Results 251 to 260 of about 101,135 (306)
Perioperative antiplatelet therapy.
American family physician, 2010 Aspirin is recommended as a lifelong therapy that should never be interrupted for patients with cardiovascular dis- ease. Clopidogrel therapy is mandatory for six weeks after placement of bare-metal stents, three to six months after myocardial infarction, and at least 12 months after placement of drug-eluting stents.
Chassot, P G +3 more
core +4 more sources
Antiplatelet Therapy Improves the Prognosis of Patients with Hepatocellular Carcinoma
Cancers, 2020 Aims: Antiplatelet therapy has been reported to reduce liver fibrosis and hepatocellular carcinoma (HCC), and has exhibited antitumor properties in other cancers. However, the effects of antiplatelet therapy after diagnosis of HCC are unknown.
Tsuguru Hayashi +2 more
exaly +2 more sources
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Antiplatelet therapy and anticoagulants
The Lancet, 201324 www.thelancet.com Vol 382 July 6, 2013 In the WOEST trial, Willem Dewilde and colleagues assess antithrombotic therapy for patients taking oral anticoagulants and receiving a coronary stent. They suggest that for patients undergoing percutaneous coronary intervention and receiving oral anticoagulants and clopidogrel, adding aspirin is harmful.
Bartosz, Hudzik +2 more
openaire +4 more sources
Antiplatelet therapy in children
Thrombosis Research, 2006Platelets are essential for the maintenance of vascular integrity and control of bleeding at sites of injury, but they are also implicated in the progression of atherosclerotic lesions and arterial vascular thrombosis. The use of antiplatelet drugs for the primary and secondary prevention of cardiovascular and cerebrovascular thromboses in adult ...
Israels, Sara J., Michelson, Alan D.
openaire +3 more sources
Antiplatelet Therapy in Neurointervention
Seminars in Neurology, 2023AbstractThe aim of this review is to provide an overview of the use of antiplatelet medication in neurointervention, with a focus on the clinical indications for antiplatelet use in both preventing and reducing platelet aggregation. This review will cover current antiplatelet medications, pharmacokinetics, and pharmacodynamics.
Alice Ma +12 more
openaire +3 more sources
Pharmacogenetics of Antiplatelet Therapy
Current Atherosclerosis Reports, 2014There has been substantial progress toward understanding and investigating the specific genetic factors that influence interindividual variations in platelet-directed therapy. There has also been substantial progress toward better understanding of the pharmacogenetics of drug metabolism and phamacodynamic response to platelet antagonists.
Patrick L, Daly, Richard C, Becker
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Clinics in Haematology, 1981
Much new information has been gleaned about the morphology, biochemistry and function of platelets. The pathophysiology of atherosclerosis and thromboembolic disorders appears to be related to abnormal platelet function. Endothelial damage, thromboxane A2, Thrombin, adenosine diphospate and epinephrine may each promote platelet aggregation, whereas ...
openaire +4 more sources
Much new information has been gleaned about the morphology, biochemistry and function of platelets. The pathophysiology of atherosclerosis and thromboembolic disorders appears to be related to abnormal platelet function. Endothelial damage, thromboxane A2, Thrombin, adenosine diphospate and epinephrine may each promote platelet aggregation, whereas ...
openaire +4 more sources
Current Atherosclerosis Reports, 2011
Advances in antiplatelet therapy have significantly improved outcomes in patients with ischemic heart disease. Thienopyridines remain a cornerstone of therapy along with aspirin. Recently, concerns have been raised about the use of clopidogrel due to its pharmacokinetic and pharmacogenetic interpatient variability.
Luke, Kim +3 more
openaire +2 more sources
Advances in antiplatelet therapy have significantly improved outcomes in patients with ischemic heart disease. Thienopyridines remain a cornerstone of therapy along with aspirin. Recently, concerns have been raised about the use of clopidogrel due to its pharmacokinetic and pharmacogenetic interpatient variability.
Luke, Kim +3 more
openaire +2 more sources
Antiplatelet therapy in cardiology
Clinical Medicine (Russian Journal), 2016Platelets are important components of hemostasis and play a key role in the formation of atherothrombosis. Rupture or erosion of atherosclerotic plaque gives rise to a thrombus with the involvement of platelets. Antiplatelet agents are instrumental in preventing the development of atherothrombosis of different localization, including coronary arteries.
L V, Popova +2 more
openaire +2 more sources