Results 141 to 150 of about 8,234 (175)

Synthesis and Antiprotozoal Activity of Aza-Analogues of Furamidine

Journal of Medicinal Chemistry, 2003
6-[5-(4-Amidinophenyl)furan-2-yl]nicotinamidine (8a) was synthesized from 6-[5-(4-cyanophenyl)furan-2-yl]nicotinonitrile (4a), through the bis-O-acetoxyamidoxime followed by hydrogenation. Compound 4a was prepared via selective bromination of 6-(furan-2-yl)nicotinonitrile (2a) with N-bromosuccinimide, followed by Suzuki coupling with 4 ...
Mohamed A, Ismail, Reto, Brun, Judy D, Easterbrook, Farial A, Tanious, W David, Wilson, David W, Boykin   +5 more
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Screening of plant extracts for antiprotozoal and cytotoxic activities

Journal of Ethnopharmacology, 2003
Methanolic and aqueous extracts derived from 43 plant species, selected either from ethnobotanical or chemotaxonomical data, were screened for their antiprotozoal activity against Leishmania donovani and Trypanosoma brucei brucei. The cytotoxic activity against KB cells was also determined.
M d R, Camacho, J D, Phillipson, S L, Croft, P N, Solis, S J, Marshall, S A, Ghazanfar   +5 more
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Antiprotozoal activity of the constituents of Rubus coriifolius

Phytotherapy Research, 2003
AbstractExtraction of the aerial parts of Rubus coriifolius, a medicinal plant used by the Maya communities in Southern Mexico to treat bloody diarrhoea, resulted in the isolation of seven known compounds (−)‐epicatechin, (+)‐catechin, hyperin, nigaichigoside F1, β‐sitosterol 3‐O‐β‐d‐glucopyranoside, gallic acid and ellagic acid.
Alma Delia, Alanís, Fernando, Calzada, Roberto, Cedillo-Rivera, Mariana, Meckes   +3 more
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Macrophage Activation: Enhanced Oxidative and Antiprotozoal Activity

1984
Although only one of the array of secretory properties displayed by activated macrophages, the capacity to generate increased amounts of reactive oxygen intermediates is a consistent biochemical marker of activation with clearly relevant biologic effects (Nathan et al., 1980).
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Natural Products with Antiprotozoal Activity

1999
Protozoal diseases are a major threat to the health of human populations and domestic animals worldwide, mainly due of the absence of vaccines and deficiencies in chemotherapy and vector control. Although chemotherapy has played a major role in the treatment and control of protozoal diseases since the pioneering work of Ehrlich at the beginning of the ...
S. L. Croft, C. R. Weiss
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In vitro antiprotozoal activity of the leaves of Artemisia ludoviciana

Fitoterapia, 2005
The inhabitants of Northeast of Mexico use an infusion of leaves from Artemisia ludoviciana as an antidiarrheal remedy. The aqueous, methanol, acetone and hexane leaf extracts from mature plants were found to be active in vitro against the parasitic protozoa Entamoeba histolytica and Giardia lamblia.
Salvador, Said Fernández, Monica Celina, Ramos Guerra, Benito David, Mata Cárdenas, Javier, Vargas Villarreal, Licet, Villarreal Treviño   +4 more
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Synthesis and in Vitro Antiprotozoal Activity of Bisbenzofuran Cations

Journal of Medicinal Chemistry, 2007
Forty three cationic bisbenzofurans were synthesized either by interaction of o-hydroxyaldehydes with alpha-halogenated ketones followed by intramolecular ring closure or by a copper- or palladium-mediated heteroannulation of substituted o-iodophenols with terminal acetylenes.
Svetlana M, Bakunova, Stanislav A, Bakunov, Tanja, Wenzler, Todd, Barszcz, Karl A, Werbovetz, Reto, Brun, James Edwin, Hall, Richard R, Tidwell   +7 more
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Absolute Configuration and Antiprotozoal Activity of Minquartynoic Acid

Journal of Natural Products, 2000
Minquartynoic acid (1) was isolated as an antimalarial and antileishmanial constituent of the Peruvian tree Minquartia guianensis and its absolute configuration at C-17 established to be (+)-S through conversion to the known (+)-(S)-17-hydroxystearic acid (2) and confirmed using Mosher's method.
Rasmussen, H B, Christensen, Søren Brøgger, Kvist, L P, Kharazmi, A, Huansi, A G   +4 more
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Antiprotozoal activity of the constituents of Teloxys graveolens

Phytotherapy Research, 2003
AbstractAntiprotozoal activity‐guided fractionation of a methanol extract of the aerial parts of Teloxys graveolens led to the isolation of one coumarinic acid derivative, melilotoside, and five flavonoids, pinocembrine, pinostrobin, chrysin, narcissin and rutin.
Fernando, Calzada, Claudia, Velázquez, Roberto, Cedillo-Rivera, Baldomero, Esquivel   +3 more
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Antiprotozoal and cytotoxic activities in vitro of Colombian Annonaceae

Journal of Ethnopharmacology, 2007
Ethnobotanical and chemotaxonomical studies for antiparasitic activity of Colombian Annonaceae were carried out. In vitro antiprotozoal activity of 36 extracts obtained from six different species was determined against promastigotes of three Leishmania species, epimastigotes of Trypanosoma cruzi and both chloroquine sensitive (F32) and resistant (W2 ...
Edison, Osorio, Gabriel Jaime, Arango, Nora, Jiménez, Fernando, Alzate, Grace, Ruiz, David, Gutiérrez, Marco Antonio, Paco, Alberto, Giménez, Sara, Robledo   +8 more
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