Results 21 to 30 of about 186,437 (313)
Synthesis of Hydantoin Androgen Receptor Antagonists and Study on Their Antagonistic Activity
Molecules, 2022 Hydroxymethylthiohydantoin, hydroxymethylthiohydantoin, and hydantoin, containing a pyridine group, were synthesized to study their androgen receptor antagonistic activities.
Longjun Ma +5 more
doaj +1 more source
Anthocyanin absorption and metabolism by human intestinal Caco-2 cells: a review [PDF]
, 2015 Anthocyanins from different plant sources have been shown to possess health beneficial effects against a number of chronic diseases. To obtain any influence in a specific tissue or organ, these bioactive compounds must be bioavailable, i.e., effectively ...
Battino, Maurizioeditor +4 more
core +3 more sources
Antiproliferative Trihydroxyalkylcyclohexenones from Pleiogynium timoriense [PDF]
Journal of Natural Products, 2015 Investigation of a DCM extract of the bark of Pleiogynium timoriense from the former Merck collection of natural product extracts for antiproliferative activity indicated that it was active with an IC50 value of 1.3 μg/mL against the A2780 ovarian cancer cell line.
Eaton, A. L. +4 more
openaire +2 more sources
Pharmaceuticals, 2022 The antiproliferative effects played by benzothiazoles in different cancers have aroused the interest for these molecules as promising antitumor agents.
Rosa Amoroso +12 more
doaj +1 more source
Sirtuin functions and modulation: from chemistry to the clinic [PDF]
, 2016 Sirtuins are NAD+ -dependent histone deacetylases regulating important metabolic pathways in prokaryotes and eukaryotes and are involved in many biological processes such as cell survival, senescence, proliferation, apoptosis, DNA repair, cell ...
Altucci, Lucia +9 more
core +2 more sources
Pharmaceuticals, 2020 Cancer accounts for one of the most complex diseases nowadays due to its multifactorial nature. Despite the vast number of cytotoxic agents developed so far, good therapeutic approaches are not always reached.
Paloma Begines +9 more
doaj +1 more source
Antioxidants, 2022 Selaginella doederleinii Hieron. (S. doederleinii) is a traditional herb that is widely used in China to treat several ailments, but mainly cancer. Studies have been carried out to determine the phytochemicals ascribed to its pharmacological activity ...
Felix Wambua Muema +4 more
doaj +1 more source
Synthesis of nine safrole derivatives and their antiproliferative activity towards human cancer cells [PDF]
, 2010 Indexación: ScieloSafrole from sassafras oil (Ocoteapretiosa Mez., Lauraceae), is an abundant natural product showing interesting functionality and chemical structure.
Carrasco Altamirano, Héctor +5 more
core +2 more sources
Antioxidants, 2020 Cassia fistula L. is a highly admirable traditional medicinal plant used for the treatment of various diseases and disorders. The present study was performed to divulge the antioxidant, antiproliferative, and apoptosis-inducing efficacy of fractions from
Sandeep Kaur +11 more
doaj +1 more source
Pharmaceuticals, 2021 Ficus glumosa Delile (Moraceae), a reputed plant that is used in herbal medicine, is of high medicinal and nutritional value in local communities primarily ascribed to its phytochemical profile.
Moses Mutuse Mutungi +6 more
doaj +1 more source