Results 51 to 60 of about 5,274,206 (218)
Symmetrical and unsymmetrical α,ω-nucleobase amide-conjugated systems
Beilstein Journal of Organic Chemistry, 2010 We present the synthesis and selected physicochemical properties of several novel symmetrical and unsymmetrical α,ω-nucleobase mono- and bis-amide conjugated systems containing aliphatic, aromatic or saccharidic linkages. The final stage of the synthesis
Sławomir Boncel +4 more
doaj +1 more source
Medicinal and Crop Protection Chemistry: Breaking Barriers, Building Synergies
ChemMedChem, Volume 21, Issue 16, 27 August 2026.A unified view of medicinal and crop protection chemistry reveals shared scientific progress, common challenges, and new opportunities for cross‐disciplinary collaboration. Bridging expertise across both fields could accelerate innovation and actively encourage more sustainable solutions.
Giulia Cazzaniga +5 more
wiley +1 more source
Synthesis and Antiprotozoal Profile of 3,4,5‐Trisubstituted Isoxazoles
ChemistryOpen, 2021 A series of 60 4‐aminomethyl 5‐aryl‐3‐substituted isoxazoles were synthesized by an efficient method and evaluated in vitro against Leishmania amazonensis and Trypanosoma cruzi, protozoa that cause the neglected tropical diseases leishmaniasis and Chagas
Prof. Fernanda Andreia Rosa +9 more
doaj +1 more source
Animal Research and One Health, Volume 4, Issue 3, Page 302-313, August 2026.Activo Liquid and Halquinol inhibit Salmonella and Escherichia coli in culture media. Activo Liquid exhibits bactericidal action, whereas HA is bacteriostatic, and their combination results in positive or indifferent interactions. This combination effectively inhibits E. coli throughout digestion simulation, thus reducing the required concentrations of
Alberto Gonçalves Evangelista +6 more
wiley +1 more source
Antiprotozoal Activity of Essential Oils [PDF]
, 2012 In the present scenario of protozoal infections, new drugs are urgently needed to treat and control infections such as malaria, sleeping sickness, Chagas disease, leishmaniasis and intestinal infections, which affect millions of people each year. In this
Alarcón, Oswald +2 more
core +1 more source
British Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2937-2948, August 2026.Background Reporting adverse drug reactions (ADRs) is essential for drug safety. In Switzerland, healthcare professionals are legally required to report serious and unlabelled ADRs, yet under‐reporting remains widespread. We tested a novel method to increase reporting of ADR‐related hospitalizations.
Georgia Anita Weber +7 more
wiley +1 more source
Determination of antiprotozoal drug mechanisms by metabolomics approaches [PDF]
, 2014 The discovery, development and optimal utilization of pharmaceuticals can be greatly enhanced by knowledge of their modes of action. However, many drugs currently on the market act by unknown mechanisms.
Creek, DJ +3 more
core +1 more source
Design and syntheses of 4-aminoquinoline-thiazolidinone hybrids as anti-protozoal agents
Frontiers in ChemistryIntroductionMolecular hybridization is an effective approach employed to synthesize molecules that possess the ability to function as dual inhibitors, thereby addressing the issue of growing resistance.
Gul Naz Fatima +2 more
doaj +1 more source
Novel hydroxynaphthalene and quinoline derivatives effective against Trypanosoma and Leishmania
ADMET and DMPKBackground and purpose: The increasing prevalence of multidrug-resistant parasites, particularly Trypanosoma and Leishmania, together with the limited efficacy of current therapies, highlights the need for new antiprotozoal agents.
Tomas Gonec +17 more
doaj +1 more source
Identification of Antiprotozoal Compounds from Buxus sempervirens L. by PLS-Prediction
Molecules, 2021 Various nor-triterpene alkaloids of Buxus (B.) sempervirens L. have shown remarkable in vitro activity against the causative agents of tropical malaria and East African sleeping sickness.
Lara U. Szabó +3 more
doaj +1 more source