Results 271 to 280 of about 23,628,110 (297)

Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors

Advanced Science, EarlyView.
Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen, Riya Gupta, Yosuke M. Morizawa, Yu Qin, Xingyu Du, Cynthia Pang, Osama Al‐Dalahmah, Maura B. Dupont, Guang Yang   +8 more
wiley   +1 more source

Effect of exogenous melatonin on growth and antioxidant system of pumpkin seedlings under waterlogging stress. [PDF]

PeerJ
Liu Z, Sun L, Liu Z, Li X.
europepmc   +1 more source

ACSL5 Regulates Glucose Metabolism and Chemotherapy Sensitivity in Colorectal Cancer Cells under Glutamine Deficiency

Advanced Science, EarlyView.
Glutamine deprivation triggers ACSL5 upregulation in tumor cells, sustaining their viability via dual metabolic rewiring programs. ACSL5 enhances glycolysis by relieving p53's inhibition of PGAM1 while also sustaining mitochondrial respiration and TCA cycle flux through promoting IDH2 dimerization.
Shuai Tian, Qiaoxia Zhang, Xuedan Sun, Rick Francis Thorne, Zeyuan Shi, Qiang Ji, Zhangran Sun, Yuanxiang Lu, Qun Zhao, Xianjun Yu, Wanglai Hu, Mian Wu   +11 more
wiley   +1 more source

<i>Trichoderma asperellum</i> 22043: Inoculation Promotes Salt Tolerance of Tomato Seedlings Through Activating the Antioxidant System and Regulating Stress-Resistant Genes. [PDF]

J Fungi (Basel)
Hu G, Zhao Z, Wei Y, Hu J, Zhou Y, Li J, Yang H.   +6 more
europepmc   +1 more source

Single‐Position Peptide Clustering for Peptidomics Reveals Novel Disease Biomarkers and Dysregulated Proteolytic Characteristics

Advanced Science, EarlyView.
A novel amino acid (aa)‐score‐based single‐position peptide clustering strategy is developed for peptidomics, enabling precise profiling of protein proteolysis in plasma from β‐thalassemia cohort. The method identifies new aa position‐based peptide cluster biomarkers validated by heavy‐labeled peptides, visualizes aggregated changes, uncovers disease ...
Na Li, Yaxin Zhu, Yumeng Yan, Jifeng Wang, Lili Niu, Xiang Ding, Mengmeng Zhang, Zhensheng Xie, Tanxi Cai, Xiaojing Guo, Jianming Luo, Peng An, Xiangqian Guo, Fuquan Yang   +13 more
wiley   +1 more source

Effects of Nitrogen Deficiency on the Photosynthesis, Chlorophyll a Fluorescence, Antioxidant System, and Sulfur Compounds in Oryza sativa. [PDF]

Int J Mol Sci
Chen LH, Xu M, Cheng Z, Yang LT.
europepmc   +1 more source

Salinity Stress Resilience in Sorghum bicolor through Pseudomonas-Mediated Modulation of Growth, Antioxidant System, and Eco-Physiological Adaptations. [PDF]

ACS Omega
Azeem M, Sultana R, Ahmed N, Abbasi MW, Hasan KA, Dong R, Alamri S, Alfagham AT.   +7 more
europepmc   +1 more source

Toxicity of Moxifloxacin on the Growth, Photosynthesis, Antioxidant System, and Metabolism of Microcystis aeruginosa at Different Phosphorus Levels. [PDF]

Toxics
Wan L, Zhou Y, Huang R, Jiao Y, Gao J.
europepmc   +1 more source

Foliar application of sodium selenite affects the growth, antioxidant system, and fruit quality of strawberry. [PDF]

Front Plant Sci
Lin Y, Cao S, Wang X, Liu Y, Sun Z, Zhang Y, Li M, Wang Y, He W, Zhang Y, Chen Q, Wang X, Luo Y, Tang H.   +13 more
europepmc   +1 more source