Quantitative Structure ‒ Antiprotozoal Activity Relationships of Sesquiterpene Lactones [PDF]
Molecules, 2009 Prompted by results of our previous studies where we found high activity of some sesquiterpene lactones (STLs) against Trypanosoma brucei rhodesiense (which causes East African sleeping sickness), we have now conducted a structure-(in-vitro)-activity ...
Reto Brun +4 more
doaj +5 more sources
Antiprotozoal Activity of (E)-Cinnamic N-Acylhydrazone Derivatives [PDF]
Molecules, 2014 A series of 14 (E)-cinnamic N-acylhydrazone derivatives, designed through molecular hybridization between the (E)-1-(benzo[d][1,3]dioxol-5-yl)-3-(4-bromophenyl)prop-2-en-1-one and (E)-3-hydroxy-N'-((2-hydroxynaphthalen-1-yl)methylene)-7-methoxy-2 ...
Samir Aquino Carvalho +4 more
doaj +6 more sources
The Potassium Channel Blocker β-Bungarotoxin from the Krait Bungarus multicinctus Venom Manifests Antiprotozoal Activity [PDF]
Biomedicines, 2023 Protozoal infections are a world-wide problem. The toxicity and somewhat low effectiveness of the existing drugs require the search for new ways of protozoa suppression.
Alexey V. Osipov +9 more
doaj +2 more sources
Synthesis, Antiprotozoal Activity, and Cheminformatic Analysis of 2-Phenyl-2H-Indazole Derivatives [PDF]
Molecules, 2021 Indazole is an important scaffold in medicinal chemistry. At present, the progress on synthetic methodologies has allowed the preparation of several new indazole derivatives with interesting pharmacological properties.
Karen Rodríguez-Villar +9 more
doaj +2 more sources
Antiprotozoal Activity of Xanthone Derivatives
Orbital: The Electronic Journal of Chemistry, 2020 A series of xanthone derivatives containing different side chains, including ω-bromo and ω-aminoalkoxylxanthones (with linear alkoxy chains of 3, 4 and 5 carbon atoms and methyl, propyl, tert-butylamino and piperidinyl moieties), synthesized from the ...
Ana Camila Micheletti +5 more
doaj +4 more sources
Antiprotozoal activity of Boesenbergia rotunda (L.) Mansf and Ganoderma lucidum (Fr.) Kart extracts against Blastocystis hominis [PDF]
Veterinary World, 2023 Background and Aim: Blastocystis hominis is an intestinal protozoan in humans and animals. The parasite causes mild-to-severe intestinal complications, such as diarrhea, in healthy humans and immunocompromised hosts.
Chalermpon Kaewjai +3 more
doaj +2 more sources
Antiprotozoal activity of different Xenorhabdus and Photorhabdus bacterial secondary metabolites and identification of bioactive compounds using the easyPACId approach [PDF]
Scientific Reports, 2022 Natural products have been proven to be important starting points for the development of new drugs. Bacteria in the genera Photorhabdus and Xenorhabdus produce antimicrobial compounds as secondary metabolites to compete with other organisms. Our study is
Sebnem Hazal Gulsen +13 more
doaj +2 more sources
Synthesis and Antiprotozoal Activity of Azabicyclo-Nonane Pyrimidine Hybrids [PDF]
Molecules, 2022 2,4-Diaminopyrimidines and (dialkylamino)azabicyclo-nonanes possess activity against protozoan parasites. A series of fused hybrids were synthesized and tested in vitro against pathogens of malaria tropica and sleeping sickness.
Clemens Hinteregger +6 more
doaj +2 more sources
Antiprotozoal Activities of Millettia richardiana (Fabaceae) from Madagascar [PDF]
Molecules, 2014 With at least 60% of the Millettia species (Fabaceae) being in medicinal use, we found it relevant to assess the potential antiprotozoal and antifungal activities of Millettia richardiana.
Manitriniaina Rajemiarimiraho +9 more
doaj +3 more sources
Antiprotozoal and antimycobacterial activities of Persea americana seeds [PDF]
BMC Complementary and Alternative Medicine, 2013 Persea americana seeds are widely used in traditional Mexican medicine to treat rheumatism, asthma, infectious processes as well as diarrhea and dysentery caused by intestinal parasites.The chloroformic and ethanolic extracts of P. americana seeds were prepared by maceration and their amoebicidal, giardicidal and trichomonicidal activity was evaluated.
Jiménez-Arellanes, Adelina +5 more
openaire +4 more sources