Results 21 to 30 of about 3,678,963 (228)
European Journal of Medicinal Chemistry, 2013 As part of our efforts aimed at searching for new antiparasitic agents, 2-alkylmercaptoethyl-1,1-bisphosphonate derivatives were synthesized and evaluated against Trypanosoma cruzi, the etiologic agent of Chagas disease, and Toxoplasma gondii, the ...
Marion Recher +8 more
semanticscholar +3 more sources
Synthesis and Evaluation of (Bis)benzyltetrahydroisoquinoline Alkaloids as Antiparasitic Agents [PDF]
JACS AuAna Sozanschi +6 more
doaj +2 more sources
Traditional Latvian herbal medicinal plants used to treat parasite infections of small ruminants: A review [PDF]
Veterinary World, 2021 Numerous treatment agents offering prophylaxis against livestock parasites are commercially available. However, because of increasing antiparasitic drug resistance, the increased popularity of environmentally friendly lifestyle choices, and organic ...
Alīna Kļaviņa +4 more
doaj +1 more source
Antiparasitic Agent Atovaquone [PDF]
Antimicrobial Agents and Chemotherapy, 2002 Atovaquone is a unique naphthoquinone with broad-spectrum antiprotozoal activity. It is effective for the treatment and prevention of Pneumocystis carinii pneumonia (PCP), it is effective in combination with proguanil for the treatment and prevention of malaria, and it is effective in combination with azithromycin for the treatment of babesiosis. There
Aaron L, Baggish, David R, Hill
openaire +3 more sources
Bioorganic chemistry (Print), 2023 Design of tubulin inhibitors as anticancer drugs dynamically developed over the past 20 years. The modern arsenal of potential tubulin-targeting anticancer agents is represented by small molecules, monoclonal antibodies, and antibody-drug conjugates ...
Magdalena Podolak +8 more
semanticscholar +1 more source
Overview of Biologically Active Nucleoside Phosphonates
Frontiers in Chemistry, 2021 The use of the phosphonate motif featuring a carbon-phosphorous bond as bioisosteric replacement of the labile P–O bond is widely recognized as an attractive structural concept in different areas of medicinal chemistry, since it addresses the very ...
Elisabetta Groaz, Steven De Jonghe
doaj +1 more source
From Magic Bullet to Magic Bomb: Reductive Bioactivation of Antiparasitic Agents.
ACS Infectious Diseases, 2021 Paul Ehrlich coined the term "magic bullet" to describe how a drug kills the parasite inside its human host without harming the host itself. Ehrlich concluded that the drug must have a greater affinity to the parasite than to human cells.
S. Wittlin, P. Mäser
semanticscholar +1 more source
FACTORS LIMITING THE EFFECTIVENESS OF INTESTINAL PARASITOSES’ PHARMACOTHERAPY [PDF]
Journal of IMAB, 2017 The effective etiological antiparasitic treatment fulfils two major goals - to cure the infected patient and to terminate its role as an epidemiologically relevant source of infection.
Kalina Stoyanova +3 more
doaj +1 more source
2-Amino-1,3,4-thiadiazoles as prospective agents in trypanosomiasis and other parasitoses
Acta Pharmaceutica, 2020 Parasitic diseases are a serious public health problem affecting hundreds of millions of people worldwide. African trypanosomiasis, American trypanosomiasis, leishmaniasis, malaria and toxoplasmosis are the main parasitic infections caused by protozoan ...
Serban Georgeta
doaj +1 more source
Anthelmintic resistance in Creole horses in the South of Rio Grande do Sul, Brazil
Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2021 The objective of the study was to evaluate the antiparasitic resistance against horse nematodes in the South of Rio Grande do Sul, Brazil. The results concerning the tests of anthelmintic efficacy on horses, stored in the database of the Parasitic ...
J.S. Lignon +9 more
doaj +1 more source