Results 191 to 200 of about 249,854 (357)

Staging concept for aging management: Definition, mechanism, and coping strategies

open access: yesVIEW, EarlyView.
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang   +6 more
wiley   +1 more source

Guided de-escalation of antiplatelet treatment in patients with acute coronary syndrome undergoing percutaneous coronary intervention (TROPICAL-ACS): a randomised, open-label, multicentre trial.

open access: yesThe Lancet, 2017
D. Sibbing   +23 more
semanticscholar   +1 more source

Biomarkers to predict outcomes in diabetic foot ulcers

open access: yesVIEW, EarlyView.
Studies attempting to predict the healing outcome of diabetic foot ulcers (DFUs) have investigated various biological materials and recovered molecules that may aid in discriminating wounds that will heal and those that will not heal. This graphical abstract captures the commonly studied classes of biomarkers in the context of DFUs.
Julie Okiro   +6 more
wiley   +1 more source

Effect of Targeted Aspirin Administration Based on First Trimester Combined Screening for Preeclampsia on Preterm Birth: An Interrupted Time Series Analysis

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objectives To assess the effect of an aspirin intervention program on preterm birth (PTB) rates in women identified as high‐risk for preterm preeclampsia in the first‐trimester screening. Design This is a retrospective study evaluating the impact of the intervention program on preterm birth using interrupted time series analysis (ITSA) with an
Monica Minopoli   +5 more
wiley   +1 more source

Platelet function in patients undergoing major non‐cardiac vascular surgery (PLUGS): a prospective cohort study*

open access: yesAnaesthesia, EarlyView.
Summary Introduction Patients who require major vascular surgery often receive antiplatelet therapy for primary or secondary prevention of cardiovascular disease. Clopidogrel resistance and variability in platelet recovery after drug discontinuation pose clinical challenges, particularly for regional anaesthesia and blood management.
Akshay Shah   +11 more
wiley   +1 more source

The Challenges and Benefits of an Open Anterior Repair of Recurrent Inguinal Hernias: A Cohort Study

open access: yesANZ Journal of Surgery, EarlyView.
ABSTRACT Introduction Recurrent inguinal hernia repair presents unique clinical challenges. While minimally invasive surgery (MIS) is often preferred, open anterior mesh repair is a valid approach particularly when requiring mesh, suture, or tack removal. This study evaluates the outcomes of a small incision open anterior mesh repair, including foreign
Marie‐Alexandre Adom   +5 more
wiley   +1 more source

Periodontitis and atherosclerotic cardiovascular disease: A critical appraisal

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract In spite of intensive research efforts driving spectacular advances in terms of prevention and treatments, cardiovascular diseases (CVDs) remain a leading health burden, accounting for 32% of all deaths (World Health Organization. “Cardiovascular Diseases (CVDs).” WHO, February 1, 2017, https://www.who.int/news‐room/fact‐sheets/detail ...
Maria Clotilde Carra   +3 more
wiley   +1 more source

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