Results 41 to 50 of about 5,274,206 (218)
Amebiasis caused by Entamoeba histolytica is nowadays a serious public health problem worldwide, especially in developing countries. Annually, up to 100,000 deaths occur across the world.
Ramiro Quintanilla-Licea +4 more
doaj +1 more source
Betulinic acid (BA, 3β-hydroxy-lup-20(29)-en-28-oic acid) is a pentacyclic triterpene acid present predominantly in Betula ssp. (Betulaceae) and is also widely spread in many species belonging to different plant families.
André Barreto Cunha +3 more
doaj +1 more source
hERG1 channels and potential therapeutics for long QT syndrome
Abstract figure legend Prolonged QT results from hERG1 channel dysfunction. (A) Physiological anterograde trafficking of hERG1 channels to the plasma membrane, leading to a normal electrocardiogram. (B) Prolonged QT results from the presence of fewer hERG1 channels on the plasma membrane due to decreased anterograde trafficking or reduced function due ...
Elizabeth H. Schneider +3 more
wiley +1 more source
A Review on Green Synthetic Approaches in the Development of Quinoline Analogues
This review highlights recent advances in environmentally friendly approaches, including metal‐free systems, solvent‐free approaches, microwave, and ultrasonic‐assisted techniques, organo‐ and biocatalysis, ionic liquids, nanoparticle catalysis, electrochemical, and photocatalytic strategies for the synthesis of quinoline scaffolds.
Demis Zelelew +3 more
wiley +1 more source
Search for new selective antiprotozoal agents [PDF]
Se da la información general sobre los fármacos antiprotozoarios que están usándose en clínica, se discuten nuevas dianas de los parásitos protozoarios útiles en la búsqueda de nuevos agentes antiprotozoarios, enfocando la atención al rol biológico de ...
Kouznetsov, Vladimir V +1 more
core
Exploring the potential of chloroquine and quinacrine derivatives as new antiprotozoal and tumour drug resistance reversal agents [PDF]
Bibliography: leaves 108-113.Compounds containing the quinoline and acridine moieties have been utilized extensively in the search for new antiprotozoal and multidrug resistance reversal agents. Hence, these moieties formed the basis for the synthesis of
Haupt, Hayley Claire
core +1 more source
Investigation of 5’-Norcarbocyclic Nucleoside Analogues as Antiprotozoal and Antibacterial Agents
Carbocyclic nucleosides have long played a role in antiviral, antiparasitic, and antibacterial therapies. Recent results from our laboratories from two structurally related scaffolds have shown promising activity against both Mycobacterium tuberculosis ...
Anastasia L. Khandazhinskaya +13 more
doaj +1 more source
Furanocoumarins from Ruta chalepensis with Amebicide Activity
Entamoeba histolytica (protozoan; family Endomoebidae) is the cause of amoebiasis, a disease related to high morbidity and mortality. Nowadays, this illness is considered a significant public health issue in developing countries.
Aldo Fabio Bazaldúa-Rodríguez +5 more
doaj +1 more source
Nanoparticles, including green magnesium nanoparticles, facilitate passage through cellular membranes in animals and interact efficiently with biological systems, improving their functional activity. The results indicated that BNMg supplementation enhances performance, antioxidant efficacy, immune system status, blood mineral concentrations, digestive ...
Fayiz M. Reda +7 more
wiley +1 more source
The synthesis and in-vitro antiprotozoal evaluation of novel N(4)-(benzyl)spermidyl-linked bis(1,3,5-thiadiazinane-2-thione) (bis-THTT) derivatives from N(4)-(benzyl)spermidine is disclosed. Several of the new bis-THTT have in-vitro activities against L.
Julieta Coro +13 more
core +1 more source

