Results 221 to 230 of about 23,437,147 (340)

Diurnal Operation of the Xanthophyll Cycle and the Antioxidant System in Apple Peel [PDF]

, 2004
Lailiang Cheng, Fengwang Ma
openalex   +1 more source

DNA‐PKcs‐Driven YAP1 Phosphorylation and Nuclear Translocation: a Key Regulator of Ferroptosis in Hyperglycemia‐Induced Cardiac Dysfunction in Type 1 Diabetes

Advanced Science, EarlyView.
In the context of chronic hyperglycemia, a DDR is initiated, leading to the pathological activation of DNA‐PKcs in the diabetic heart. This activated DNA‐PKcs directly interacts with and phosphorylates YAP1 at Thr226, thereby increasing the nuclear expression of YAP1.
Junyan Wang, Xing Chang, Chun Li, Jing Gao, Zhijiang Guo, Haowen Zhuang, Lingjun Wang, Yusheng Huang, Wei Wang, Chao Li, Qingyong He   +10 more
wiley   +1 more source

Melatonin Promotes Yield Increase in Wheat by Regulating Its Antioxidant System and Growth Under Drought Stress. [PDF]

Biology (Basel)
Li X, Liu J, Zhang C, Liu Z, Guo X, Li S, Li H, Liu K, Li K, Ding M.   +9 more
europepmc   +1 more source

Reactive oxygen species, antioxidant systems and nitric oxide in peroxisomes

, 2002
Luis A. del Rı́o
openalex   +1 more source

An Antioxidant System Required for Host Protection against Gut Infection in Drosophila [PDF]

, 2005
Eun-Mi Ha, Chun-Taek Oh, Ji-Hwan Ryu, Yun-Soo Bae, Sang-Won Kang, In-hwan Jang, Paul T. Brey, Won‐Jae Lee   +7 more
openalex   +1 more source

Neuraminidase 1 Exacerbated Glycolytic Dysregulation and Cardiotoxicity by Destabilizing SIRT1 through Interactions with NRF2 and HIF1α

Advanced Science, EarlyView.
NEU1, a key regulator of glycolysis, is markedly upregulated following DOX treatment. This upregulation is attributed to HIF1α’s transcriptional repression, requiring intricate interactions with NRF2. Increased NEU1 facilitates SIRT1 lysosomal degradation, contributing to aberrant glycolytic phenotype and cardiac damage.
Ting Gao, Yufeng Tang, Tao Zeng, Jie Wang, Xiaohui Zhang, Qingbo Liu, Xun Guan, Xinyu Tang, Guangping Lu, Jiahao Li, Mingrui Liu, Dongmei Zhang, Sixuan Lv, Junlian Gu   +13 more
wiley   +1 more source

METTL3, an Independent Adverse Prognostic Factor for AML, Promotes the Development of AML by Modulating the PGC-1α-MAPK Pathway and PGC-1α-Antioxidant System Axis. [PDF]

Cancer Med
Tang Y, Liu X, Ye W, Wang X, Wei X, Du Y, Zhang Y, Gong Y.   +7 more
europepmc   +1 more source

Antioxidant Defense System Induced by a Methanol Extract ofCaesalpinia bonducella. in Rat Liver [PDF]

, 2005
M Gupta, U. K. Mazumder, Rajesh Kumar, T. Sivakumar, P. Gomathi, Rajeshwar Yerra   +5 more
openalex   +1 more source

Isoquercitrin Alleviates Diabetic Nephropathy by Inhibiting STAT3 Phosphorylation and Dimerization

Advanced Science, EarlyView.
This study identified a natural compound, isoquercitrin, which significantly alleviated kidney inflammation and fibrosis by inhibiting STAT3 activity. Isoquercitrin forms a strong, noncovalent bond that directly binds to STAT3. Isoquercitrin binds to the pY+1 pocket of the SH2 domain of STAT3 via hydrogen bonding with Ser668, Gln635, and Gln633 ...
Chen Xuan, Donghui Chen, Shuangna Zhang, Chaofan Li, Qingyun Fang, Dinghua Chen, Jiabao Liu, Xin Jiang, Yingjie Zhang, Wanjun Shen, Guangyan Cai, Xiangmei Chen, Ping Li   +12 more
wiley   +1 more source

Root-Knot Nematode Early Infection Suppresses Immune Response and Elicits the Antioxidant System in Tomato. [PDF]

Int J Mol Sci
Molinari S, Farano AC, Leonetti P.
europepmc   +1 more source