Results 41 to 50 of about 8,093 (191)
Symmetrical and unsymmetrical α,ω-nucleobase amide-conjugated systems
Beilstein Journal of Organic Chemistry, 2010 We present the synthesis and selected physicochemical properties of several novel symmetrical and unsymmetrical α,ω-nucleobase mono- and bis-amide conjugated systems containing aliphatic, aromatic or saccharidic linkages. The final stage of the synthesis
Sławomir Boncel +4 more
doaj +1 more source
Furanocoumarins from Ruta chalepensis with Amebicide Activity
Molecules, 2021 Entamoeba histolytica (protozoan; family Endomoebidae) is the cause of amoebiasis, a disease related to high morbidity and mortality. Nowadays, this illness is considered a significant public health issue in developing countries.
Aldo Fabio Bazaldúa-Rodríguez +5 more
doaj +1 more source
British Journal of Clinical Pharmacology, EarlyView.Background Reporting adverse drug reactions (ADRs) is essential for drug safety. In Switzerland, healthcare professionals are legally required to report serious and unlabelled ADRs, yet under‐reporting remains widespread. We tested a novel method to increase reporting of ADR‐related hospitalizations.
Georgia Anita Weber +7 more
wiley +1 more source
European Journal of Organic Chemistry, EarlyView.Straightforward access to oxazole‐containing piperidines through a multicomponent reaction from α‐isocyanoacetates is described. By expanding the reactivity of these a‐isocyanoacetates from aldehydes to ketones, this process efficiently delivers oxazolyl‐piperidines bearing a quaternary stereocenter as valuable scaffolds relevant to drug discovery. The
Roshan Chandrakant Kajare +3 more
wiley +1 more source
Phytotherapy Research, EarlyView.Overview of the therapeutic potential of flavonoids in nasal delivery systems, highlighting their benefits to the human nasal cavity, and applications in the treatment of respiratory and brain‐related diseases. ABSTRACT Flavonoids represent a significant group of secondary metabolites.
Jeniffer Viviana Ramirez Hernández +5 more
wiley +1 more source
Synthesis and Antiprotozoal Profile of 3,4,5‐Trisubstituted Isoxazoles
ChemistryOpen, 2021 A series of 60 4‐aminomethyl 5‐aryl‐3‐substituted isoxazoles were synthesized by an efficient method and evaluated in vitro against Leishmania amazonensis and Trypanosoma cruzi, protozoa that cause the neglected tropical diseases leishmaniasis and Chagas
Prof. Fernanda Andreia Rosa +9 more
doaj +1 more source
Veterinary Ophthalmology, Volume 28, Issue 2, Page 438-447, March 2025.Abstract Objective This retrospective study evaluates the efficacy of povidone‐iodine (PI) and polyhexamethylene biguanide (PHMB) as preoperative antiseptics in equine ophthalmic procedures. Animals Studied Horses that underwent routine ophthalmic surgery and procedures.
Anna Farkas +4 more
wiley +1 more source
Applied Organometallic Chemistry, Volume 40, Issue 7, July 2026.1,2‐Disubstituted ferrocene analogues bearing hydantoin or rhodanine synthons were synthesised and assessed for antitrypanosomatid activity. An antileishmanial early lead, analogue 23, acting through ROS generation and hence oxidative stress, was uncovered.
Maryna Saayman +7 more
wiley +1 more source
Pathogens, 2019 The incidence of neglected diseases in tropical countries, such as Leishmaniasis and Chagas’s disease, is attributed to a set of biological and ecological factors associated with the socioeconomic context of developing countries and with a ...
Eliana B. Souto +8 more
doaj +1 more source
Identification of Antiprotozoal Compounds from Buxus sempervirens L. by PLS-Prediction
Molecules, 2021 Various nor-triterpene alkaloids of Buxus (B.) sempervirens L. have shown remarkable in vitro activity against the causative agents of tropical malaria and East African sleeping sickness.
Lara U. Szabó +3 more
doaj +1 more source