A QSAR Study on the 4-Substituted Coumarins as Potent Tubulin Polymerization Inhibitors [PDF]
Advanced Pharmaceutical Bulletin, 2020 Purpose: Despite the discovery and synthesis of several anticancer drugs, cancer is still a major life threatening incident for human beings after cardiovascular diseases.
Leila Dinparast, Siavoush Dastmalchi
doaj +1 more source
Molecules, 2021 Chemical and biological investigation of the Madagascar endemic plant Saldinia proboscidea led to the isolation of an isomer of artemisinin, (−)-6-epi-artemisinin (2). Its structure was elucidated using a combination of NMR and mass spectrometry.
Saholinirina Randrianarivo +6 more
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Original Multivalent Gold (III) and Dual Gold(III)-Copper(II) Conjugated Phosphorus Dendrimers as Potent Antitumoral and Antimicrobial Agents [PDF]
, 2017 Original metallophosphorus dendrimers (generation 3, 48 terminal groups) have been prepared via the complexation of phosphorus dendrimers bearing imino-pyridino end groups with Au(III) or with both Au(III) and Cu(II).
Anne-Marie Caminade +11 more
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The novel mTOR inhibitor RAD001 (Everolimus) induces antiproliferative effects in human pancreatic neuroendocrine tumor cells [PDF]
, 2007 Background/Aim: Tumors exhibiting constitutively activated PI(3) K/Akt/mTOR signaling are hypersensitive to mTOR inhibitors such as RAD001 (everolimus) which is presently being investigated in clinical phase II trials in various tumor entities, including
Albert JM +35 more
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UJI SITOTOKSITAS DAN ANTIPROLIFERATIF SEL KANKER PAYUDARA T47D DAN SEL VERO BIJI Nigella sativa, L.
Pharmaciana, 2012 Black cumin seeds contain oil classes atisiri, terpenes, and alkaloids that can be used for traditional medicine as anticancer. The purpose of this study was to assess the cytotoxic effects of ether extract, ethanol, and infusa seed Nigella sativa, L ...
Laela Hayu Nurani
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Chemical investigation of a biologically active schinus molle L. leaf extract [PDF]
, 2019 The pepper tree Schinus molle L. is an evergreen ornamental plant belonging to the Anacardiaceae family, native to South America and widespread throughout the world. It has biological activities and is used in folk medicine. This paper aims to contribute
Garzoli, S. +5 more
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Sirtuin functions and modulation: from chemistry to the clinic [PDF]
, 2016 Sirtuins are NAD+ -dependent histone deacetylases regulating important metabolic pathways in prokaryotes and eukaryotes and are involved in many biological processes such as cell survival, senescence, proliferation, apoptosis, DNA repair, cell ...
Altucci, Lucia +9 more
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Antiproliferative Effect of Indole Phytoalexins [PDF]
Molecules, 2016 Indole phytoalexins from crucifers have been shown to exhibit significant anti-cancer, chemopreventive, and antiproliferative activity. Phytoalexins are natural low molecular antimicrobial compounds that are synthesized and accumulated in plants after their exposure to pathogenic microorganisms. Most interestingly, crucifers appear to be the only plant
Martina Chripkova +2 more
openaire +3 more sources
Applied Sciences, 2022 The phytochemical compositions of green coffee beans (GB), roasted coffee (RC), and the solid residue known as spent coffee grounds (SCG) have been associated with beneficial physiological effects.
Gema C. Díaz-Hernández +7 more
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Antioxidant and antiproliferative activities of the essential oils from Thymbra capitata and Thymus Species grown in Portugal [PDF]
, 2015 The antioxidant and antiproliferative activities of the essential oils from Thymbra capitata and Thymus species grown in Portugal were evaluated. Thymbra and Thymus essential oils were grouped into two clusters: Cluster I in which carvacrol, thymol, p ...
Antunes, Maria Dulce +7 more
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