Results 41 to 50 of about 842,941 (248)

Assay of the antioxidant capacity of foods using an iron(II)-catalysed lipid peroxidation model for greater nutritional relevance [PDF]

, 2010
The formation of free radicals by the iron-catalysed Fenton reaction is a major cause of oxidative damage in the body. Here a common assay of antioxidant capacity, inhibition of the β-carotene-linoleic acid model of lipid peroxidation, has been modified ...
Molan, Peter C., Peter C. Molan, Hélène L. Brangoulo, Brangoulo, Helene L.   +3 more
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Modulation of T-Cell-Dependent Humoral Immune Response to Influenza Vaccine by Multiple Antioxidant/Immunomodulatory Micronutrient Supplementation

Vaccines
Notwithstanding prevalence gaps in micronutrients supporting immune functions, the significance of their deficits/supplementation for the efficacy of vaccines is underinvestigated.
Biljana Bufan, Nevena Arsenović-Ranin, Irena Živković, Ivana Ćuruvija, Veljko Blagojević, Luka Dragačević, Ana Kovačević, Jelena Kotur-Stevuljević, Gordana Leposavić   +8 more
doaj   +1 more source

The ‘vitamin E regeneration system’ (VERS) and an algorithm to justify antioxidant supplementation in diabetes – A hypothesis

, 2008
In studies of vitamin E effectiveness in diabetes, there are still controversies surrounding negative observational and positive experimental results.
Jelinek, Herbert F., Nwose, Ezekiel U., Kerr, Philip G., Richards, Ross S.   +3 more
core   +1 more source

Eggshell appearance does not signal maternal corticosterone exposure in Japanese quail: an experimental study with brown-spotted eggs [PDF]

, 2013
Reproduction is a critical period for birds as they have to cope with many stressful events. One consequence of an acute exposure to stress is the release of corticosterone, the avian stress hormone.
Ivan Mikšík (492331), Spencer, Karen A., Duval Camille, Miksik, Ivan, Mikšík Ivan, Paul G Lovell, Duval, C., Lovell, P., Karen A Spencer, Paul G. Lovell (492330), Reynolds, S., Spencer Karen A., Reynolds S. James, Karen A. Spencer (492333), Phillip Cassey, Camille Duval (360534), Spencer, K., Phillip Cassey (244230), S. James Reynolds (492332), Camille Duval, Miksik, I., S James Reynolds, Lovell Paul G., Cassey, Phillip, Reynolds, S. James, Cassey, P., Duval, Camille, Lovell, Paul G., Ivan Mikšík, Lovell, P. George; id_orcid, Cassey Phillip, Spencer, Karen A.; id_orcid   +31 more
core   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Effect of Dietary Vitamin E on Growth Performance, Immunity and Antioxidant Capacity in Male Jiangnan White Goslings from 1 to 28 d of Age

Agriculture, 2022
This experiment aimed to investigate effects of the different dietary levels of vitamin E (VE) on the growth performance, immunity and antioxidant capacity of goslings.
Qingyu Sun, Haiming Yang, Jun Yu, Jingru Liang, Xuean Xu, Zhiyue Wang   +5 more
doaj   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source