease: A Loss of Antioxidant Function?
Biochemical and Biophysical Research Communications, 2000Prion disease, a neurodegenerative disorder, is widely believed to arise when a cellular prion protein (PrP(C)) undergoes conformational changes to a pathogenic isoform (PrP(Sc)). Recent data have shown PrP(C) to be copper binding and that it acquires antioxidant activity as a result. This enzymatic property is dependent mainly on copper binding to the
B S, Wong +8 more
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Vitamin E: beyond antioxidant function
The American Journal of Clinical Nutrition, 1995Vitamin E, a potent peroxyl radical scavenger, is a chain-breaking antioxidant that prevents the propagation of free radical damage in biological membranes. We consider the evidence for potential sites in cellular metabolism and signal transduction where vitamin E may have a structure-specific role in addition to its antioxidant function.
M G, Traber, L, Packer
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Novel function of VEGF‐B as an antioxidant and therapeutic implications
Pharmacological Research, 2019&NA; Oxidative stress, due to insufficiency of antioxidants or over‐production of oxidants, can lead to severe cell and tissue damage. Oxidative stress occurs constantly and has been shown to be involved in innumerable diseases, such as degenerative ...
Rongyuan Chen +4 more
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The suppression of granulocyte functions by lipophilic antioxidants
Biochemical Pharmacology, 1988The effects of several antioxidants on the three major functions of human neutrophils--oxidative burst, secretion and leukotriene formation--were investigated with special emphasis on the lipophilicity. The most striking differences were obtained when ascorbate and the lipophilic ester ascorbyl palmitate were compared.
W J, Baader, A, Hatzelmann, V, Ullrich
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