Results 71 to 80 of about 23,437,147 (340)

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Removal of nutrients from water column and physiological responses of Vallisneria natans under sulfonamide stress

Journal of Freshwater Ecology, 2019
For a better understanding of the metabolic adaptations to sulfonamide (SA) stress in submerged macrophytes, the alterations of nutrient element uptake and secondary metabolism were studied in the leaves of Vallisneria natans (Lour.) Hara exposed to 0 ...
Houtao Xu, Liming Zhu, Liqing Wang, Xiaoyan Zheng, Linkui Cao   +4 more
doaj   +1 more source

Combined Effects of Sulfamethoxazole and Erythromycin on a Freshwater Microalga, Raphidocelis subcapitata: Toxicity and Oxidative Stress

Antibiotics, 2021
This study investigated the environmental effects of two familiar emerging contaminants, sulfamethoxazole (SMX) and erythromycin (ERY), and their mixture (10:1 w/w) using a green microalga, R. subcapitata.
Yibo Zhang, Da He, Fang Chang, Chenyuan Dang, Jie Fu   +4 more
doaj   +1 more source

Caffeine Modulates the Dynamics of DODAB Membranes: Role of the Physical State of the Bilayer [PDF]

, 2020
Caffeine (1,3,7-trimethylxanthine), an ingredient of coffee, is used worldwide as a psychostimulant, antioxidant, and adjuvant analgesic. To gain insights into the action mechanism of caffeine, we report on its effects on the phase behaviour and microscopic dynamics of a dioctadecyldimethylammonium bromide (DODAB) lipid membrane, as studied ...
arxiv   +1 more source

Boundaries of photosynthesis: adaptations of carbon fixation in extreme environments

FEBS Open Bio, EarlyView.
Photosynthesis faces challenges from environmental extremes of temperature, pH, and salinity, limiting gas diffusion, modifying membrane fluidity, and destabilizing photochemical and biochemical reactions. Photosynthetic organisms have evolved unique adaptations overcoming these stresses and maintaining their photosynthetic activity.
Pere Aguiló‐Nicolau, Concepción Iñiguez, Sebastià Capó‐Bauçà, Jeroni Galmés   +3 more
wiley   +1 more source

Role of Glutathione-Ascorbate Cycle and Photosynthetic Electronic Transfer in Alternative Oxidase-Manipulated Waterlogging Tolerance in Watermelon Seedlings

Horticulturae, 2021
Alternative oxidase (AOX) has been documented to mitigate the oxidative stress caused by abiotic stresses. However, it remains unknown how AOX regulates the antioxidant system and photosynthesis under waterlogging.
Jiawen Zheng, Chunying Fang, Lei Ru, Nan Sun, Yuanyuan Liu, Yunping Huang, Yuhong Wang, Zhujun Zhu, Yong He   +8 more
doaj   +1 more source

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

FEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna, Richard Buchal, Martin Leníček, Amit Shachak, Jan Pláteník   +4 more
wiley   +1 more source

Drug management of oxidation-reduction state of the body in respiratory tract diseases (part 2)

Zdorovʹe Rebenka, 2018
The review of the literature presents modern data on the activators of the transcription factor NFE2L2 and mimetics of antioxidant enzymes. Their effect on the oxidation-reduction state in diseases of the respiratory system is shown.
A.E. Abaturov, A.P. Volosovets, T.P. Borysova   +2 more
doaj   +1 more source

Chitosan Coating to Preserve the Qualitative Traits and Improve Antioxidant System in Fresh Figs (Ficus carica L.)

Agriculture, 2019
Chitosan-based coatings are used as a postharvest treatment to extend the shelf-life of several fruits. In this study, the effectiveness of chitosan-based coating to preserve the physico-chemical (weight loss, soluble solid content, and titratable ...
G. Adiletta, L. Zampella, Caterina Coletta, M. Petriccione   +3 more
semanticscholar   +1 more source

CNS Mitochondria‐Derived Vesicle in Blood: Potential Biomarkers for Brain Mitochondria Dysfunction

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial dysfunction is a hallmark of neurodegenerative diseases like Alzheimer's (AD) and Parkinson's (PD). Our goal was to develop practical, noninvasive methods to assess mitochondrial status through the detection of mitochondria‐derived vesicles (MDVs).
Qi Liu, Wentao Chen, Yahong Wu, Zhen Guo, Jun Chen, Chen Tian, Pan Wang, Shaopeng Zeng, Bin Xu, Jing Duan, Shilong Han, Xiao Xiong, Jing Zhang   +12 more
wiley   +1 more source