Results 111 to 120 of about 6,609 (178)

S100B‐p53 disengagement by pentamidine promotes apoptosis and inhibits cellular migration via aquaporin‐4 and metalloproteinase‐2 inhibition in C6 glioma cells

, 2015
S100 calcium‐binding protein B (S100B) is highly expressed in glioma cells and promotes cancer cell survival via inhibition of the p53 protein. In melanoma cells, this S100B‐p53 interaction is known to be inhibited by pentamidine isethionate, an ...
CAPOCCIA E, CIRILLO C, CUOMO, ROSARIO, D'ALESSANDRO, ALESSANDRA, ESPOSITO G., MARCHETTO A, PESCE, MARCELLA, SARNELLI, GIOVANNI, SAWIKR Y, SCUDERI C, STEARDO L, TIBERI S   +11 more
core   +1 more source

An impact of the combined drug containing antimicrobial, antiprotozoal, antifungal and glucocorticoid agents on local immunity in women with bacterial vaginosis and non-specific vaginitis

, 2021
O. M. Bokach, M. S. Murasheva, M. S. Selkova, Kseniia V. Storozheva, S. V. Chepanov, S. А. Selkov   +5 more
openalex   +2 more sources

Trypanocidal potentials of Jatropha curcas L. 1753 leaf extracts and fractions in vivo

Pharmacological Research - Modern Chinese Medicine
Introduction: Trypanosomiasis is a debilitating parasitic disease affecting both humans and animals, leading to substantial economic losses in the livestock sector due to reduced productivity and increased mortality.
Haolat Yusuf, Abdulhakeem Binhambali, Mutiu Olawale Rahmon, Ridwan Bolaji Yusuf, Suleiman Garba Salihu, Barnabas Jarumi Musa   +5 more
doaj   +1 more source

Editorial: Cutaneous Leishmaniasis: Exploring Pathogenesis and Immunomodulatory Approaches

Frontiers in Cellular and Infection Microbiology, 2022
Wander Rogério Pavanelli, Izabel Galhardo Demarchi   +1 more
doaj   +1 more source

Modulation of the Mechanism of Action of the 2-Arylquinazoline Through Functionalization at 4-Position: A Strategy to Access to a Potent Antiprotozoal Agent

, 2023
Angel H. Romero, Elena Paola AGUILERA LÓPEZ, Lourdes Gotopo, Gustavo Cabrera, Belén Dávila, Hugo Cerecetto Meyer   +5 more
openalex   +1 more source

A Divergent Synthesis of Numerous Pyrroloiminoquinone Alkaloids Identifies Promising Antiprotozoal Agents [PDF]

Griffin L. Barnes, Nicholas L. Magann, Daniele Perrotta, Fabian M. Hörmann, Sebastian Fernandez, Pratap Vydyam, Jae‐Yeon Choi, Jacques Prudhomme, Armund Neal, Karine G. Le Roch, Choukri Ben Mamoun, Christopher D. Vanderwal   +11 more
openalex   +3 more sources

Correction to: Coumarins as Potential Antiprotozoal Agents: Biological Activities and Mechanism of Action [PDF]

, 2021
Elkin José Torres Sierra, Cleydson Finotti Cordeiro, Lívia de Figueiredo Diniz, Ivo Santana Caldas, Jamie Anthony Hawkes, Diogo Teixeira Carvalho   +5 more
openalex   +1 more source

Kallopterolides A–I, a New Subclass of seco-Diterpenes Isolated from the Southwestern Caribbean Sea Plume Antillogorgia kallos

Molecules
Kallopterolides A–I (1–9), a family of nine diterpenoids possessing either a cleaved pseudopterane or a severed cembrane skeleton, along with several known compounds were isolated from the Caribbean Sea plume Antillogorgia kallos.
Jeffrey Marrero, Luis A. Amador, Ivan M. Novitskiy, Andrei G. Kutateladze, Abimael D. Rodríguez   +4 more
doaj   +1 more source

Hydrazinated geraniol derivatives as potential broad‐spectrum antiprotozoal agents [PDF]

Joelien Jooste, Lesetja J. Legoabe, Kayhan Ilbeigi, Guy Caljon, Richard M. Beteck   +4 more
openalex   +1 more source

Target-Based 6-5 Fused Ring Heterocyclic Scaffolds Display Broad Antiparasitic Potency In Vitro

Future Pharmacology
Malaria, leishmaniasis, and African trypanosomiasis are protozoan diseases that constitute major global health problems, especially in developing countries; however, the development of drug resistance coupled with the toxicity of current treatments has ...
Darline Dize, Mariscal Brice Tchatat Tali, Cyrille Armel Njanpa Ngansop, Rodrigue Keumoe, Eugenie Aimée Madiesse Kemgne, Lauve Rachel Tchokouaha Yamthe, Patrick Valere Tsouh Fokou, Boniface Pone Kamdem, Katsura Hata, Fabrice Fekam Boyom   +9 more
doaj   +1 more source