Results 1 to 10 of about 10,041 (160)

Bifurcatriol, a New Antiprotozoal Acyclic Diterpene from the Brown Alga Bifurcaria bifurcata

open access: yesMarine Drugs, 2017
Linear diterpenes that are commonly found in brown algae are of high chemotaxonomic and ecological importance. This study reports bifurcatriol (1), a new linear diterpene featuring two stereogenic centers isolated from the Irish brown alga Bifurcaria ...
Christian Merten   +2 more
exaly   +3 more sources

Antiprotozoal Effect of Snake Venoms and Their Fractions: A Systematic Review

open access: yesPathogens, 2021
Background: Protozoal infection is a lingering public health issue of great concern, despite efforts to produce drugs and vaccines against it. Recent breakthrough research has discovered alternative antiprotozoal agents encompassing the use of snake ...
Salihu Sabiu Musa   +2 more
exaly   +3 more sources

Peroxides with Anthelmintic, Antiprotozoal, Fungicidal and Antiviral Bioactivity: Properties, Synthesis and Reactions

open access: yesMolecules, 2017
The biological activity of organic peroxides is usually associated with the antimalarial properties of artemisinin and its derivatives. However, the analysis of published data indicates that organic peroxides exhibit a variety of biological activity ...
Alexander Terent'Ev   +2 more
exaly   +3 more sources

Antiprotozoal peptide prediction using machine learning with effective feature selection techniques [PDF]

open access: yesHeliyon
Background: Protozoal pathogens pose a considerable threat, leading to notable mortality rates and the ongoing challenge of developing resistance to drugs. This situation underscores the urgent need for alternative therapeutic approaches.
Neha Periwal   +8 more
doaj   +2 more sources

Novel Formula of Antiprotozoal Mixtures

open access: yesAntibiotics, 2022
Antimicrobial resistance (AMR) is becoming more common in both bacteria and pathogenic protozoa. Therefore, new solutions are being sought as alternatives to currently used agents.
Hubert Iwiński   +3 more
doaj   +1 more source

Pharmacological Assessment of the Antiprotozoal Activity, Cytotoxicity and Genotoxicity of Medicinal Plants Used in the Treatment of Malaria in the Greater Mpigi Region in Uganda

open access: yesFrontiers in Pharmacology, 2021
We investigated the potential antimalarial and toxicological effects of 16 medicinal plants frequently used by traditional healers to treat malaria, fever, and related disorders in the Greater Mpigi region in Uganda. Species studied were Albizia coriaria,
Fabien Schultz   +10 more
doaj   +1 more source

Antiparasitic Effects of Potentially Toxic Beetles (Tenebrionidae and Meloidae) from Steppe Zones

open access: yesToxins, 2021
Arthropods and specifically beetles can synthesize and/or sequester metabolites from dietary sources. In beetle families such as Tenebrionidae and Meloidae, a few studies have reported species with toxic defensive substances and antiparasitic properties ...
Marta Díaz-Navarro   +8 more
doaj   +1 more source

Analysis of Giardia lamblia Nucleolus as Drug Target: A Review

open access: yesPharmaceuticals, 2023
Giardia lamblia (G. lamblia) is the main causative agent of diarrhea worldwide, affecting children and adults alike; in the former, it can be lethal, and in the latter a strong cause of morbidity.
Carlos Gaona-López   +4 more
doaj   +1 more source

Antiprotozoal and Antitumor Activity of Natural Polycyclic Endoperoxides: Origin, Structures and Biological Activity

open access: yesMolecules, 2021
Polycyclic endoperoxides are rare natural metabolites found and isolated in plants, fungi, and marine invertebrates. The purpose of this review is a comparative analysis of the pharmacological potential of these natural products.
Valery M. Dembitsky   +4 more
doaj   +1 more source

Bioactive Essential Oils from Cuban Plants: An Inspiration to Drug Development

open access: yesPlants, 2021
Aromatic plants and essential oils are important agents as complementary and alternative medicines in many cultures and geographical locations. In this review, a literature search on essential oils from Cuba, their chemical compositions, and their ...
Lianet Monzote   +4 more
doaj   +1 more source

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