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The thioredoxin antioxidant system.
Free Radical Biology and Medicine, 2014The thioredoxin (Trx) system, which is composed of NADPH, thioredoxin reductase (TrxR), and thioredoxin, is a key antioxidant system in defense against oxidative stress through its disulfide reductase activity regulating protein dithiol/disulfide balance.
Jun Lu, A. Holmgren
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Systems biology of antioxidants
Clinical Science, 2012Understanding the role of oxidative injury will allow for therapy with agents that scavenge ROS (reactive oxygen species) and antioxidants in the management of several diseases related to free radical damage. The majority of free radicals are generated by mitochondria as a consequence of the mitochondrial cycle, whereas free radical accumulation is ...
Andriantsitohaina, Ramaroson+10 more
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Antioxidant systems in insects
Archives of Insect Biochemistry and Physiology, 1995AbstractInsects possess a suite of antioxidant enzymes and small molecular weight antioxidants that may form a concatenated response to an onslaught of dietary and endogenously produced oxidants. Antioxidant enzymes such as superoxide dismutase, catalase, glutathione transferase, and glutathione reductase have been characterized in insects.
Clinton B. Summers, Gary W. Felton
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Antioxidative system of Deinococcus radiodurans
Research in Microbiology, 2020Deinococcus radiodurans is famous for its extreme resistance to various stresses such as ionizing radiation (IR), desiccation and oxidative stress. The underlying mechanism of exceptional resistance of this robust bacterium still remained unclear. However, the antioxidative system of D.
Fangzhu Xiao+5 more
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Redox Systems, Antioxidants and Sarcopenia
Current Protein & Peptide Science, 2018According to the free-radical theory of aging, oxidative stress is a key contributor to the onset of age-related conditions by inducing structural and functional alterations in several cellular components. Although innate defenses exist for limiting the occurrence of such detrimental effects, their ability to counteract the continuous and large ...
Fougère, Bertrand+126 more
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, 2020
In recent years, supplementing herbal medicines to fish diets in the aquaculture industry as a growth stimulant and immunostimulant is a common practice.
Reza Zeilab Sendijani+3 more
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In recent years, supplementing herbal medicines to fish diets in the aquaculture industry as a growth stimulant and immunostimulant is a common practice.
Reza Zeilab Sendijani+3 more
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Delivery systems for antioxidant nutrients
Toxicology, 2002The novel role of oxidants and antioxidants as part of cell signaling cascades has opened new areas of research in several disease states and their therapeutic strategies. For successful therapeutic manipulation of reactive oxygen species (ROS)-mediated cellular signaling pathways, it would necessitate control of the critical balance of oxidants ...
Jiro Takata+2 more
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Antioxidant system and ozone tolerance
Environmental Research, 1983Rats were initially exposed to 2 ppm ozone for 3 hr in order to induce ozone tolerance. The time course of the content of nonprotein SH as well as the activities of glutathione peroxidase, glutathione reductase, and glucose 6-phosphate dehydrogenase (so-called antioxidant system) in lungs of the animals was compared to the development of tolerance in ...
Ziro Nambu, Eiji Yokoyama
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Enzymatic antioxidant system of endotheliocytes
Doklady Biochemistry and Biophysics, 2016It is shown that endothelial cells from human umbilical vein have a reduced activity and gene expression of the "classic" antioxidant enzymes (Cu,Zn-superoxide dismutase, catalase, and Se-containing glutathione peroxidase). At the same time, a high expression level of peroxiredoxin genes was identified in the same endothelial cells, which obviously ...
Mars G. Sharapov+6 more
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