Results 51 to 60 of about 13,218,886 (306)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Alterations in antioxidant function and cell apoptosis in duck spleen exposed to molybdenum and/or cadmium

Journal of Veterinary Sciences, 2017
To investigate the effects of molybdenum (Mo) and/or cadmium (Cd) on antioxidant function and the apoptosis-related genes in duck spleens. Sixty healthy 11-day-old ducks were randomly divided into six groups of 10 ducks (control, low Mo group, high Mo ...
Mengmeng Zhang, Junrong Luo, Caiying Zhang, H. Cao, B. Xia, G. Hu   +5 more
semanticscholar   +1 more source

Effects of Glutamine on Digestive Function and Redox Regulation in the Intestines of Broiler Chickens Challenged with Salmonella Enteritidis [PDF]

Brazilian Journal of Poultry Science, 2019
The aim was to investigate the effect of glutamine (Gln) on broilers challenged with Salmonella Enteritidis. 240 1-day-old birds were divided into four groups in a completely randomized design, each of which included 6 replicates with 10 birds per ...
Q Wu, Z Liu, S Li, C Jiao, Y Wang, Y Wang   +5 more
doaj   +1 more source

Antioxidant Function of Coenzyme Q

Journal of Nutritional Science and Vitaminology, 1992
Evidence for in vivo antioxidative activity of reduced CoQ homologs has been presented. This came from studies with experimental endotoxemia in mice, reoxygenation of rat liver following ischemia, and reoxygenation of canine heart following 24-hour cold preservation.
openaire   +3 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Oligodendrocytes Provide Antioxidant Defense Function for Neurons by Secreting Ferritin Heavy Chain

Cell Metabolism, 2020
Summary An evolutionarily conserved function of glia is to provide metabolic and structural support for neurons. To identify molecules generated by glia and with vital functions for neurons, we used Drosophila melanogaster as a screening tool, and ...
Chaitali Mukherjee, T. Kling, Belisa Russo, Kerstin Miebach, E. Keß, Martina Schifferer, Liliana D Pedro, Ulrich Weikert, M. K. Fard, N. Kannaiyan, M. Rossner, M. Aicher, S. Goebbels, K. Nave, Eva-Maria Krämer-Albers, A. Schneider, M. Simons   +16 more
semanticscholar   +1 more source

Effects of a powder made from three medicinal plants on growth performance, intestinal health, antioxidant activity, and anti-inflammatory ability in Xianghuang chickens

Frontiers in Veterinary Science
This study investigated the effect of a traditional Chinese medicine (TCM) plant powder made from an equal proportion of Sarcococca ruscifolia Stapf, Hedera nepalensis var.
Can Yang, XiaoWu Tang, RunTao Wu, YunMiao Jiang, Qi Quan, YuTian Xiao, JiaXuan Kuang, JiaYi Chen, QingHai Tang, Zhi Jiang   +9 more
doaj   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

FEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Tea Catechins: Potential Plant-Derived Feed Additives for Improving Chicken Intestinal Health and Productivity

Animals
In response to the global antimicrobial resistance and residue issues, most countries and regions have implemented comprehensive bans on the use of growth-promoting antibiotics in animal feed formulations.
Bing Tian, Wenjing Zhuang, Yanle Fan, Yun Hu, Xiaoyan Cui, Tingting Li, Liyang Zhang, Xugang Luo, Shengchen Wang   +8 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source