Results 191 to 200 of about 118,600 (312)

Carbon dots as a smart nanoplatform for the blood‐brain barrier penetration and ischemic stroke therapy

open access: yesResponsive Materials, EarlyView.
This review presents the structure and transport routes of the blood‐brain barrier, summarizes the ischemic stroke pathophysiological cascade, and discusses the BBB‐crossing mechanisms and multitarget therapeutic effects of carbon dots, demonstrating their promising theranostic potential for ischemic stroke.
Yanhan Huang   +6 more
wiley   +1 more source

Halting the Progression of Acute Kidney Injury: A Tubular‐Inspired Reusable Detoxifier Against Protein‐Bound Uremic Toxins and Oxidative Stress

open access: yesSusMat, EarlyView.
This graphical ToC illustrates a tubular‐inspired detoxifier (SDCMs–DS) that halts acute kidney injury progression. Inspired by proximal tubular epithelial cells (PTECs), the biomimetic design combines dissociation‐adsorption clearance of protein‐bound uremic toxins (PBUTs) with antioxidant protection. During hemoperfusion, danshensu (DS) released from
Yilin Wang   +12 more
wiley   +1 more source

Oxidative and nitrosative damage in multiple sclerosis. [PDF]

open access: yesCurr Opin Neurol
Prozorovski T   +3 more
europepmc   +1 more source

Multiscale Effects of Environmentally Relevant Mixtures Containing Two Estrogenic Endocrine Disruptors, Chlordecone and Propylparaben, in Hydra vulgaris Pallas, 1766

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT This study investigates the chronic effects of chlordecone (CLD) and propylparaben (PP), two pro‐estrogenic endocrine disruptors, on Hydra vulgaris Pallas, 1766 using a multiscale approach over a 14‐day exposure period. Environmentally relevant concentrations of CLD (0.5, 5, 20 μg L−1) and PP (0.01, 0.05, 0.40 μg L−1) were tested individually ...
Magali Domallain   +8 more
wiley   +1 more source

Correction: Nobiletin reduces 5-FU-induced lung injury with antioxidative, anti-inflammatory and anti-apoptotic activities. [PDF]

open access: yesNaunyn Schmiedebergs Arch Pharmacol
Atila Uslu G   +5 more
europepmc   +1 more source

Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity

open access: yesVIEW, EarlyView.
Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin   +3 more
wiley   +1 more source

Harboring potential of enzymatic antioxidants in sweet potato [<i>Ipomoea batatas</i> (L.) Lam.] nodal cultures under <i>in vitro</i> NaCl-mediated salinity stress conditions. [PDF]

open access: yesFront Plant Sci
Mishra A   +9 more
europepmc   +1 more source

Plant‐derived nanovesicles as potential drug delivery systems for topical use: Emerging applications in dermatology and cosmetology

open access: yesVIEW, EarlyView.
Plant‐derived nanovesicles (PDNVs) are naturally secreted by fruit, vegetables, seeds, leaves and other natural sources. Used as drug delivery systems, they can combine intrinsic therapeutic activity, enhanced skin permeation and cargo‐carrying capacity, suitable for dermatological and cosmetic applications including hydration, antioxidant/anti ...
Dorotea Fiore   +5 more
wiley   +1 more source

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