Results 51 to 60 of about 132,199 (306)

Synthesis, characterization and antiproliferative activity of hexa arm star shaped thiosemicarbazones derived from cyclotriphosphazene core

, 2014
A series of novel hexa-arm star shaped thiosemicarbazones with different substitutions at para positions emanating from cyclotriphosphazene core were prepared with excellent yields.
Patil, B.R., Machakanur, S.S., Bakale, R.P., Naik, G.N., Bligh, S.W.A., Gudasi, K.B.   +5 more
core   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Myrciaria tenella (DC.) O. Berg (Myrtaceae) Leaves as a Source of Antioxidant Compounds

Antioxidants, 2019
Myrciaria species are widely studied to identify their chemical composition and evaluate their biological activity. Since evidence supporting the potential antioxidant and antiproliferative activity of Myrciaria tenella is lacking, the aim of this work ...
Ana Raquel Carneiro Ribeiro, Maria Lúcia da Silva Cordeiro, Larissa Marina Pereira Silva, Cesar Orlando Munoz Cadavid, Ricardo Basílio de Oliveira Caland, Marília Medeiros Fernandes-Negreiros, Moacir Fernandes Queiroz, Jefferson da Silva Barbosa, Cicero Flavio Soares Aragão, Silvana Maria Zucolotto, Riva de Paula Oliveira, Hugo Alexandre Oliveira Rocha, Kátia Castanho Scortecci   +12 more
doaj   +1 more source

How is Nanoarchitectonics Shaping Extracellular Vesicle Research?

Advanced Healthcare Materials, EarlyView.
The convergence of nanoarchitectonics and extracellular vesicle biology is reshaping next‐generation nanomedicine by enabling rationally designed nanostructures for enhanced EVs detection, engineering, and therapy. ABSTRACT Extracellular vesicles (EVs) have gained recognition as crucial mediators of cell‐to‐cell communication, holding immense potential
Madushani Dahanayake, Md Shahriar A. Hossain, Chia‐Hung Liu, Carlos Salomon, Yusuke Yamauchi, Mostafa Kamal Masud   +5 more
wiley   +1 more source

Lactarius deliciosus Extract from Green Microwave-Assisted Eutectic Solvent Extraction as a Therapeutic Candidate Against Colon Cancer

Antioxidants
Lactarius deliciosus is a widely distributed edible mushroom valued as a functional food due to its rich content of nutrients, phenolic compounds, and flavonoids, which contribute to its strong antioxidant and antimicrobial properties.
Seyed Hesamoddin Bidooki, Beatriz Rodríguez-Martínez, Javier Quero, Luis Vicente Herrera-Marcos, Mónica Paesa, Marina Delgado-Machuca, Oscar F. Beas-Guzmán, Jesús Osada, Pedro Ferreira-Santos, María Jesús Rodríguez-Yoldi   +9 more
doaj   +1 more source

Synthesis and Structure Determination of Substituted Thiazole Derivatives as EGFR/BRAF^V600E Dual Inhibitors Endowed with Antiproliferative Activity

Pharmaceuticals, 2023
2,3,4-trisubstituted thiazoles 3a–i, having a methyl group in position four, were synthesized by the reaction of 1,4-disubstituted thiosemicarbazides with chloroacetone in ethyl acetate/Et3N at room temperature or in ethanol under reflux.
Lamya H. Al-Wahaibi, Essmat M. El-Sheref, Alaa A. Hassan, S. Bräse, M. Nieger, Bahaa G. M. Youssif, Mahmoud A. A. Ibrahim, Hendawy N. Tawfeek   +7 more
doaj   +1 more source

Magnetically Driven Biofabrication for Tissue Engineering: From Nanoparticle Design to Mag‐ATMP Translation

Advanced Healthcare Materials, EarlyView.
Magnetically responsive nanoparticles enable remote control over biomaterials, cells, and engineered tissues. This review summarizes material design, biological safety, fabrication and actuation strategies, computational validation, and translational pathways that support the development of magnetic tissue‐engineering platforms and future magnetically ...
Konstantinos Ioannidis, Dimitrios Lefas, Maya Guilliams, Jackie Van Grootenbril, Isaak Decoene, Dimitrios Sakellariou, Bart Smeets, Stefanos Mourdikoudis, Ioannis Papantoniou   +8 more
wiley   +1 more source

Cytotoxic and Antioxidant Potential of Launaea mucronata Forssk Essential Oil Growing in Northern Saudi Arabia

Molecules, 2023
Essential oils are naturally occurring multicomponent combinations of isoprenoids with distinctive odors that are produced by aromatic plants from mevalonic acid. They are extensively applied in aromatherapy for the treatment of various ailments.
Ehab M. Mostafa, Ahmed H. El-Ghorab, Mohammed M. Ghoneim, Hasnaa Ali Ebrahim, Moaz Abulfaraj, Mohamed A. Abdelgawad, Amr Farouk, Arafa Musa   +7 more
doaj   +1 more source

Antiproliferative Effect of pHLIP-Amanitin

Biochemistry, 2013
Toxins could be effective anticancer drugs, if their selective delivery into cancer cells could be achieved. We have shown that the energy of membrane-associated folding of water-soluble membrane peptides of the pHLIP (pH low insertion peptide) family could be used to move cell-impermeable cargo across the lipid bilayer into the cytoplasm of cancer ...
Moshnikova, Anna, Moshnikova, Valentina, Andreev, Oleg A., Reshetnyak, Yana   +3 more
openaire   +4 more sources

Willd. and antiproliferative activities of extracts

, 2023
The aerial parts of Nepeta teucriifolia Willd. were extracted with the solvents of different polarities. The antiproliferative activities of the extracts were evaluated against rat brain tumor (C6) and human cervix carcinoma (HeLa) cell lines.
Ebru Aktas, Ibrahim Demirtas, Demirtas, Ibrahim, Behcet, Lutfi, Ferda Eser, Muhammed Altun, Altun, Muhammed, Aktas, Ebru, Eser, Ferda, Lutfi Behcet   +9 more
core   +1 more source