Results 221 to 230 of about 249,854 (357)

Emergence of institutional antithrombotic protocols for coronavirus 2019

open access: yesResearch and Practice in Thrombosis and Haemostasis, 2020
Kevin P. Cohoon   +3 more
doaj   +1 more source

GLP‐1 Receptor Agonist Therapy and Cardiorenal Outcomes in Type 1 Diabetes: A Propensity‐Matched Real‐World Analysis

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Evidence on cardiovascular/renal outcomes associated with GLP‐1‐based therapies in type 1 diabetes (T1D) is limited. We examined the effects of GLP‐1‐based therapy on major clinical outcomes and safety, including diabetic ketoacidosis (DKA) and hypoglycemia risk, in adults with T1D in a large real‐world cohort.
Anastasios Tentolouris   +7 more
wiley   +1 more source

Indobufen versus Aspirin After CABG in Septuagenarians: A Propensity Score-Matched Cohort Study. [PDF]

open access: yesClin Interv Aging
Yang L   +7 more
europepmc   +1 more source

Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy.

open access: yesJournal of the American Medical Association (JAMA), 2009
A. Shuldiner   +16 more
semanticscholar   +1 more source

ALOX15 mediates thrombin‐induced myristoylation, trafficking, and interaction of protease‐activated receptors, leading to platelet activation and hemostasis

open access: yesThe FEBS Journal, EarlyView.
The role of PARs in platelet function is fairly known; however, the underlying mechanisms are not fully understood. We report that thrombin myristoylates PAR4 in mouse platelets and PAR1 and PAR4 in human platelets, facilitating their membrane transport and interaction, leading to PAR3/4 heterodimers in mice and PAR1/4 heterodimers in humans.
Suresh Govatati   +4 more
wiley   +1 more source

Clopidogrel use is associated with an increased prevalence of Parkinson's disease, particularly among US adults with diabetes. [PDF]

open access: yesClin Park Relat Disord
Zhan J   +8 more
europepmc   +1 more source

Multisite Investigation of Outcomes With Implementation of CYP2C19 Genotype-Guided Antiplatelet Therapy After Percutaneous Coronary Intervention.

open access: yesJACC: Cardiovascular Interventions, 2018
L. Cavallari   +64 more
semanticscholar   +1 more source

Proteolytic remodelling of the extracellular matrix by pericytes

open access: yesThe FEBS Journal, EarlyView.
Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard   +4 more
wiley   +1 more source

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