Results 1 to 10 of about 5,425 (117)
Anthraquinones with Antiplasmodial Activity from the Roots of Rennellia elliptica Korth. (Rubiaceae)
Molecules, 2010 Dichloromethane root extract of Rennellia elliptica Korth. showed strong inhibition of Plasmodium falciparum growth in vitro with an IC50 value of 4.04 µg/mL.
Khalijah Awang +2 more
exaly +3 more sources
Antiplasmodial Natural Products
Molecules, 2011 Malaria is a human infectious disease that is caused by four species of Plasmodium. It is responsible for more than 1 million deaths per year. Natural products contain a great variety of chemical structures and have been screened for antiplasmodial ...
Lucia Lopes, Claudio Nogueira
exaly +3 more sources
Molecules, 2013 Malaria and leishmaniasis are two of the World’s most important tropical parasitic diseases. Continuing with our efforts to identify new compounds active against malaria and leishmaniasis, twelve new 1,4-di-N-oxide quinoxaline derivatives were ...
Germ´An Gonzalez Aspajo +2 more
exaly +3 more sources
Plants, 2022 Cryptolepis sanguinolenta (Lindl.) Schlt., the main source of cryptolepine alkaloid, is intensively exploited in the wild to treat malaria and Lyme disease.
Jacqueline Naalamle Amissah +6 more
doaj +1 more source
Antiplasmodial Compounds from Deep-Water Marine Invertebrates
Marine Drugs, 2021 Novel drug leads for malaria therapy are urgently needed because of the widespread emergence of resistance to all available drugs. Screening of the Harbor Branch enriched fraction library against the Plasmodium falciparum chloroquine-resistant strain ...
Amy E. Wright +8 more
doaj +1 more source
Antiplasmodial and Cytotoxic Flavonoids from Pappea capensis (Eckl. & Zeyh.) Leaves
Molecules, 2021 Ethnobotanical surveys indicate that the Masai and Kikuyu in Kenya, the Venda in South Africa, and the Gumuz people of Ethiopia use Pappea capensis for the treatment of malaria.
Nasir Tajuddeen +3 more
doaj +1 more source
In Vitro Antiplasmodial, Heme Polymerization, and Cytotoxicity of Hydroxyxanthone Derivatives
Journal of Tropical Medicine, 2021 The previous study showed that xanthone had antiplasmodial activity. Xanthone, with additional hydroxyl groups, was synthesized to increase its antiplasmodial activity.
Mistika Zakiah +5 more
doaj +1 more source
Biology, Medicine & Natural Product Chemistry, 2022 Antimalarial drug resistance is one of the greatest challenges towards eradicating malaria. Exploring new combination therapies can overcome resistance challenges.
Udeme Owunari Georgewill, Elias Adikwu
doaj +1 more source
Antiplasmodial Activity of The Low Molecular Weight Compounds from Streptomyces sp. GMR22
Indonesian Journal of Pharmacy, 2020 Low molecular weight (LMW) antiplasmodial compounds isolated from bacteria, particularly Streptomyces have not been widely reported. This study aimed to identify LMW compounds from Streptomyces sp. GMR22 as antiplasmodial.
Tarsa Ruli Tambunan +4 more
doaj +1 more source
Frontiers in Pharmacology, 2023 Background: Medicinal plants have traditionally been used as remedies against malaria. The present review attempted to compile data on scientific research evidence on antimalarial medicinal plants screened at Kenya Medical Research Institute (KEMRI ...
Beatrice Irungu +4 more
doaj +1 more source