Results 41 to 50 of about 7,929 (164)

Synthesis, Electrochemistry, In Vitro Antiprotozoal Efficacy and Mechanistic Study of Novel ‘Ferrantoin’ and Related Derivatives

Applied Organometallic Chemistry, Volume 40, Issue 7, July 2026.
1,2‐Disubstituted ferrocene analogues bearing hydantoin or rhodanine synthons were synthesised and assessed for antitrypanosomatid activity. An antileishmanial early lead, analogue 23, acting through ROS generation and hence oxidative stress, was uncovered.
Maryna Saayman, Janine Aucamp, Helena D. Janse van Rensburg, Christina Kannigadu, Rotondwa Mphephu, Andrew J. Swarts, Keisuke Suganuma, David D. N'Da   +7 more
wiley   +1 more source

Jonathan L. Vennerstrom: I Was Standing on the Shoulders of Giants

CHIMIA, 2023
Jonathan L. Vennerstrom grew up in Ethiopia, where he was witness to the effects of leprosy and other infectious diseases of poverty on the local population.
Lukas Meier
doaj   +1 more source

Interplay Between Infectious Diseases and the Endocrine System: An Overview and Clinical Insights

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 4, July 2026.
Infectious diseases can disrupt endocrine homeostasis through direct cytopathic injury, autoimmune dysregulation, or pathogen‐derived hormone‐like effects. Viruses and bacteria are the most frequent agents, whereas fungi and parasites contribute less commonly, even remaining clinically relevant, especially in the immunocompromised population.
Francesco Capoccia, Valentina D'Onghia, Valentina Semeraro, Esposito Susanna, Maria Elisabeth Street   +4 more
wiley   +1 more source

Clinical and Diagnostic Considerations in Laryngeal Leishmaniasis: A Systematic Review

OTO Open, Volume 10, Issue 3, July-September 2026.
Abstract Objective Laryngeal leishmaniasis is a rare, insidious manifestation of Leishmania infection with potential for life‐threatening complications. Awareness is critical for efficient and timely diagnosis. This systematic review of laryngeal leishmaniasis focuses on presentation, treatment, and the role of serological studies in the work up of ...
Joseph Celidonio, Nicholas Hamilton, Alexandra Filipkowski, Raj Malhotra, Samantha Shave, Myat E. Mon, Kenneth Yan, Rachel Kaye   +7 more
wiley   +1 more source

Therapeutic Interventions for Countering Leishmaniasis and Chagas’s Disease: From Traditional Sources to Nanotechnological Systems

Pathogens, 2019
The incidence of neglected diseases in tropical countries, such as Leishmaniasis and Chagas’s disease, is attributed to a set of biological and ecological factors associated with the socioeconomic context of developing countries and with a ...
Eliana B. Souto, João Dias-Ferreira, Sara A. Craveiro, Patrícia Severino, Elena Sanchez-Lopez, Maria L. Garcia, Amélia M. Silva, Selma B. Souto, Sheefali Mahant   +8 more
doaj   +1 more source

Flavonoids in Nasal Therapeutics: Biological Activities, Delivery Challenges, and Formulation Strategies–A Systematic Review

Phytotherapy Research, Volume 40, Issue 7, Page 4676-4709, July 2026.
Overview of the therapeutic potential of flavonoids in nasal delivery systems, highlighting their benefits to the human nasal cavity, and applications in the treatment of respiratory and brain‐related diseases. ABSTRACT Flavonoids represent a significant group of secondary metabolites.
Jeniffer Viviana Ramirez Hernández, Sara Elis Bianchi, Flávia Nathiely Silveira Fachel, Elizandra Braganhol, Sheila Porto de Matos, Valquíria Linck Bassani   +5 more
wiley   +1 more source

Antiviral Activity of Approved Antibacterial, Antifungal, Antiprotozoal and Anthelmintic Drugs: Chances for Drug Repurposing for Antiviral Drug Discovery

Journal of Experimental Pharmacology, 2022
Leena Abdulaziz,1 Esraa Elhadi,1,2 Ejlal A Abdallah,3 Fadlalbaseer A Alnoor,4 Bashir A Yousef5 1Department of Pharmacology, Faculty of Pharmacy, Omdurman Islamic University, Khartoum, 14415, Sudan; 2Jiangsu Key Laboratory of Drug Screening, China ...
Abdulaziz L, Elhadi E, Abdallah EA, Alnoor FA, Yousef BA   +4 more
doaj  

Some nitroimidazole derivatives as antibacterial and antifungal agents in in vitro study

Journal of Medical Science, 2019
Nitroimidazoles have wide range of therapeutic uses mainly as anaerobic antibacterials and antiprotozoal agents. Some bicyclic nitroimidazodihydrooxazoles and nitroimidazotetrahydrooxazines are found to be antituberculosis agents.
Justyna Żwawiak, Dorota Olender, Lucjusz Zaprutko   +2 more
doaj   +1 more source

Evaluation of the Utilization Pattern of Veterinary Drugs in Selected Veterinary Clinics of Mekelle City, Tigray, Ethiopia

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
Veterinary drug utilization patterns were assessed in three veterinary clinics in Mekelle City, Ethiopia. Antimicrobials, particularly oxytetracycline, constitute the majority of prescriptions, followed by anthelmintics. Drug prescribing frequently relies on tentative diagnosis rather than evidence‐based diagnostic procedures.
Helen Hagos, Mebrahtu Weldegebriel, Hagazi Fantay, Haftom Yirga Tsegay   +3 more
wiley   +1 more source

Blood Protozoan Infection Disrupts Ovarian Follicular Development in Dairy Cattle: A Mechanistic Link to Reproductive Failure

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
Subclinical haemoprotozoan infection disrupts RBC integrity, and that leads to decreased Hb level and excess free iron in plasma. That subsequently impairs ovarian follicular development and thereby builds up a mechanistic link to reproductive failure in dairy cattle.
Most. Mousumi Akter, Md. Sadequl Islam, Md. Ashraful Islam, Md. Mahmudul Hasan, Rakibul Islam, Md. Mominul Islam, Md. Gausur Rahman, Md. Shafiqul Islam, Anup Kumar Talukder, Md. Bazlar Rashid   +9 more
wiley   +1 more source