Results 31 to 40 of about 24,129 (266)
Molecules, 2012 Malaria, leishmaniasis and human African trypanosomiasis continue to be major public health problems in need of new and more effective drugs. The aim of this study was to evaluate in vitro antiprotozoal activity of twenty endemic medicinal plants ...
Louis Maes +4 more
doaj +1 more source
Antiprotozoal Nor-Triterpene Alkaloids from Buxus sempervirens L.
Antibiotics, 2021 Malaria and human African trypanosomiasis (HAT; sleeping sickness) are life-threatening tropical diseases caused by protozoan parasites. Due to limited therapeutic options, there is a compelling need for new antiprotozoal agents.
Lara U Szabó +3 more
semanticscholar +1 more source
Molecules, 2012 The present study investigated the <em>in vitro</em> antiprotozoal activity of sixteen selected medicinal plants. Plant materials were extracted with methanol and screened <em>in vitro</em> against erythrocytic schizonts of <em&
Nawal M. Al-Musayeib +5 more
doaj +1 more source
S100B inhibitor pentamidine attenuates reactive gliosis and reduces neuronal loss in a mouse model of Alzheimer's disease [PDF]
, 2015 Among the different signaling molecules released during reactive gliosis occurring in Alzheimer’s disease (AD), the astrocytederived S100B protein plays a key role in neuroinflammation, one of the hallmarks of the disease.
Capoccia, Elena +6 more
core +5 more sources
Antimicrobial Compounds from Skin Secretions of Species That Belong to the Bufonidae Family
Toxins, 2023 Skin secretions of toads are a complex mixture of molecules. The substances secreted comprise more than 80 different compounds that show diverse pharmacological activities.
Rodrigo Ibarra-Vega +7 more
doaj +1 more source
Angewandte Chemie, 2021 Leucinostatin A is one of the most potent antiprotozoal compounds ever described, but little was known on structure–activity relationships (SAR).
M. Brand +14 more
semanticscholar +1 more source
Anti-Trypanosoma cruzi action of a new benzofuran derivative based on amiodarone structure [PDF]
, 2018 Chagas disease is a neglected tropical affection caused by the protozoan parasite Trypanosoma cruzi. There is no current effective treatment since the only two available drugs have a limited efficacy and produce side effects.
Benaim, Gustavo +4 more
core +1 more source
Antiparasitic activity of chicory (Cichorium intybus) and its natural bioactive compounds in livestock: a review [PDF]
, 2018 Increasing drug resistance in gastrointestinal (GI) parasites of livestock and concerns about chemical residues in animal products and the environment are driving the development of alternative control strategies that are less reliant on the use of ...
Boas, Ulrik +7 more
core +4 more sources
BMC Complementary Medicine and Therapies, 2020 The antiprotozoal and antioxidant activities of Viola tricolor and Laurus nobilis have been reported recently. Thus, the existing study pursued to assess the growth inhibition effect of methanolic extract of V.
G. Batiha +7 more
semanticscholar +1 more source
Diversity, 2021 Since the long-term application of synthetic chemicals as insecticides and the chemotherapy of protozoal diseases have had various negative effects (non-target effects, resistance), research on less harmful biological products is underway. This review is
Arthur M. Muhoro, Edit É. Farkas
doaj +1 more source