Results 341 to 350 of about 1,350,805 (429)

Growth of Spirulina spp. at different temperatures and their impact on pigment production, oxidants and antioxidants profile. [PDF]

open access: yesPLoS One
Rehman M   +10 more
europepmc   +1 more source

ISG15 Enhances the Activity of γ‐Glutamate Cysteine Ligase to Suppress Apoptosis in High Fat Diet‐Promoted Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
Hepatocellular carcinoma (HCC) cells under high‐fat environment constrain harmful reactive oxygen species (ROS) by enhancing glutathione synthesis though upregulating interferon stimulated gene 15 (ISG15). In this process, upregulated high mobility group A1 (HMGA1) enhances ISG15 transcription, upregulated ISG15 subsequently noncovalently binds with ...
Xinran Liu   +21 more
wiley   +1 more source

Single Test‐Based Diagnosis and Subtyping of Pulmonary Hypertension Caused by Fibrosing Mediastinitis Using Plasma Metabolic Analysis

open access: yesAdvanced Science, EarlyView.
Pulmonary hypertension caused by fibrosing mediastinitis has a five‐year survival rate of just 56%. Current diagnostic approaches are complex for patients with mobility limitations and can lead to misdiagnoses due to their nonspecific clinical features.
Yating Zhao   +17 more
wiley   +1 more source

Inhibition of Ferroptosis Delays Aging and Extends Healthspan Across Multiple Species

open access: yesAdvanced Science, EarlyView.
This study identifies ferroptosis as a key driver of cellular senescence, with its inhibition delaying aging and extending healthspan across species. During senescence, ferroptosis worsens, increasing oxidative stress and lipid peroxidation, which accelerate aging.
Hai‐Jun Fu   +15 more
wiley   +1 more source

Use of Natural Biomolecules in Animal Feed to Enhance Livestock Reproduction. [PDF]

open access: yesInt J Mol Sci
BenSouf I   +10 more
europepmc   +1 more source

Targeted STING Activation Using Modified Ultrasound‐Responsive Microbubbles Enhances Immune Checkpoint Blockade Against Melanoma

open access: yesAdvanced Science, EarlyView.
This study explores the use of ultrasound contrast agents loaded with Stimulator of Interferon Genes (STING) agonists as an approach to activate the body's immune system against cancer. Termed Microbubble‐assisted UltraSound‐guided Immunotherapy of Cancer (MUSIC), this strategy effectively inhibits tumor growth and improves survival in mouse models of ...
Sina Khorsandi   +12 more
wiley   +1 more source

Highly Oriented SiC@SiO2 Ceramic Fiber Aerogels with Good Anisotropy of the Thermal Conductivity and High‐Temperature Resistance

open access: yesAdvanced Science, EarlyView.
The anisotropic‐structure SiC@SiO2 ceramic fiber aerogels feature aligned layers stacking layer‐by‐layer with the same direction and highly oriented 1D fibers inside each layer, resulting in an anisotropy factor as high as 5.08. Not only does it have 60% high recoverable deformation, but it also shows great promise for thermal protection in extreme ...
Zheng Zhang   +7 more
wiley   +1 more source

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