Results 71 to 80 of about 5,998,007 (252)

Isoflavone content and antioxidant properties of soybean seeds [PDF]

, 2011
The isoflavone content and antioxidant properties of five Croatian soybean seed cultivars from two locations were analysed. The content of total and individual isofavones was determined by high performance liquid chromatography.
Šertović, Edina, Jokić, Stela, Alibabić, Vildana, Vidović, Senka, Mujić, I., Živković, Jelena, Sarić, Z.   +6 more
core   +1 more source

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

FEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto, Shiori Sakai, Minori Endo, Terigele, Mizuho Niibori, Taiki Morita, Yu Goto, Arisa Yoshida, Tomohiro Tanaka, Ning Lin, Takahiro Kuchimaru, Hiroyuki Nakamura, Masahiro Inoue, Shinae Kizaka‐Kondoh, Tetsuya Kadonosono   +14 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Nutraceutical antioxidant potential and polyphenolic profiles of the Zambian market classes of bambara groundnuts (Vigna subterranea L. Verdc) and common beans (Phaseolus vulgaris L.) [PDF]

, 2013
Includes abstract.Includes bibliographical references.There is a growing interest in legumes and legume based foods because of the health claims associated with their consumption. The aim of the current study was to explore the nutraceutical potential of
Nyau, Vincent
core   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

Effect of Turmeric and Carrot Seed Extracts on Serum Liver Biomarkers and Hepatic Lipid Peroxidation, Antioxidant Enzymes and Total Antioxidant Status in Rats [PDF]

Introduction: Pathogenic role of free radicals are well known in various metabolic diseases. They originate from internal and external sources of body.
رضایی مقدم, عادل, مهاجری, داریوش, شهیدی, مریم السادات, رفیعی, بهنام, مأذنی, محمد, اظهری, اصغر, دیزجی, رعنا, یگانه زاد, مهدی   +7 more
core  

Functionality of HDL: Antioxidation and Detoxifying Effects [PDF]

, 2014
High-density lipoproteins (HDL) are complexes of multiple talents, some of which have only recently been recognised but all of which are under active investigation. Clinical interest initially arose from their amply demonstrated role in atherosclerotic disease with their consequent designation as a major cardiovascular disease (CVD) risk factor ...
Helen, Karlsson, Anatol, Kontush, Richard W, James   +2 more
openaire   +2 more sources

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Polymeric membranes with selective permeability : shielding of an antioxidant enzyme [PDF]

, 2008
In this work we designed an antioxidant nanoreactor based on the encapsulation of CuZnSOD in amphiphilic copolymer nanovesicles. The nanovesicles are formed by self-assembly of amphiphilic copolymer poly-(2-methyloxazoline)-poly- (dimethylsiloxane ...
Axthelm, Fabian
core   +1 more source

The universal soldier: enzymatic and non-enzymatic antioxidant functions of serum albumin. [PDF]

, 2020
open access articleAs a carrier of many biologically active compounds, blood is exposed to oxidants to a greater extent than the intracellular environment.
Anastasia A. Batalova, Polina A. Voronina, Vladimir I. Shmurak, Richard O. Jenkins, Daria A. Belinskaia, Shmurak, V. I., Voronina, P.A., Belinskaia, D. A., Batalova, A.A., Jenkins, R. O., Goncharov, N. V., Mikhail A. Vovk, Vovk, M. A., Nikolay V. Goncharov   +13 more
core   +1 more source