Results 51 to 60 of about 618,778 (269)

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Investigation of Phytochemical Compounds, antioxidant Potential and the Antimicrobial Effect of Bergamot Essential Oil on some Pathogenic Strains Causing Infection Invitro

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām, 2019
Introduction: Bergamot (Citrus bergamia) belongs to the Rutaceae family. The purpose of this study was to identify the phytochemical compounds and antioxidant activity of Bergamot essential oil as well as investigating the effect of its antimicrobial ...
Mohammad Noshad, Behrooz Alizadeh behbahani   +1 more
doaj  

Pharmacological profiling and phytochemical analysis of fractionated extracts of Euphorbia royleana

Notulae Botanicae Horti Agrobotanici Cluj-Napoca
Euphorbia royleana belongs to family Euphorbiaceae, with great therapeutic potential. The present study is aimed to validate its traditional uses. GC-MS analysis of Euphorbia royleana crude and fractionated extracts were performed.
Neelum NAHEED, Yamin BIBI, Sehrish IMRAN, Shamin AKHTAR, Abdullah A. ALARFAJ, Mohammad J. ANSARI, Abdul QAYYUM   +6 more
doaj   +1 more source

Evaluation of the antioxidant, anti-inflammatory, and anti-tumoral properties of bioactive compounds extracted from murta berries (Ugni molinae T.) dried by different methods

Frontiers in Plant Science, 2023
This study evaluated the effects of different drying methods (freeze drying, vacuum drying, infrared drying, convective drying, and sun drying) on the biological properties of berries from the Chilean murta (Ugni molinae Turcz) shrub.
Jéssica López, Antonio Vega-Gálvez, Kong S. Ah-Hen, Angela Rodríguez, Issis Quispe-Fuentes, Issis Quispe-Fuentes, Carla Delporte, Gabriela Valenzuela-Barra, Yennyfer Arancibia, Yennyfer Arancibia, Angara Zambrano, Angara Zambrano   +11 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Unseparated Olive Pruning Waste as a Sustainable Feedstock: DoE-Optimized Extracts with Antioxidant Activity Equivalent to Isolated Leaves

Antioxidants
Olive cultivation generates substantial pruning waste, yet current valorization strategies focus solely on leaves despite the logistical challenges of separating them.
Elisabetta Tumminelli, Valeria Cavalloro, Daniela Ratto, Giorgio Marrubini, Emanuela Martino, Paola Rossi, Daniela Rossi, Simona Collina   +7 more
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Iron oxide nanoparticles alleviate salt-alkaline stress and improve growth by modulating antioxidant defense system in cherry tomato

Journal of Plant Interactions
The integration of nanoparticles (NPs) into agriculture is altering traditional methods, enhancing productivity and sustainability. This study explores the application of iron oxide nanoparticles (FeONPs) to mitigate salt-alkaline stress in cherry ...
Raheel Shahzad, Putri Widyanti Harlina, Shahid Ullah Khan, Sri Koerniati, Bernadetta Rina Hastilestari, Ratih Asmana Ningrum, Rizwan Wahab, Ivica Djalovic, P. V. Vara Prasad   +8 more
doaj   +1 more source

Differentiating Two Species of ‘Mother-of-Thousands’: Kalanchoe daigremontiana and Kalanchoe x houghtonii [PDF]

Brazilian Archives of Biology and Technology
The widespread medicinal use of Kalanchoe daigremontiana and Kalanchoe × houghtonii, both popularly known as “mother-of-thousands”, often leads to their interchangeable use in folk medicine despite their distinct species status.
Evelyn Assis de Andrade, Isadora Machinski, Valter Paes de Almeida, Wilmer Hervet Perera, Robert Thomas Williamson, Wendy Karen Strangman, Jane Manfron, Flávio Luís Beltrame   +7 more
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source