New selenosteroids as antiproliferative agents
Organic & Biomolecular Chemistry, 2017 A wide panel of new selenosteroids have been prepared as new antiproliferative agents; improved activities were achieved compared to commonly-used chemotherapeutic agents.
Fuentes-Aguilar, Alma +10 more
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Lipophilic modification of Salirasib modulate the antiproliferative and antimigratory activity. [PDF]
, 2023 Salirasib, or farnesylthiosalicylic acid (FTS), is a salicylic acid derivative with demonstrated antineoplastic activity. While designed as a competitor of the substrate S-farnesyl cysteine on Ras, it is a potent competitive inhibitor of ...
Exequiel O. J., Porta +6 more
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In vitro antiproliferative and antioxidant activity of three fungal strains from the White sea
, 2021 Fungi have been recognized as a prolific source of bioactive compounds with a wide spectrum of bioactivities, nevertheless, the information about marine polar fungi is scarce.
Alla V. Shnyreva +11 more
core +1 more source
Antiproliferative Activity of Fucan Nanogel [PDF]
Marine Drugs, 2012 Sulfated fucans comprise families of polydisperse natural polysaccharides based on sulfated l-fucose. Our aim was to investigate whether fucan nanogel induces cell-specific responses. To that end, a non toxic fucan extracted from Spatoglossum schröederi was chemically modified by grafting hexadecylamine to the polymer hydrophilic backbone.
Nednaldo Dantas-Santos +8 more
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Novel Methylselenoesters as Antiproliferative Agents [PDF]
Molecules, 2017 Selenium (Se) compounds are potential therapeutic agents in cancer. Importantly, the biological effects of Se compounds are exerted by their metabolites, with methylselenol (CH3SeH) being one of the key executors. In this study, we developed a new series of methylselenoesters with different scaffolds aiming to modulate the release of CH3SeH.
Nuria Díaz-Argelich +5 more
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UJI SITOTOKSITAS DAN ANTIPROLIFERATIF SEL KANKER PAYUDARA T47D DAN SEL VERO BIJI Nigella sativa, L.
Pharmaciana, 2012 Black cumin seeds contain oil classes atisiri, terpenes, and alkaloids that can be used for traditional medicine as anticancer. The purpose of this study was to assess the cytotoxic effects of ether extract, ethanol, and infusa seed Nigella sativa, L ...
Laela Hayu Nurani
doaj +1 more source
Applied Sciences, 2022 The phytochemical compositions of green coffee beans (GB), roasted coffee (RC), and the solid residue known as spent coffee grounds (SCG) have been associated with beneficial physiological effects.
Gema C. Díaz-Hernández +7 more
doaj +1 more source
Synthesis and Evaluation of the Tetracyclic Ring-System of Isocryptolepine and Regioiso-Mers for Antimalarial, Antiproliferative and Antimicrobial Activities [PDF]
, 2021 A series of novel quinoline-based tetracyclic ring-systems were synthesized and evaluated in vitro for their antiplasmodial, antiproliferative and antimicrobial activities.
Jeanette H. Andersen +28 more
core +1 more source
Synthesis of Hydantoin Androgen Receptor Antagonists and Study on Their Antagonistic Activity
Molecules, 2022 Hydroxymethylthiohydantoin, hydroxymethylthiohydantoin, and hydantoin, containing a pyridine group, were synthesized to study their androgen receptor antagonistic activities.
Longjun Ma +5 more
doaj +1 more source
Total phenolic content, FTIR analysis, and antiproliferative evaluation of lupin seeds harvest from western Romania [PDF]
, 2017 Introduction Lupinus spp. are herbaceous perennial flowering plants included in the Fabaceae family. Among the approximately 200 species belonging to this genre, Lupinus albus L., also known as white lupin, Lupinus angustifolius L., and narrow-leafed ...
Babuta, Roxana +18 more
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