Results 41 to 50 of about 1,343 (198)
Cystatin C deficiency in human atherosclerosis and aortic aneurysms [PDF]
, 2014 The pathogenesis of atherosclerosis and abdominal aortic aneurysm involves breakdown of the elastic laminae. Elastolytic cysteine proteases, including cathepsins S and K, are overexpressed at sites of arterial elastin damage, but whether endogenous local
Chapman, Harold A. +8 more
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Ecology and Evolution, Volume 10, Issue 13, Page 6844-6862, July 2020., 2020 The period of hibernation in the brown bear allows it to face the adverse climatic conditions of the scarce of food during the winter. In this study, we review the published literature on this topic and approach it from the perspective of den chronology, den selection, and physiology of hibernation.
Enrique González‐Bernardo +4 more
wiley +1 more source
High level expression of bikunin in Pichia pastoris by fusion of human serum albumin [PDF]
, 2012 Bikunin is a proteoglycan exhibiting broad-spectrum inhibitory activity against serine proteases and could potentially suppress tumor cell invasion and metastasis.
Xing-Hua Gou +7 more
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BioMed Research International, Volume 2020, Issue 1, 2020., 2020 The aim of the study was to determine whether plasma levels of total glycosaminoglycans (GAGs), matrix metalloproteinases (MMPs) (MMP‐3, MMP‐10), and their tissue inhibitors (TIMPs) (TIMP‐1, TIMP‐2) as well as transforming growth factor β (TGF‐β) differ in the patients with systemic sclerosis (SSc) in relation to the healthy subjects.
Kornelia Kuźnik-Trocha +8 more
wiley +1 more source
Brazilian Journal of Medical and Biological Research, 2018 Bredemeyera floribunda roots are popularly used to treat snakebites in the semiarid region of Northeast Brazil, and previous studies indicate the anti-ophidian actions of triterpenoid saponins found in its roots. To assess B.
N.T.Q. Alves +15 more
doaj +1 more source
NEW BIOCHEMICAL MARKERS OF RECURRENCE OF PROSTATE CANCER AFTER HIS TREATMENT
Вестник урологии, 2013 We studied the condition of the blood proteolytic systems (activity of kallikrein (К) and level of prekallikrein (PK), the total proteolytic activity of serine proteinases and elastase-like activity, the leukocytic elastase (LE) activity, the angiotensin-
M. B. Chibichyan +2 more
doaj +1 more source
In vitro and in vivo anticancer properties of a Calcarea carbonica derivative complex (M8) treatment in a murine melanoma model [PDF]
, 2010 Background: Melanoma is the most aggressive form of skin cancer and the most rapidly expanding cancer in terms of worldwide incidence. Chemotherapeutic approaches to treat melanoma have had only marginal success.
Fernando SF Guimarães +46 more
core +2 more sources
Cluster analysis of immunological serum markers in patients with Parkinson’s disease
Анналы клинической и экспериментальной неврологии, 2019 Introduction. The study of patients biological features, including their immune responses, in specific diseases, is an important step towards personalized diagnosis and treatment.
Tatyana P. Klyushnik +4 more
doaj +1 more source
BMC Cell Biology, 2004 Summary Background α1-antitrypsin (AAT) is one of the major serine proteinase inhibitors controlling proteinases in many biological pathways. There is increasing evidence that AAT is able to exert other than antiproteolytic effects.
Jansson Lennart +2 more
doaj +1 more source
Selective amino acid restriction therapy (SAART): a non-pharmacological strategy against all types of cancer cells [PDF]
, 2015 Metastasis will continue to be an incurable disease for most patients until we develop highly selective anticancer therapies. The development of these therapies requires finding and exploiting major differences between cancer cells and normal cells ...
López Lázaro, Miguel
core +2 more sources