Results 11 to 20 of about 1,343 (198)

Fermented lingonberry juice's effects on active MMP-8 (aMMP-8), bleeding on probing (BOP), and visible plaque index (VPI) in dental implants-A clinical pilot mouthwash study [PDF]

Clinical and Experimental Dental Research, Volume 8, Issue 6, Page 1322-1330, December 2022., 2022
Objectives: We aimed to study the effects of fermented lingonberry juice (FLJ) as a mouthwash on the levels of active matrix metalloproteinase-8 (aMMP-8) in peri-implant sulcular fluid (PISF), bleeding on probing (BOP), and visible plaque index (VPI). We
Lähteenmäki, Hanna, Pärnänen, Pirjo, Räisänen, Ismo T., Sorsa, Timo, Tervahartiala, Taina   +4 more
core   +2 more sources

SOD1 Protein Content in Human Central Nervous System and Peripheral Tissues. [PDF]

J Neurochem
Disease‐modifying treatments targeting the core pathological process for SOD1‐linked amyotrophic lateral sclerosis (ALS) are becoming available. Much evidence suggests that misfolding and aggregation of the SOD1 protein cause proteotoxicity, and inhibition of SOD1 expression shows a good effect in many ALS patients.
Leykam L, Jonsson PA, Forsberg KME, Andersen PM, Brännström T, Marklund SL, Zetterström P.   +6 more
europepmc   +2 more sources

Food, gut barrier dysfunction, and related diseases: A new target for future individualized disease prevention and management

Food Science &Nutrition, Volume 11, Issue 4, Page 1671-1704, April 2023., 2023
Abstract Dysfunction of gut barrier is known as “leaky gut” or increased intestinal permeability. Numerous recent scientific evidences showed the association between gut dysfunction and multiple gastrointestinal tract (GI) and non‐GI diseases. Research also demonstrated that food plays a crucial role to cause or remedy gut dysfunction related to ...
Linda Liang, Clarissa Saunders, Nerses Sanossian   +2 more
wiley   +1 more source

Biological Flora of Britain and Ireland: Knautia arvensis

Journal of Ecology, Volume 110, Issue 8, Page 1970-1992, August 2022., 2022
Field Scabious is a widespread, native perennial of grasslands and meadows found throughout much of Europe. It is a popular plant frequently used as part of pollinator seed mixes, as the nectariferous blue‐lilac flowers support a range of generalist and specialist pollinators.
Sandra Varga, Carl D. Soulsbury, Elizabeth A. John   +2 more
wiley   +1 more source

MdVQ37 Negatively Regulates Apple Resistance to Valsa Canker via SA-Dependent and SA-Independent Pathways. [PDF]

Mol Plant Pathol
MdVQ37 negatively regulates apple resistance to Valsa canker by promoting the expression of salicylic acid catabolism genes and inhibiting MdWRKY100‐mediated antioxidant enzyme activity. ABSTRACT Apple Valsa canker is one of the major fungal diseases adversely affecting the apple industry.
Duan D, Zheng W, Shi M, Yi R, Dong Q, Yang J, Ma F, Mao K.   +7 more
europepmc   +2 more sources

Serum cystatin C was a marker of poststroke fatigue in hypertensive intracerebral hemorrhage

Brain and Behavior, Volume 11, Issue 2, February 2021., 2021
High Cys‐C levels have predictive value for PSF and can be used as one screening indicator for PSF occurrence. High admission Cys‐C (>0.75 mg/L) yielded specificity of 93.7%, positive predictive value of 87.5%, and negative predictive value of 88.2%.
Fulan Yang, Peipei Liu, Saiyu Huang, Xiaojie Liu, Xue Gao, Chunyin Liu, Lanlan Chen, Yingzhu Chen   +7 more
wiley   +1 more source

Structure‐Activity Relationships of Benzamides and Isoindolines Designed as SARS‐CoV Protease Inhibitors Effective against SARS‐CoV‐2

ChemMedChem, Volume 16, Issue 2, Page 340-354, January 19, 2021., 2021
Valuable starting points: Within this study, the effectivity of naphthalene‐based inhibitors, formerly developed against the papain‐like protease (PLpro) of the severe acute respiratory syndrome (SARS)‐causing coronavirus (CoV), against the homologous PLpro of SARS‐CoV‐2 is shown. Furthermore, isoindoline is presented as an innovative scaffold for this
Armin Welker, Christian Kersten, Christin Müller, Ramakanth Madhugiri, Collin Zimmer, Patrick Müller, Robert Zimmermann, Stefan Hammerschmidt, Hannah Maus, John Ziebuhr, Christoph Sotriffer, Tanja Schirmeister   +11 more
wiley   +1 more source

The canine activated platelet secretome (CAPS): A translational model of thrombin‐evoked platelet activation response

Research and Practice in Thrombosis and Haemostasis, Volume 5, Issue 1, Page 55-68, January 2021., 2021
Abstract Background Domestic dogs represent a translational animal model to study naturally occurring human disease. Proteomics has emerged as a promising tool for characterizing human platelet pathophysiology; thus a detailed characterization of the core canine activated platelet secretome (CAPS) will enhance utilization of the canine model.
Signe E. Cremer, James L. Catalfamo, Robert Goggs, Stefan E. Seemann, Annemarie T. Kristensen, Paulina B. Szklanna, Patricia B. Maguire, Marjory B. Brooks   +7 more
wiley   +1 more source

Cannabidiol Decreases Metalloproteinase Activity and Normalizes Angiogenesis Factor Expression in UVB‐Irradiated Keratinocytes from Psoriatic Patients

Oxidative Medicine and Cellular Longevity, Volume 2021, Issue 1, 2021., 2021
The development of psoriasis is associated with the consequences of oxidative stress and inflammation leading to metabolic changes locally, in the skin cells, and systemically, in the blood. Therefore, the aim of this study was to analyze the effect of psoriasis vulgaris (PsV) and psoriatic arthritis (PsA) on the basal plasma/keratinocyte levels of ...
Agnieszka Gęgotek, Sinemyiz Atalay, Adam Wroński, Agnieszka Markowska, Elżbieta Skrzydlewska, Przemko Tylzanowski   +5 more
wiley   +1 more source

Endoleak Detection after Endovascular Aortic Aneurysm Repair Using Ultrasound Based on Nanoscale Bubble Contrast Agents and Their Effects on Vascular Smooth Muscle Cell Proliferation and Migration

Journal of Nanomaterials, Volume 2021, Issue 1, 2021., 2021
Abdominal aortic aneurysm (AAA) is the most common vascular disease that causes disability and death. Its morbidity is relatively subtle, and the mortality rate is high. Clinically, endovascular aortic aneurysm repair (EVAR) has gradually become the primary treatment of AAA due to its unique advantages such as low trauma and low incidence of short‐term
Siying Pei, Yao Feng, Shuqing Fang, Song Jin, Dongxu Fan, Fanxu Song, Hanrui Wang, Songwen Tan   +7 more
wiley   +1 more source