Results 71 to 80 of about 1,343 (198)

EFEK ANTIINFLAMASI DOKSISIKLIN TERHADAP VOLUME EKSPIRASI PAKSA DETIK PERTAMA, MATRIKS METALLOPROTEINASE-9 SERUM, DAN HIGH SENSITIF C-REAKTIF PROTEIN SERUM PADA PENATALAKSANAAN PENYAKIT PARU OBSTRUKTIF KRONIK STABIL [PDF]

open access: yes, 2013
Ronike Yunus, 2013.. Tesis. Efek Antiinflamasi Doksisiklin Terhadap Volume Ekspirasi Paksa Detik Pertama, Matriks Metalloproteinase-9 serum, dan High Sensitif C-Reaktif Protein Serum Pada Penyakit Paru Obstruktif Kronik Stabil. Supervisor I: Prof. Dr.
Yunus, Muh. Ronike
core  

Biguanide iridium(III) complexes with potent antimicrobial activity [PDF]

open access: yes, 2018
We have synthesized novel organoiridium(III) antimicrobial complexes containing a chelated biguanide, including the antidiabetic drug metformin. These 16- and 18-electron complexes were characterized by NMR, ESI-MS, elemental analysis, and X-ray ...
Chen, Feng   +8 more
core   +2 more sources

BRCA1 loss activates cathepsin L–mediated degradation of 53BP1 in breast cancer cells [PDF]

open access: yes, 2013
Loss of 53BP1 rescues BRCA1 deficiency and is associated with BRCA1-deficient and triple-negative breast cancers (TNBC) and with resistance to genotoxic drugs.
Abena B. Redwood   +73 more
core   +4 more sources

Putative Involvement of Thiol Protease Inhibitor in the Function of Alzheimer Drug [PDF]

open access: yes, 2019
The intermolecular structure gets altered when drug-protein interaction takes place. It brings about alterations in the conformation of protein. An acetyl cholinesterase inhibitor (AChE) is the most used drug for patients who are suffering from Alzheimer’
Amin, Fakhra, Bano, Bilqees
core   +2 more sources

How proteolytic inhibitors interact with dentin on glass-fiber post luting over 6 months [PDF]

open access: yes, 2018
Objectives: Enzyme inhibitors minimize the degradation of unprotected collagen of dentin promoted by matrix metalloproteinases (MMPs) and cysteine cathepsins (CCs).
Araujo, Diana F. G.   +7 more
core   +1 more source

Chitosan copolymers for intranasal delivery of insulin: synthesis, characterization and biological properties [PDF]

open access: yes, 2004
Recently, chitosan has been extensively investigated as a promising carrier in the field of drug delivery. To overcome its poor solubility at physiological pH and the cytotoxicity of trimethyl chitosan, PEGylated trimethyl chitosan copolymers were ...
Kissel, Thomas (Prof.), Mao, Shirui
core   +1 more source

Molecular Characterization of the Glycated Plasma Membrane Calcium Pump [PDF]

open access: yes, 1999
We have previously demonstrated (Diabetes 39:707–711, 1990) that in vitro glycation of the red cell Ca2+ pump diminishes the Ca2+-ATPase activity of the enzyme up to 50%. Such effect is due to the reaction of glucose with lysine residues of the Ca2+ pump
Castello, Pablo R.   +3 more
core   +1 more source

The urokinase system of plasminogen activation and prognosis in 2780 breast cancer patients [PDF]

open access: yes, 2000
The antigen levels of components of the urokinase-type plasminogen activator (uPA) system of plasminogen activation are correlated with prognosis in several types of cancers, including breast cancer.
Brunner, N.   +11 more
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Improving oncolytic adenoviral therapies for gastrointestinal cancers and tumor initiating cells [PDF]

open access: yes, 2010
Although the treatment of most cancers has improved steadily, only few metastatic solid tumors can be cured. Despite responses, refractory clones often emerge and the disease becomes refractory to available treatment modalities.
Kangasniemi, Lotta
core  

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