In patients with atherothrombotic disease on antithrombotic therapy, P‐CABs demonstrated a significantly superior protective effect against clinically significant upper GI haemorrhage compared to PPIs (aHR 0.22; p = 0.016). This real‐world study highlights P‐CABs as a more potent gastroprotective strategy for high‐risk populations requiring intensive ...
Min Joo Yoon +6 more
wiley +1 more source
A Multicenter Propensity Score-Matched Cohort Study of Preoperative Antiplatelet Therapy and Postoperative Outcomes in Elderly Surgical Patients. [PDF]
Song S +16 more
europepmc +1 more source
De‐Implementing Low‐Value Care in Dentistry: The Case for Choosing Wisely Campaigns
ABSTRACT De‐implementation refers to the practice within implementation science that targets reducing low‐value care; that is practices that have been proven to be outdated, unnecessary, potentially harmful and in some cases not cost‐efficient. Reducing and removing habitual practices, as well as introducing new care, is not easy, as there are multiple
Fabio Arriola‐Pacheco +3 more
wiley +1 more source
Challenges and prospects of <i>CYP2C19</i> genotype-guided clopidogrel therapy from the perspective of precision medicine. [PDF]
Wang Z, Fu X, Zhang G.
europepmc +1 more source
The nature of antiplatelet activity in antilymphoblast ALG--with special reference to cross-reacting antibody, immunochemical characterization, and Coombs' positive thrombocytopenia in ALG-treated renal recipients. [PDF]
Amemiya, H +4 more
core
Garadacimab for the long‐term prophylaxis of hereditary angioedema
Summary Hereditary angioedema (HAE), a rare and debilitating disease characterized by recurrent and spontaneous attacks of tissue swelling, has a high unmet therapeutic need, with many patients experiencing insufficient disease control with current prophylactic treatments.
Emel Aygören‐Pürsün +5 more
wiley +1 more source
Endovascular management of tandem occlusions: current evidence and future directions. [PDF]
Krothapalli N +6 more
europepmc +1 more source
The burden of diabetic foot ulcers in a multi‐ethnic Asian cohort
Abstract Aims Diabetic foot ulcers (DFUs) are a major source of morbidity among individuals with diabetes mellitus (DM), imposing a substantial burden on healthcare systems. Our institution established a multidisciplinary service aiming to facilitate early specialist intervention for DFU management.
Zongwen Wee +2 more
wiley +1 more source
Antithrombotic agents for secondary ischemic stroke prevention in cancer patients with atrial fibrillation: A tertiary medical center retrospective study. [PDF]
Yu CW +5 more
europepmc +1 more source
ABSTRACT Aims Sodium‐glucose cotransporter 2 inhibitors (SGLT2is) improve glycaemic control and cardiorenal outcomes in Type 2 diabetes, particularly in patients at elevated cardiovascular and kidney risk, yet discontinuation following infections appears common.
Christine Ljungberg +5 more
wiley +1 more source

