Results 41 to 50 of about 3,203,567 (223)

Genome‐Wide Association Studies of Polysaccharides, Collagen, and Saponin Traits in the Sea Cucumber Apostichopus japonicus

open access: yesAquaculture Research, Volume 2025, Issue 1, 2025.
Apostichopus japonicus is a commercially important marine species known for its high nutritional value and a range of bioactive compounds, including polysaccharides, collagen, and saponins. In this study, a genome‐wide association study (GWAS) was carried out on 143 A. japonicus individuals.
Yongjie Wang   +15 more
wiley   +1 more source

Synthesis of Various Dihydro–Thiazole and Selenazole Heterocycles

open access: yesEuropean Journal of Organic Chemistry, Volume 27, Issue 43, November 18, 2024.
The synthesis of thiazole derivatives was achieved by reacting I2/SCN− with various push‐pull alkenes. The substitution followed by intramolecular cyclization under mild conditions resulted in the desired products. When KSeCN was used, a selenazole derivative was formed.
Mihály Viktor Pilipecz   +7 more
wiley   +1 more source

Hypothesizing repetitive paraphilia behavior of a medication refractive Tourette's syndrome patient having rapid clinical attenuation with KB220Z-nutrigenomic amino-acid therapy (NAAT) [PDF]

open access: yes, 2013
Background and aims: Many patients presenting multiple behaviors including drug and food abuse as well as other pathological repetitive unwanted activities such as gambling, self-mutilation and paraphilias may not be appropriately diagnosed.
Barh, Debmayla   +13 more
core   +1 more source

Association between Parkinson’s disease and cardiovascular disease mortality: a prospective population-based study from NHANES

open access: yesLipids in Health and Disease
Background and aim Conflicting results have been reported on the association between Parkinson's disease (PD) and cardiovascular disease (CVD) mortality in different populations.
Li Ke   +3 more
doaj   +1 more source

Patients' perspective on their drug therapy after bariatric surgery: A quantitative, cross‐sectional interview study

open access: yesClinical Obesity, Volume 14, Issue 5, October 2024.
Graphical abstract on the background, methods, summarized results and conclusion of the study. Summary Drug therapy in patients who have undergone bariatric surgery is challenging. We aimed to investigate the patients' perspective on their drug therapy.
Susanne Schiek   +9 more
wiley   +1 more source

Somatostatin and dopamine receptors as targets for medical treatment of Cushing's Syndrome [PDF]

open access: yes, 2008
Somatostatin (SS) and dopamine (DA) receptors are widely expressed in neuroendocrine tumours that cause Cushing's Syndrome (CS). Increasing knowledge of specific subtype expression within these tumours and the ability to target these receptor subtypes ...
A Colao   +115 more
core   +3 more sources

Interactions of the antiviral and antiparkinson agent amantadine with lipid membranes and human erythrocytes

open access: yesBiophysical Chemistry, 2015
Aimed to better understand the molecular mechanisms of its interactions with cell membranes, human erythrocyte and molecular models of the red cell membrane were utilized. The latter consisted of bilayers of dimyristoylphosphatidylcholine (DMPC) and dimyristoylphosphatidylethanolamine (DMPE), representative of phospholipid classes located in the outer ...
Suwalsky, Mario   +5 more
openaire   +5 more sources

Prevalence of Late‐Stage Parkinson's Disease in the US Healthcare System: Insights from TriNetX

open access: yesMovement Disorders, Volume 39, Issue 9, Page 1592-1601, September 2024.
Abstract Background Patients in late‐stage Parkinson's disease (PDLS) are caregiver‐dependent, have low quality of life, and higher healthcare costs. Objective To estimate the prevalence of PDLS patients in the current US healthcare system. Methods We downloaded the 2010–2022 data from the TriNetX Diamond claims network that consists of 92 US ...
Sol De Jesus   +9 more
wiley   +1 more source

Pramipexole protective effect on rotenone induced neurotoxicity in mice [PDF]

open access: yes, 2011
Introduction: Pramipexole is a new dopaminergic drug which has been approved for PD treatment. However, we tried to find a new capacity for this drug rather than symptomatic effect. Materials and Methods: A chronic
Abdelaziz A. Ghanem   +6 more
core   +1 more source

Heterogeneous treatment effects of sodium‐glucose cotransporter 2 inhibitors on risk of dementia in people with type 2 diabetes: A population‐based cohort study

open access: yesAlzheimer's &Dementia, Volume 20, Issue 8, Page 5528-5539, August 2024.
Abstract INTRODUCTION Sodium‐glucose cotransporter 2 (SGLT2) inhibitors exhibit potential benefits in reducing dementia risk, yet the optimal beneficiary subgroups remain uncertain. METHODS Individuals with type 2 diabetes (T2D) initiating either SGLT2 inhibitor or sulfonylurea were identified from OneFlorida+ Clinical Research Network (2016–2022).
Huilin Tang   +12 more
wiley   +1 more source

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