Results 41 to 50 of about 102,499 (199)

Lactarius deliciosus Extract from Green Microwave-Assisted Eutectic Solvent Extraction as a Therapeutic Candidate Against Colon Cancer

open access: yesAntioxidants
Lactarius deliciosus is a widely distributed edible mushroom valued as a functional food due to its rich content of nutrients, phenolic compounds, and flavonoids, which contribute to its strong antioxidant and antimicrobial properties.
Seyed Hesamoddin Bidooki   +9 more
doaj   +1 more source

Synthesis and Structure Determination of Substituted Thiazole Derivatives as EGFR/BRAFV600E Dual Inhibitors Endowed with Antiproliferative Activity

open access: yesPharmaceuticals, 2023
2,3,4-trisubstituted thiazoles 3a–i, having a methyl group in position four, were synthesized by the reaction of 1,4-disubstituted thiosemicarbazides with chloroacetone in ethyl acetate/Et3N at room temperature or in ethanol under reflux.
Lamya H. Al-Wahaibi   +7 more
doaj   +1 more source

Supplementary Data from The Green Tea Polyphenol EGCG Potentiates the Antiproliferative Activity of c-Met and Epidermal Growth Factor Receptor Inhibitors in Non–small Cell Lung Cancer Cells [PDF]

open access: gold, 2023
Shawn A. Milligan   +7 more
openalex   +1 more source

Cytotoxic and Antioxidant Potential of Launaea mucronata Forssk Essential Oil Growing in Northern Saudi Arabia

open access: yesMolecules, 2023
Essential oils are naturally occurring multicomponent combinations of isoprenoids with distinctive odors that are produced by aromatic plants from mevalonic acid. They are extensively applied in aromatherapy for the treatment of various ailments.
Ehab M. Mostafa   +7 more
doaj   +1 more source

Benzoxazole derivatives as new VEGFR-2 inhibitors and apoptosis inducers: design, synthesis, in silico studies, and antiproliferative evaluation [PDF]

open access: gold, 2022
Mohammed S. Taghour   +11 more
openalex   +1 more source

Fused Xanthone Derivatives as Antiproliferative Agents

open access: yesAnti-Cancer Agents in Medicinal Chemistry, 2009
Xanthones have been isolated from several natural sources, mainly belonging in Guttiferae and Gentianaceae families as secondary plant metabolites and many of them are endowed with diverse pharmacological properties. We have focused in the study of cytotoxic fused xanthone derivatives, having in mind that some furano- and pyranoxanthone natural ...
Pouli, N., Marakos, P.
openaire   +3 more sources

Novel perylene diimide based antiproliferative chromophores

open access: yesBalıkesir Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2023
The primary objective of the work was to monitor the antiproliferative activity of two newly synthesized and described perylene diimides. The MTT test was used to investigate the antiproliferative effect against PC3 the prostat cancer cell line, Panc1 pancreatic cancer cell line, Saos2 osteosarcoma cell line, Hep3B hepatoma cell line and HUVEC non ...
Furkan OZCİL   +3 more
openaire   +2 more sources

Lenalidomide, an antiproliferative CLL drug

open access: yesBlood, 2014
In this issue of Blood , Fecteau et al show that lenalidomide inhibits proliferation of chronic lymphocytic leukemia (CLL) cells in vitro by targeting cereblon. Thus far, the clinical activity of this drug in CLL was believed to be mainly via the microenvironment.[1][1] ![Figure][2 ...
openaire   +3 more sources

Antiproliferative Withanolides from Datura wrightii [PDF]

open access: yesJournal of Natural Products, 2012
A new withanolide, named withawrightolide (1), and four known withanolides (2-5) were isolated from the aerial parts of Datura wrightii. The structure of compound 1 was elucidated through 2D NMR and other spectroscopic techniques. In addition, the structure of withametelin L (2) was confirmed by X-ray crystallographic analysis.
Zhang, Huaping   +8 more
openaire   +3 more sources

Corrigendum: Impact of a TAK-1 inhibitor as a single or as an add-on therapy to riociguat on the metabolic reprograming and pulmonary hypertension in the SUGEN5416/hypoxia rat model

open access: yesFrontiers in Pharmacology, 2023
Daniel Morales-Cano   +35 more
doaj   +1 more source

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