Results 61 to 70 of about 8,093 (191)
Journal of Fish Diseases, Volume 49, Issue 4, April 2026.ABSTRACT The gill parasite Sparicotyle chrysophrii poses a significant threat to gilthead sea bream (Sparus aurata) aquaculture in the Mediterranean, causing considerable mortality and economic losses. As traditional chemotherapeutic treatments, like formalin, face growing regulatory restrictions, there is an urgent need for alternative control ...
Teresa Pirollo +8 more
wiley +1 more source
Chemistry &Biodiversity, Volume 23, Issue 3, March 2026.Ethanolic extracts from leaves, stems, and roots of Schinus weinmanniifolia Mart. ex Engl. were evaluated for phytochemical composition and biological activities. The extracts exhibited antioxidant, photoprotective, and antimicrobial activity, without hemolytic effects or cytotoxicity at active concentrations. Syringic acid, epicatechin, and rutin were
João Andrade +14 more
wiley +1 more source
Identifying Drugs Associated With Parkinson's Disease Risk Using Machine Learning
Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 3, March 2026.ABSTRACT Machine learning (ML)–based methods have been proposed as a potential approach for identifying candidate drugs to be repurposed as disease‐modifying treatments for Parkinson's disease (PD). We applied an ML‐based signal detection method to identify drugs associated with PD and evaluated the method's generalizability.
Eeva Pylkkö +8 more
wiley +1 more source
Equine protozoal myeloencephalitis—Presentation and progression
Equine Veterinary Education, Volume 38, Issue 3, Page 132-134, March 2026.Summary Equine protozoal myeloencephalitis (EPM) remains one of the most frequently diagnosed neurological disorders of horses in North America, caused primarily by Sarcocystis neurona and less commonly Neospora hughesi. The clinical presentation is highly variable due to multifocal involvement of both grey and white matter, with asymmetric ataxia and ...
S. Austin, S. Gray
wiley +1 more source
Advanced Science, Volume 13, Issue 12, 27 February 2026.Solution structures of a series of cyclic lipodepsipeptides from Pseudomonas reveal that these specialized metabolites adopt left‐handed alpha helical conformations of only two types, being either ‘stapled’ or ‘catch‐pole’ helix. The particular modular distribution of the biosynthetic gene clusters is found to determine the extent of their conserved ...
Benjámin Kovács +9 more
wiley +1 more source
Benzoxaboroles Are Inhibitors of the η‐Class Carbonic Anhydrase From Plasmodium falciparum
Archiv der Pharmazie, Volume 359, Issue 2, February 2026.Benzoxaborole‐based inhibitors demonstrate potent, low‐micromolar inhibition of the essential malaria target PfaCA and are effective in vitro suppression of P. falciparum. Molecular docking confirms target engagement via zinc coordination, establishing this chemotype as a promising scaffold for the development of next‐generation antimalarials ...
Alessandro Bonardi +9 more
wiley +1 more source
Surveillance of Drug Residue Profiles in Gallus gallus domesticus (Silkie Chickens) in Taiwan
AnimalsVeterinary drugs are extensively utilized in poultry farming for purposes such as disease prevention, disease treatment, and feed efficiency enhancement. However, the application of these drugs can lead to unacceptable residues in edible products.
Chiao-Hsu Ke, Jr-Wei Chen, Chen-Si Lin
doaj +1 more source
The Role of Natural Products in Drug Discovery and Development against Neglected Tropical Diseases
Molecules, 2016 Endemic in 149 tropical and subtropical countries, neglected tropical diseases (NTDs) affect more than 1 billion people annually, including 875 million children in developing economies. These diseases are also responsible for over 500,000 deaths per year
Peter Mubanga Cheuka +3 more
doaj +1 more source
Food Science &Nutrition, Volume 14, Issue 2, February 2026.Spiranthes spiralis L. seed methanol extract was morphologically and chemically characterized using microscopy, FT‐IR, GC–MS, and in silico analyses. The extract exhibited high phenolic content and strong DPPH radical scavenging activity, while GC–MS identified 22 bioactive compounds with notable binding affinity toward the GPR52 receptor.
Erdi Can Aytar +7 more
wiley +1 more source
Ecological Entomology, Volume 51, Issue 1, Page 86-97, February 2026.We investigated how temperature and relative humidity influence the parasitic fungus Hesperomyces harmoniae on the invasive ladybird Harmonia axyridis under controlled laboratory conditions. Abiotic factors significantly affect parasitism: High relative humidity increased parasite prevalence, development rate, and load, while both low and high ...
Michiel D. de Groot +8 more
wiley +1 more source