Results 271 to 280 of about 948,009 (300)
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Toxicity, Antioxidants, and Metabolism
1989We all realize that oxygen is a dangerous friend. Oxygen is something that we cannot live without, but it is also a substance that we cannot live with indefinitely. This chapter will review two aspects of this subject. First, an overview will be given of some of the points relevant to the idea that oxygen is toxic by pointing out the underlying ...
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Effects of antioxidants on metabolism of aromatic polycyclic hydrocarbons
Advances in Enzyme Regulation, 1976Abstract A number of antioxidants have been shown to inhibit the neoplastic effects of a variety of chemical carcinogens. Some of these antioxidants such as BHA and BHT are widely distributed in the environment, and it is possible that they could play a role in diminishing the impact of exposures to chemical carcinogens.
L W, Wattenberg, J, Speier, A, Kotake
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Ageing, Metabolic Dysfunction, and the Therapeutic Role of Antioxidants
2023The gradual ageing of the world population has been accompanied by a dramatic increase in the prevalence of obesity and metabolic diseases, especially type 2 diabetes. The adipose tissue dysfunction associated with ageing and obesity shares many common physiological features, including increased oxidative stress and inflammation.
Ana L, Santos, Sanchari, Sinha
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Interaction of Anthocyanins with Drug-metabolizing and Antioxidant Enzymes
Current Medicinal Chemistry, 2013Anthocyanins are generally considered to be the largest and the most important group of water-soluble pigments in plants. They are widely consumed by humans as natural compounds of vegetables, fruits, and red wine. Anthocyanins as well as other flavonoids show protective qualities against variety of pathologies, including cardiovascular diseases ...
H, Bártíková +3 more
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Effect of aging on glutathione metabolism. Protection by antioxidants
1992The free radical theory of aging suggests that oxygen free radicals may be involved in the aging process. Thus, changes in antioxidant mechanisms may occur with aging. Since glutathione is one of the most effective antioxidant systems in the cell, its metabolism may change with aging.
J, Viña +5 more
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Neuroprotection by the Metabolic Antioxidant α-Lipoic Acid
Free Radical Biology and Medicine, 1997Reactive oxygen species are thought to be involved in a number of types of acute and chronic pathologic conditions in the brain and neural tissue. The metabolic antioxidant alpha-lipoate (thioctic acid, 1, 2-dithiolane-3-pentanoic acid; 1, 2-dithiolane-3 valeric acid; and 6, 8-dithiooctanoic acid) is a low molecular weight substance that is absorbed ...
L, Packer, H J, Tritschler, K, Wessel
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Intake and circulating concentrations of antioxidants in metabolic syndrome
Current Atherosclerosis Reports, 2006Metabolic syndrome, which occurs commonly in populations around the world, has been associated with an increased risk for developing cardiovascular disease and diabetes. Oxidative stress, which has been implicated in the pathogenesis of cardiovascular disease and diabetes, is a common feature of metabolic syndrome.
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[Metabolism and antioxidant function of glutathione].
Pathologie-biologie, 1996Glutathione (gamma-glutamyl-cysteinyl-glycine or GSH) is a cysteine-containing tripeptide with reducing and nucleophilic properties which play an important role in cellular protection from oxidative damage of lipids, proteins and nucleic acids. GSH regulates the metabolism of proteins and their activities by means of thiol-disulfide exchange.
D, Gérard-Monnier, J, Chaudiere
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The Role of Metabolism in the Antioxidant Function of Vitamin E
Critical Reviews in Toxicology, 1993Vitamin E (alpha-tocopherol), the principal chain-breaking antioxidant in biological membranes, prevents toxicant- and carcinogen-induced oxidative damage by trapping reactive oxyradicals. Although alpha-tocopherol antioxidant reactions appear to be not under direct metabolic control, alpha-tocopherol may function through redox cycles, which deliver ...
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