Results 71 to 80 of about 5,274,206 (218)

Antiviral Activity of Approved Antibacterial, Antifungal, Antiprotozoal and Anthelmintic Drugs: Chances for Drug Repurposing for Antiviral Drug Discovery

Journal of Experimental Pharmacology, 2022
Leena Abdulaziz,1 Esraa Elhadi,1,2 Ejlal A Abdallah,3 Fadlalbaseer A Alnoor,4 Bashir A Yousef5 1Department of Pharmacology, Faculty of Pharmacy, Omdurman Islamic University, Khartoum, 14415, Sudan; 2Jiangsu Key Laboratory of Drug Screening, China ...
Abdulaziz L, Elhadi E, Abdallah EA, Alnoor FA, Yousef BA   +4 more
doaj  

Some nitroimidazole derivatives as antibacterial and antifungal agents in in vitro study

Journal of Medical Science, 2019
Nitroimidazoles have wide range of therapeutic uses mainly as anaerobic antibacterials and antiprotozoal agents. Some bicyclic nitroimidazodihydrooxazoles and nitroimidazotetrahydrooxazines are found to be antituberculosis agents.
Justyna Żwawiak, Dorota Olender, Lucjusz Zaprutko   +2 more
doaj   +1 more source

Design, Synthesis, and Biological Evaluation of New 1-(Aryl-1 H-pyrrolyl)(phenyl)methyl-1 H-imidazole Derivatives as Antiprotozoal Agents.

Journal of Medicinal Chemistry, 2019
We have designed and synthesized a series of new imidazole-based compounds structurally related to an antiprotozoal agent with nanomolar activity which we identified recently.
Francesco Saccoliti, V. N. Madia, Valeria Tudino, Alessandro De Leo, L. Pescatori, A. Messore, D. de Vita, L. Scipione, R. Brun, M. Kaiser, P. Mäser, C. M. Calvet, Gareth Jennings, L. Podust, G. Pepe, R. Cirilli, C. Faggi, A. DiMarco, Maria Rosaria Battista, V. Summa, R. Costi, R. Di Santo   +21 more
semanticscholar   +1 more source

Clinical and Diagnostic Considerations in Laryngeal Leishmaniasis: A Systematic Review

OTO Open, Volume 10, Issue 3, July-September 2026.
Abstract Objective Laryngeal leishmaniasis is a rare, insidious manifestation of Leishmania infection with potential for life‐threatening complications. Awareness is critical for efficient and timely diagnosis. This systematic review of laryngeal leishmaniasis focuses on presentation, treatment, and the role of serological studies in the work up of ...
Joseph Celidonio, Nicholas Hamilton, Alexandra Filipkowski, Raj Malhotra, Samantha Shave, Myat E. Mon, Kenneth Yan, Rachel Kaye   +7 more
wiley   +1 more source

Analogs of 5-methylthioribose, a novel class of antiprotozoal agents [PDF]

Antimicrobial Agents and Chemotherapy, 1988
Since drug resistance and toxicity limit the use of available antiprotozoal agents, it is important that new drugs be developed as soon as possible. In this study, the method by which several protozoa degrade 5'-methylthioadenosine (MTA) was shown to differ from MTA catabolism in human cells.
M K, Riscoe, A J, Ferro, J H, Fitchen
openaire   +2 more sources

Flavonoids in Nasal Therapeutics: Biological Activities, Delivery Challenges, and Formulation Strategies–A Systematic Review

Phytotherapy Research, Volume 40, Issue 7, Page 4676-4709, July 2026.
Overview of the therapeutic potential of flavonoids in nasal delivery systems, highlighting their benefits to the human nasal cavity, and applications in the treatment of respiratory and brain‐related diseases. ABSTRACT Flavonoids represent a significant group of secondary metabolites.
Jeniffer Viviana Ramirez Hernández, Sara Elis Bianchi, Flávia Nathiely Silveira Fachel, Elizandra Braganhol, Sheila Porto de Matos, Valquíria Linck Bassani   +5 more
wiley   +1 more source

Discovery of natural antiprotozoals from medicinal plants Saussurea costus and Carica papaya [PDF]

, 2014
Medicinal plants have been an important source for the discovery of therapeutic agents for infectious diseases. In order to explore their potential an appropriate selection of plant species is important.
Julianti, Tasqiah
core   +1 more source

Quinolines: the role of substitution site in antileishmanial activity

Frontiers in Chemistry
Leishmaniasis is one of the most widespread parasitic diseases in the world, primarily affecting the poorest and most vulnerable populations. The development of new therapeutic agents that are more efficient, safe, and selective remains a challenge.
Orlando G. Elso, Guadalupe García Liñares   +1 more
doaj   +1 more source

Evaluation of the Utilization Pattern of Veterinary Drugs in Selected Veterinary Clinics of Mekelle City, Tigray, Ethiopia

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
Veterinary drug utilization patterns were assessed in three veterinary clinics in Mekelle City, Ethiopia. Antimicrobials, particularly oxytetracycline, constitute the majority of prescriptions, followed by anthelmintics. Drug prescribing frequently relies on tentative diagnosis rather than evidence‐based diagnostic procedures.
Helen Hagos, Mebrahtu Weldegebriel, Hagazi Fantay, Haftom Yirga Tsegay   +3 more
wiley   +1 more source

Synthesis of Possible Antiprotozoal Agents

, 1984
Department of Chemical Technology, University College of Science, 92, Acharya P. C. Road, Calcutta-700 009 Manuscript received 3 December 1982, revised 30 November 1983, accepted 26 May 1984 Synthesis of Possible Antiprotozoal ...
B. R. SARKAR, D. GHOSH, B. C. PATHAK
openaire   +2 more sources