Results 11 to 20 of about 136,781 (306)

New selenosteroids as antiproliferative agents

open access: yesOrganic & Biomolecular Chemistry, 2017
A wide panel of new selenosteroids have been prepared as new antiproliferative agents; improved activities were achieved compared to commonly-used chemotherapeutic agents.
Penélope Merino-Montiel   +10 more
core   +4 more sources

Antiproliferative effects of peracetylated naphthoxylosides

open access: yesBioorganic & Medicinal Chemistry Letters, 2009
The antiproliferative activity, and the capability of priming of glycosaminoglycan chains, of two series of peracetylated mono- and bis-xylosylated dihydroxynaphthalenes have been investigated for normal HFL-1 cells, as well as transformed T24 cells, and
Jacobsson, Mårten,   +5 more
core   +4 more sources

In vitro antiproliferative and antioxidant activity of three fungal strains from the White sea

open access: yes, 2021
Fungi have been recognized as a prolific source of bioactive compounds with a wide spectrum of bioactivities, nevertheless, the information about marine polar fungi is scarce.
Alla V. Shnyreva   +11 more
core   +1 more source

Novel Methylselenoesters as Antiproliferative Agents [PDF]

open access: yesMolecules, 2017
Selenium (Se) compounds are potential therapeutic agents in cancer. Importantly, the biological effects of Se compounds are exerted by their metabolites, with methylselenol (CH3SeH) being one of the key executors. In this study, we developed a new series of methylselenoesters with different scaffolds aiming to modulate the release of CH3SeH.
Nuria Díaz-Argelich   +5 more
openaire   +4 more sources

Lipophilic modification of Salirasib modulate the antiproliferative and antimigratory activity. [PDF]

open access: yes, 2023
Salirasib, or farnesylthiosalicylic acid (FTS), is a salicylic acid derivative with demonstrated antineoplastic activity. While designed as a competitor of the substrate S-farnesyl cysteine on Ras, it is a potent competitive inhibitor of ...
Exequiel O. J., Porta   +6 more
core   +2 more sources

Antiproliferative effect of metformin on the endometrium [PDF]

open access: yes, 2015
Antiproliferative effect of metformin on the ...
Svetlana Igorevna Andreeva
core   +1 more source

Antiproliferative Activity of Fucan Nanogel [PDF]

open access: yesMarine Drugs, 2012
Sulfated fucans comprise families of polydisperse natural polysaccharides based on sulfated l-fucose. Our aim was to investigate whether fucan nanogel induces cell-specific responses. To that end, a non toxic fucan extracted from Spatoglossum schröederi was chemically modified by grafting hexadecylamine to the polymer hydrophilic backbone.
Nednaldo Dantas-Santos   +8 more
openaire   +4 more sources

Antibacterial, Antiradical and Antiproliferative Potential of Green, Roasted, and Spent Coffee Extracts

open access: yesApplied Sciences, 2022
The phytochemical compositions of green coffee beans (GB), roasted coffee (RC), and the solid residue known as spent coffee grounds (SCG) have been associated with beneficial physiological effects.
Gema C. Díaz-Hernández   +7 more
doaj   +1 more source

Total phenolic content, FTIR analysis, and antiproliferative evaluation of lupin seeds harvest from western Romania [PDF]

open access: yes, 2017
Introduction Lupinus spp. are herbaceous perennial flowering plants included in the Fabaceae family. Among the approximately 200 species belonging to this genre, Lupinus albus L., also known as white lupin, Lupinus angustifolius L., and narrow-leafed ...
Babuta, Roxana   +18 more
core   +2 more sources

Synthesis of Hydantoin Androgen Receptor Antagonists and Study on Their Antagonistic Activity

open access: yesMolecules, 2022
Hydroxymethylthiohydantoin, hydroxymethylthiohydantoin, and hydantoin, containing a pyridine group, were synthesized to study their androgen receptor antagonistic activities.
Longjun Ma   +5 more
doaj   +1 more source

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