Results 11 to 20 of about 24,129 (266)

Coinfection of Leishmania (Viannia) braziliensis and Streptococcus pneumoniae in multiple cutaneous lesions [PDF]

, 2016
Key learning points Cutaneous leishmaniasis is the most common clinical disease caused by all the Leishmania species that are pathogenic to humans. Other bacterial coinfections of Leishmania lesions have been described, but this is the first report of ...
Chiapello, Laura Silvina, Cortes, Paulo R., De Petris, Carlos, Dib, David, Echenique, Jose Ricardo, Herrero, Mónica V., Nuncira, Carmen T.   +6 more
core   +10 more sources

An Overview of the Synthesis and Antimicrobial, Antiprotozoal, and Antitumor Activity of Thiazole and Bisthiazole Derivatives

Molecules, 2021
Thiazole, a five-membered heteroaromatic ring, is an important scaffold of a large number of synthetic compounds. Its diverse pharmacological activity is reflected in many clinically approved thiazole-containing molecules, with an extensive range of ...
Anca-Maria Borcea, Ioana Ionuț, O. Crișan, O. Oniga   +3 more
semanticscholar   +1 more source

Pharmacological Assessment of the Antiprotozoal Activity, Cytotoxicity and Genotoxicity of Medicinal Plants Used in the Treatment of Malaria in the Greater Mpigi Region in Uganda

Frontiers in Pharmacology, 2021
We investigated the potential antimalarial and toxicological effects of 16 medicinal plants frequently used by traditional healers to treat malaria, fever, and related disorders in the Greater Mpigi region in Uganda. Species studied were Albizia coriaria,
Fabien Schultz, Fabien Schultz, Ogechi Favour Osuji, Anh Nguyen, Godwin Anywar, John R. Scheel, John R. Scheel, Guy Caljon, Luc Pieters, Leif-Alexander Garbe, Leif-Alexander Garbe   +10 more
doaj   +1 more source

Phytochemical and Biological Evaluation of Leaves, Stems, and Roots of Schinus weinmanniifolia Mart. Ex Engl. [PDF]

Chem Biodivers
Ethanolic extracts from leaves, stems, and roots of Schinus weinmanniifolia Mart. ex Engl. were evaluated for phytochemical composition and biological activities. The extracts exhibited antioxidant, photoprotective, and antimicrobial activity, without hemolytic effects or cytotoxicity at active concentrations. Syringic acid, epicatechin, and rutin were
Andrade J, de Almeida-Apolonio AA, Dantas FGDS, Santos JIDS, Sangalli A, Negri M, Ferreira DG, Cardoso CAL, de Castro TLA, Gomes ADSG, Bonono R, Fernandes L, Rodrigues ME, Henriques MCR, de Oliveira KMP.   +14 more
europepmc   +2 more sources

Antiparasitic Effects of Potentially Toxic Beetles (Tenebrionidae and Meloidae) from Steppe Zones

Toxins, 2021
Arthropods and specifically beetles can synthesize and/or sequester metabolites from dietary sources. In beetle families such as Tenebrionidae and Meloidae, a few studies have reported species with toxic defensive substances and antiparasitic properties ...
Marta Díaz-Navarro, Paula Bolívar, María Fe Andrés, María Teresa Gómez-Muñoz, Rafael A. Martínez-Díaz, Félix Valcárcel, Mario García-París, Luis M. Bautista, Azucena González-Coloma   +8 more
doaj   +1 more source

Antiprotozoal drugs: challenges and opportunities

Expert Opinion on Therapeutic Patents, 2023
Protozoans are widespread organisms in most habitats worldwide, being a paraphyletic group with an intricate evolutionary history [1,2]. There is a multitude of phyla, genera, and protozoan species, many of which ecologically and industrially relevant ...
C. Supuran
semanticscholar   +1 more source

Analysis of Giardia lamblia Nucleolus as Drug Target: A Review

Pharmaceuticals, 2023
Giardia lamblia (G. lamblia) is the main causative agent of diarrhea worldwide, affecting children and adults alike; in the former, it can be lethal, and in the latter a strong cause of morbidity.
Carlos Gaona-López, Ana Verónica Martínez-Vázquez, Juan Carlos Villalobos-Rocha, Karina Janett Juárez-Rendón, Gildardo Rivera   +4 more
doaj   +1 more source

Bioactive Essential Oils from Cuban Plants: An Inspiration to Drug Development

Plants, 2021
Aromatic plants and essential oils are important agents as complementary and alternative medicines in many cultures and geographical locations. In this review, a literature search on essential oils from Cuba, their chemical compositions, and their ...
Lianet Monzote, Jesús García, Rosalia González, Marcus Tullius Scotti, William N. Setzer   +4 more
doaj   +1 more source

Thio- and selenosemicarbazones as antiprotozoal agents against Trypanosoma cruzi and Trichomonas vaginalis

Journal of Enzyme Inhibition and Medicinal Chemistry, 2022
Herein, we report the preparation of a panel of Schiff bases analogues as antiprotozoal agents by modification of the stereoelectronic effects of the substituents on N-1 and N-4 and the nature of the chalcogen atom (S, Se). These compounds were evaluated
Alexandra Ibáñez-Escribano, Cristina Fonseca-Berzal, Mónica Martínez-Montiel, M. Álvarez-Márquez, María Gómez-Núñez, Manuel Lacueva-Arnedo, Teresa Espinosa-Buitrago, Tania Martín-Pérez, J. Escario, Penélope Merino‐Montiel, S. Montiel-Smith, A. Gómez-Barrio, Ó. López, J. Fernández-Bolaños   +13 more
semanticscholar   +1 more source

Hura crepitans Seeds for Control of Eimeria spp. in Lambs as an Alternative to Conventional Therapies

Veterinary Sciences, 2022
To evaluate the anticoccidial effect of the Hura crepitans seed, 21 cross-breed lambs, 23 ± 3 kg live weight (PV) and 70 ± 6 days old, were used. Animals were housed individually in raised wire-mesh pens, with individual water troughs and feeders.
Martha-Yanira Velazquez-González, Jose-Lenin Loya-Olguin, Yissel-Sacnicte Valdes-Garcia, Sergio Martinez-Gonzalez, Fidel Avila-Ramos, Francisco Escalera-Valente, Jose-Ramiro Gonzalez-Montaña   +6 more
doaj   +1 more source