Antileishmanial potential of medicinal plants: A global systematic and meta-analytic review of in vitro studies [PDF]
Journal of HerbMed PharmacologyIntroduction: Leishmaniasis is a major global health challenge with limited treatment options and rising drug resistance. Medicinal plants, traditionally used in many regions, offer a promising source of new antileishmanial agents.
Mohammed-Yassine Takzima +4 more
doaj +1 more source
Cu(II) and Fe(III) complexes of sulphadoxine mixed with pyramethamine: Synthesis, characterization, antimicrobial and toxicology study [PDF]
, 2012 Two new mixed ligands metal complexes of sulphadoxine and pyramethamine were prepared by using CuCl2.6H2O and FeCl3.6H2O. The complexes were characterized by elemental analysis, melting point determination, molar conductivity, metal content analysis (AAS)
Adekoya, J. A. +5 more
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Room Temperature Synthesis and Antibacterial Activity of New Sulfonamides Containing N,N -Diethyl-Substituted AmidoMoieties [PDF]
, 2012 Sulfonamide drugs which have brought about an antibiotic revolution in medicine are associated with a wide range of biological activities.
Ajani, Olayinka O. +4 more
core +5 more sources
BioMed Research International, Volume 2026, Issue 1, 2026.Introduction Cancer is a versatile disease with a high rate of relapse and mortality. Despite the presence of various treatment modalities, there is a serious need for the development of its management. Phytochemicals, which are abundant in nature, can be turned into novel medications for these types of diseases by optimizing their functions and ...
Mithila Kulkarni +5 more
wiley +1 more source
Guidelines for the treatment of bacterial vaginosis: focus on tinidazole [PDF]
, 2009 Laura J Dickey1, Michael D Nailor2,3, Jack D Sobel41Department of Pharmacy Services, Detroit Receiving Hospital, Detroit, MI, USA; 2University of Connecticut, School of Pharmacy, Storrs, CT, USA; 3Hartford Hospital, Department of Pharmacy, Hartford, CT ...
Laura J Dickey +2 more
core +1 more source
Quantitative structure-activity relationship of some 1-benzylbenzimidazole derivatives as antifungal agents [PDF]
, 2007 In the present study, the antifungal activity of some 1-benzylbenzimidazole derivatives against yeast Saccharomyces cerevisiae was investigated. The tested benzimidazoles displayed in vitro antifungal activity and minimum inhibitory concentration (MIC ...
Barna Dijana J. +2 more
core +1 more source
The Role of Natural Products in Drug Discovery and Development against Neglected Tropical Diseases
Molecules, 2016 Endemic in 149 tropical and subtropical countries, neglected tropical diseases (NTDs) affect more than 1 billion people annually, including 875 million children in developing economies. These diseases are also responsible for over 500,000 deaths per year
Peter Mubanga Cheuka +3 more
doaj +1 more source
Microbial Population and Fermentation Characteristic in Response to Sapindus Rarak Mineral Block Supplementation [PDF]
, 2010 This experiment was conducted to evaluate the effect of supplementation with lerak extract combined with mineral block on protozoal and bacterial population, and fermentation characteristic in vitro.
Astuti, D. A. (D) +3 more
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Bisguanidine, Bis(2-aminoimidazoline), and Polyamine Derivatives as Potent and Selective Chemotherapeutic Agents against Trypanosoma brucei rhodesiense. Synthesis and in Vitro Evaluation [PDF]
, 2013 The in vitro screening for trypanocidal activity against Trypanosoma brucei rhodesiense of an in-house library of 62 compounds [i.e. alkane, diphenyl, and azaalkane bisguanidines and bis-(2-aminoimidazolines)], which were chosen for their structural ...
Brun, Reto, Dardonville, Christophe
core +2 more sources
MoleculesTrypanosoma cruzi is a protozoan parasite that causes Chagas disease in humans. The current antichagasic drugs nifurtimox and benznidazole have inconveniences of toxicity; therefore, the search for alternative therapeutic strategies is necessary.
Citlali Vázquez +7 more
doaj +1 more source