Results 21 to 30 of about 5,494 (181)

Gas chromatography–mass spectrometry characterization of bioactive compounds from Ziziphus nummularia (Burm. F.) stem bark with promising in vitro antiplasmodial activity

open access: yesJournal of Pharmacy and Bioallied Sciences, 2020
Objective: This study was carried out to evaluate the in vitro antiplasmodial activity of alcoholic and hydroalcoholic extract of Ziziphus nummularia stem bark as well as the determination of core structure fractionated from its crude extract.
Babita Aggarwal   +2 more
doaj   +1 more source

Unveiling antiplasmodial alkaloids from a cumulative collection of Strychnos extracts by multi-informative molecular networks

open access: yesFrontiers in Molecular Biosciences, 2022
Malaria, a disease known for thousands of years and caused by parasites of the Plasmodium genus, continues to cause many deaths throughout the world today, particularly due to the emergence of parasite resistance to the current therapeutic arsenal ...
Olivier Bonnet   +10 more
doaj   +1 more source

Chemical Composition of Aspidosperma ulei Markgr. and Antiplasmodial Activity of Selected Indole Alkaloids

open access: yesMolecules, 2013
A new indole alkaloid, 12-hydroxy-N-acetyl-21(N)-dehydroplumeran-18-oic acid (13), and 11 known indole alkaloids: 3,4,5,6-tetradehydro-β-yohimbine (3), 19(E)-hunteracine (4), b-yohimbine (5), yohimbine (6), 19,20-dehydro-17-a-yohimbine (7), uleine (10 ...
Adrian Martin Pohlit   +7 more
doaj   +1 more source

In Vitro Assessment of Antiplasmodial and Antitrypanosomal Activities of Chloroform, Ethyl Acetate and Ethanol Leaf Extracts of Oedera genistifolia

open access: yesApplied Sciences, 2020
The high resistance evolution of protozoans to the existing antiparasitic drugs has necessitated the quest for novel and effective drugs against plasmodium and trypanosome parasites.
Kunle Okaiyeto, Anthony I. Okoh
doaj   +1 more source

Phytochemical and Antiplasmodial Evaluation of Five Colombian Plants with Ethnopharmacological Background of Antimalarial Use [PDF]

open access: yesPharmaceutical Sciences, 2023
Background: The study of medicinal plants has made it possible to develop products and drugs for the treatment of different diseases. Several plants in Colombia have a history of popular use for the treatment of malaria. The objective of this work was to
Jorge Enrique Hernández-Carvajal   +5 more
doaj   +1 more source

4-Arylthieno[2,3-b]pyridine-2-carboxamides Are a New Class of Antiplasmodial Agents

open access: yesMolecules, 2020
Malaria causes hundreds of thousands of deaths every year, making it one of the most dangerous infectious diseases worldwide. Because the pathogens have developed resistance against most of the established anti-malarial drugs, new antiplasmodial agents ...
Sandra I. Schweda   +3 more
doaj   +1 more source

Configuration and Antiplasmodial Activity [PDF]

open access: yesNature, 1944
THE current view1,2 that there is no relationship between optical activity (configuration) and antiplasmodial action in the Cinchona series does not appear to be fully justified.
openaire   +1 more source

Alcaloides isoquinolínicos e investigação das atividades antiplasmódica e antibacteriana de Guatteria citriodora (Annonaceae)

open access: yesQuímica Nova, 2014
Phytochemical investigations of the stem bark, leaves and twigs of Guatteria citriodora resulted in the isolation of eight alkaloids: liriodenine, lysicamine, O-methylmoschatoline, 3-methoxyoxoputerine, palmatine, 3-methoxyguadiscidine, guattescidine and
Diego de M. Rabelo   +7 more
doaj   +1 more source

Machine learning enhances prediction of plants as potential sources of antimalarials

open access: yesFrontiers in Plant Science, 2023
Plants are a rich source of bioactive compounds and a number of plant-derived antiplasmodial compounds have been developed into pharmaceutical drugs for the prevention and treatment of malaria, a major public health challenge. However, identifying plants
Adam Richard-Bollans   +23 more
doaj   +1 more source

Synthesis, characterization, antimalarial, antitrypanocidal and antimicrobial properties of gold nanoparticle

open access: yesGreen Chemistry Letters and Reviews, 2019
In this study, we report on the biosynthesis of gold nanoparticles (AuNPs) by using Callistemon citrinus (C. citrinus) seed extract as both reducing and capping agent as well as its characterization.
Larayetan Rotimi   +4 more
doaj   +1 more source

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